my 1st week phase 1 trail

cyndi2324
cyndi2324 Member Posts: 72
edited March 2014 in Colorectal Cancer #1
Hello!
I just wanted to post how my 1st week phase 1 trial of ARRY-438162 went. my history is I was originally diagnosed 2007 with colon cancer that had ruptured and gone into my abdomen. The 1st year I had surgery and 4fu and xeloda chemo. Two months after my chemo I felt something was wrong again. My wonderful Dr. had me do a pet scan and it was positive in 4 new places still in my colon and abdomen. She said I need a gene test for kras and surgery . I had more surgery a colostomy and chemo CPT11, Camptosar. I do have the mutated kras gene so the 1st and 2nd treatments didn't work. I am now getting as my chemo in pill form called ARRY-438162 at START (South Texas Accelerated Research Therapeutics. I had mett with my new Dr. and staff last week. Fri. they had me do a base line CT, ECG and labs. Mon. very early I got more labs and ECG then I got the drug. I had more labs, ECG, and vital signs for the next 12 hrs. Wow that was a long day. I came back Tue am for vital signs labs, ECG and then was given the drug waited an hour or 2 had vitals again then was given 1 weeks supply of pills. I take 3 pills 2 times a day 12 hr apart. I go back tomorrow Mon. to do more of the same but not a 12 hour day.I also see Dr. Patnaik on mon. The side affects of what I'm taking for me have been 2 days with diarrhea a little fatigue, and a lite rash on the lower part of my face.
After 3 weeks of this I get another CT for Dr. Patnaik to compare to my base line CT. If my cancer is the same size or smaller I continue with this trial. I won't know the about CT results till right after Chrismas. So I'm praying that they are shrinking or at the very least not growing. Everyone here has been kind, helpful and caring.
Cyndi

Comments

  • Sonia32
    Sonia32 Member Posts: 1,071 Member
    cyndi
    l hope this trial works for you and l pray that your ct scan shows signs of improvement hugs sonia
  • AnneCan
    AnneCan Member Posts: 3,673 Member
    Thanks for updating all of
    Thanks for updating all of us & good luck with your new regimen!
  • Kathryn_in_MN
    Kathryn_in_MN Member Posts: 1,252 Member
    Hi Cyndi
    Wow - what a long day for you. But it is exciting you have something new to try. I hope this shrinks all your tumors and the side effects stay minimal. Please keep us updated.

    I really appreciate all of you that do trials. You are brave and might help a lot of us in the future.
  • Fight for my love
    Fight for my love Member Posts: 1,522 Member
    Hi Cyndi,you are in my
    Hi Cyndi,you are in my prayers.I hope the trial goes well and the medication is working and killing all the cancer cells.Good luck with it.Take care.
  • Annabelle41415
    Annabelle41415 Member Posts: 6,742 Member
    Treatments
    So glad that your doctor is keeping you informed and changing treatments if necessary. I hope that things go well with your CT scan and your treatments. Keep us informed.

    Kim
  • tootsie1
    tootsie1 Member Posts: 5,044 Member
    Thanks for letting us know
    Cyndi, good luck with it. We're behind you!

    *hugs*
    Gail
  • KATE58
    KATE58 Member Posts: 299
    tootsie1 said:

    Thanks for letting us know
    Cyndi, good luck with it. We're behind you!

    *hugs*
    Gail

    GOOD LUCK CYNDI!
    I'LL KEEP

    GOOD LUCK CYNDI!

    I'LL KEEP YOU IN MY PRAYERS
    GOD BLESS
    KATE
  • jillpls
    jillpls Member Posts: 238
    bless you
    Yes, bless you for paving the way with trying a new drug. It takes strength and courage to go forward and discover the unknown. I will be thinking of you and praying that it's the next new miracle drug to stop all colorectal cancer
  • sfmarie
    sfmarie Member Posts: 602
    Hugs
    Thank you for sharing. Happy Thanksgiving. My prayers this trial works for you. Marie
  • damama24
    damama24 Member Posts: 174 Member
    KATE58 said:

    GOOD LUCK CYNDI!
    I'LL KEEP

    GOOD LUCK CYNDI!

    I'LL KEEP YOU IN MY PRAYERS
    GOD BLESS
    KATE

    Good luck Cyndi I am
    Good luck Cyndi I am participating in a phase one drug trial also and those first few sessions made for very long days. I pray that this new drug works for you as I hope the drug I am receiving works for me Keep good and positive thoughts Deb