Devastating update

That's great advice, I do feel confident on taking him. Now when I thought about it seems that the worst would be not to take him.

Sorry for your loss, I hope time is healing somewhat of it. I can feel your pain about not seeing loved ones, COVID indeed is the worst devil, I've lost my beloved grandmother last year and they didn't let anyone near her for 7 days, while she lost her memory, was confused, and scared in the hospital.

Thanks, Abita.

I really hope that is the case, I am actively looking for trials, Looking at him no one can even think that he is fighting such a deadly disease, hoping something would work out for him.

Yes, we didn't communicate before, I wasn't much involved with the forum, had too many things going on but I made some adjusted so less occupied now.

Thanks, I am going to discuss with the Oncologist to see if we can continue the drug a little longer because his CEA didn't increase much in the last 3 weeks and bone lesions were likely were there since PET scans in July.

It's sad that one doesn't qualify for too few spots but just be cautious that if at all it moves outside of the liver they may not consider it, at least that was the case with my dad, two months I prepared myself both physically and mentally to donate a part of the liver and hit the wall as soon as the PET scan results came in.

If you are around the tri-state area check this out, I met with the surgeon a couple of times, even if you are not close to him, he and the team responded well via email and call https://clinicaltrials.gov/ct2/show/NCT04742621

Feel free to message me if you need any additional information.

Hey, Thanks again for all the information.

I checked trials in India from Imugene he is not eligible for the trial mostly due to his previous HER2 therapy, as well contact them via Email for the Vaxinia trial which is approved in USA but hasn't started.

Meanwhile, visited MSKCC and after one week their research team said he is not eligible for any trial at the moment, asked if any particular reason they didn't find him a trial, like low Hemoglobin, high kidney number, waiting on their response.

Simuletnoulsy, I did research on my own and reached out to an investigator who led the trial for the medicine that we tried (and failed), and from that came a suggestion for a trial drug (Enhertu) that he might be worth a try for him https://clinicaltrials.gov/ct2/show/NCT04744831. His oncologist was on it and got it approved from Insurance two days back

Since his bone Mets started causing pain, the plan is to do the radiation as well to start with the trial drug. So we are hopeful. Once he goes through a couple of 3-week cycle, will head to India :)

Hello All,

The radiation got rescheduled and overlapped with Chemo, met with multiple doctors, done blood transfusion but in the end we made it to India for little over 3 weeks and got back. He did amazingly well while we were there.

As of now, taking one day at a time and Continuing his treatment with the Enhertu, which is keeping his CEA stable

Can't thank enough everyone for courage and optimism.

It's a trial drug for colon cancer but it's been studied/used in Breast cancer for a long time.

The drug is specific for a genomic marker that is Her2 amplification (Her2 +) . The marker is rare in colon cancer but does occur in 2-3% of CRC. Only a couple of people have that in CRC forum.