This year I was diagnosed with lumbar sacral radiation plexopathy with myokymia - 23 years after having had colon cancer (I was only 31 when diagnosed with cancer). Thank God I had my children prior to this happening and that treatment (radiation) was available as it more than likely saved my life. Looking back, I can say I've always had some of the symptoms but they were tolerable - now however, it's a constant disruption to my life. I have constant tighting, twitching, aching, buzzing from my buttocks down to the tips of my toes along with some jerking in my feet. I don't have "pain" so to say, however the constant systoms is enough to drive you crazy. I've seen a Neurologist who has prescribed gabapentin - so far, no change but am being told to give it a chance. I also take vicoden to help calm the buzzing/aching in my legs. I also try to keep active by walking every day and doing some strengthening and stretching exercises because I'm afraid if I don't then I'll loose the use. Does anyone out there have any other ideas for dealing with this ??