my 1st week phase 1 trail

cyndi2324

Hello!
I just wanted to post how my 1st week phase 1 trial of ARRY-438162 went. my history is I was originally diagnosed 2007 with colon cancer that had ruptured and gone into my abdomen. The 1st year I had surgery and 4fu and xeloda chemo. Two months after my chemo I felt something was wrong again. My wonderful Dr. had me do a pet scan and it was positive in 4 new places still in my colon and abdomen. She said I need a gene test for kras and surgery . I had more surgery a colostomy and chemo CPT11, Camptosar. I do have the mutated kras gene so the 1st and 2nd treatments didn't work. I am now getting as my chemo in pill form called ARRY-438162 at START (South Texas Accelerated Research Therapeutics. I had mett with my new Dr. and staff last week. Fri. they had me do a base line CT, ECG and labs. Mon. very early I got more labs and ECG then I got the drug. I had more labs, ECG, and vital signs for the next 12 hrs. Wow that was a long day. I came back Tue am for vital signs labs, ECG and then was given the drug waited an hour or 2 had vitals again then was given 1 weeks supply of pills. I take 3 pills 2 times a day 12 hr apart. I go back tomorrow Mon. to do more of the same but not a 12 hour day.I also see Dr. Patnaik on mon. The side affects of what I'm taking for me have been 2 days with diarrhea a little fatigue, and a lite rash on the lower part of my face.
After 3 weeks of this I get another CT for Dr. Patnaik to compare to my base line CT. If my cancer is the same size or smaller I continue with this trial. I won't know the about CT results till right after Chrismas. So I'm praying that they are shrinking or at the very least not growing. Everyone here has been kind, helpful and caring.
Cyndi

Sonia32

cyndi
l hope this trial works for you and l pray that your ct scan shows signs of improvement hugs sonia

AnneCan

Thanks for updating all of
Thanks for updating all of us & good luck with your new regimen!

Kathryn_in_MN

Hi Cyndi
Wow - what a long day for you. But it is exciting you have something new to try. I hope this shrinks all your tumors and the side effects stay minimal. Please keep us updated.

I really appreciate all of you that do trials. You are brave and might help a lot of us in the future.

Fight for my love

Hi Cyndi,you are in my
Hi Cyndi,you are in my prayers.I hope the trial goes well and the medication is working and killing all the cancer cells.Good luck with it.Take care.

Annabelle41415

Treatments
So glad that your doctor is keeping you informed and changing treatments if necessary. I hope that things go well with your CT scan and your treatments. Keep us informed.

Kim

tootsie1

Thanks for letting us know
Cyndi, good luck with it. We're behind you!

*hugs*
Gail

KATE58

tootsie1 said:

Thanks for letting us know
Cyndi, good luck with it. We're behind you!

*hugs*
Gail

GOOD LUCK CYNDI!
I'LL KEEP
GOOD LUCK CYNDI!

I'LL KEEP YOU IN MY PRAYERS
GOD BLESS
KATE

jillpls

bless you
Yes, bless you for paving the way with trying a new drug. It takes strength and courage to go forward and discover the unknown. I will be thinking of you and praying that it's the next new miracle drug to stop all colorectal cancer

sfmarie

Hugs
Thank you for sharing. Happy Thanksgiving. My prayers this trial works for you. Marie

damama24

KATE58 said:

GOOD LUCK CYNDI!
I'LL KEEP
GOOD LUCK CYNDI!

I'LL KEEP YOU IN MY PRAYERS
GOD BLESS
KATE

Good luck Cyndi I am
Good luck Cyndi I am participating in a phase one drug trial also and those first few sessions made for very long days. I pray that this new drug works for you as I hope the drug I am receiving works for me Keep good and positive thoughts Deb