Post RP and SRT journey - oh joy
Been wondering - is 0.07 for
Been wondering - is 0.07 for a first post SRT result with TRT back to normal a typical number?
edited March 2019 #103Pretty good
It is pretty good as the limit of detection for the two PSA assays that I have used were <0.05 ( Architect Abbott chemiluminescence CMIA ( serum ) and <0.03 Cobas Roche electrochemiluminescence ECLIA sandwich (serum plasma) so you are close to the limit of detection.
Sometimes it does bounce around a bit or take a long time to decline as the last cancer cells drop dead.
You just have to wait and see what it does next! Hopefully it will stay stable, fall below the limit of detection and stay there.
Yea that is what I hoped.
Yea that is what I hoped.
Kind of makes up for the fact that I finally ran the MSK nomograms for what I think are my numbers.
I got 75% chance of no progression at 6 years on the post SRT one which is good and 5 / 18 / 34% chance of looking skyward on the 5 / 10 / 15 life expectancy one with a very dodgy guess on DT which is less good.
I have been feeling in a vacuum of late and felt it better to know the possible futures as my onco never discussed these with me.
One has to hope that these figures are old and there is another ten years of advancement to look forward to.
I am prepared to give you a 100 % chance of not dying from prostate cancer in five years, even if it went wild tomorrow it would be controllable with ADT for several years, it will take several years to metastase to your vital organs, etc at the quickest. No way, barring a wayward bus, etc, you will be here in five years.
Ten years, pretty much 95%, even if it goes mad in a few years time, we can still hold it back for a long while.
Fifteen years, the crystal ball is a bit misty, check back on that one in 2023 or there abouts, something else might get you first! :-)
I appreciate the comments. I
I appreciate the comments. I'm overthinking at the moment and feeling sad for my family. I've seen what end of life stuff can do and I dread putting them through that. I suspect I'll make sure that does not become an issue at the right time.
Onwards and upwards!0
No definite thresholds after ADT
PSA=0.07 is quite low. Thresholds for remission after surgery or SRT are at the range of <0.05 ng/ml, but there is no typical values representing something after ADT. Our system never returns to the previous status because of the estrogens that now play a role in our hormonal system. Estrogens substituted the Testosterone in certain functions while we were on castration. Now, even with T back to higher levels there will be always a role plaied by the estrogens. You may check its levels too.
In fact, Estrogens patches are typically used to improve patients status when on ADT.
We never know what is reserved for us in the future. Now is time for celebration instead of worring.
I am going through an introspective phase at the moment as the suprise at a good number has worn off and I am processing worst case scenarios as is my rather annoying way.
I definitely need to live in the moment!
You just have to try and get over it.
Your numbers are good, you have a very good chance of putting prostate cancer behind you.
Spring is here in northern France and I saw a young lady with a shapely bottom in painted on jeans today and I was in instant randy mode despite twelve months of degarelix.
Off to tickle up the old girl!
You are right - it is
You are right - it is starting to affect my wife so I need to nut up and shut up.
I see you are suffering the effect of "Springtime in Paris" down your necck of the woods0
Just realised it has been
Just realised it has been four months since my last test and I have not heard from the hospital. Time to ring them up and nag them.
When I realised it was due, my anxiety levels rose from "too busy to think about it" to "oh **** here we go again"
Found the letter. Had buried it in a pile of paperwork. Freud would probably explain why.
Test due this coming week.0
Jumpin' Jeroboams Batman,
I have mine next week as well, I can go in when I like so I have picked Tuesday morning with the results Tuesday evening.
I am doing PSA, blood glucose, cholesterol, etc all at the same time, I have to schedule a conference with Dr Pooh later in the week to stock up on pills! :-)
Best of luck,
I know a few people due in the next week or so. Lets hope we all pass muster.
I am channeling Pooh and Piglet right now rather then Eyore
I went and gave some blood to the local vampires this morning, one of the senior biochemists did mine so no bruising, etc, I have had some bad jobs before.
Results at 17:00 ce soir.
Dr Pooh is on her hollies so I went and got an advance of a month on the pills at the local pharmacy.
Rum at the ready!
I am with Tigger in spirit,
Says it all really, champagne tonight!0
You are still on HT yes?0
Let us know your results. I hope they fit your expectations.
It is awesome to have a PSA at less than 0.05 ng/ml. Let's hope for continuous similar levels after the Firmagon. I think that your chemical castration is now at its 18 months mile stone. This is a long period so I recommend you to check the functionality of those organs that involve the production of hormones for our systems to work well. The typhoid and the Adrenal glands have been replacing the testis to certain extent. The liver, pancreas and the kidneys in particular could have been affected. Checking the creatinine at 24 hours and an ionogram is good to understand how far Firmagon has affected you, apart from the great benefit in controlling PCa.
ADT in my case assume some responsibility in the CKD case development. I detected its effects from the periodical test results (lipids, image studies and symptoms) I am doing since 2000. Diet influences much any situation.
Best to you both.
But I am thinking of jumping at the end of September, which will be my 19th injection including the induction double, if I score another below the limit of dectection.
Tigger is against this but I want my life back.
If I do this then by the end of January I will be running on fumes as far as degarelix is concerned.
It is hard to say what will happen after that.
Anyway I am still below the limit of detectability when Eeyore had me down for the dreaded castrate resistant cancer to be going rampant by now.
Now for the Côtes du Rhone and a cuddle!
Best of luck with your own private battle,
Last result - 0.07
Last result - 0.07
This one - 0.050
edited July 2019 #120Masked results need to be avoided
Is it the first PSA (0.07) post ADT?
I wonder the level of the Testosterone. You should get a value to certify if the result is not masked by the HT influence.
Last HT jab (triptorelin) was early August 2018
RT was last week of August to last week of October 2018
First review post RT was end of Feb 2019 - PSA - 0.07, Test 14
This PSA early July was 0.05
Next ttest in four months
Bear in mind my PSA prior to HT was way down around 7 due to crap lifestyle so the first post RT review was at twice my legacy Test level and the PSA has dropped twice with higher Test levels.
My feelings are rather complex at the moment but generally complex.
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