NEW CHEMO

arbor3
arbor3 Member Posts: 103
edited March 2014 in Ovarian Cancer #1
I finished my 3rd round of chemo on April 6th, had a CT scan on April 13th. The scan showed that I have a Liver Dome Lesion that is enlarging. My ONC wants to put me back on Chemo starting June 1st. My old Chemo was Abraxane, the new is Doxil. I am stage 4 ovarian cancer. I was wongering is anyone had been on Doxil. The side effects make me nervous and scared. I have already had the Heart Scan and it was good.

Dinora

Comments

  • saundra
    saundra Member Posts: 1,370 Member
    #2
    Search
    You can do a search by typing in "Doxil" on the topic page and read past posts on the chemo. I have not had this yet. Only taxol/carbo.....Saundra
  • BonnieR
    BonnieR Member Posts: 1,526 Member
    #3
    Doxil
    Dear Dinora, sorry to hear you have to go on another chemo but wanted you to know the side affects can be managed if you follow all the dos and don't. If you don't find what you need I'll post them for you. :-) Hugs N Prayers Bonnie
  • arbor3
    arbor3 Member Posts: 103
    #4
    BonnieR said:

    Doxil
    Dear Dinora, sorry to hear you have to go on another chemo but wanted you to know the side affects can be managed if you follow all the dos and don't. If you don't find what you need I'll post them for you. :-) Hugs N Prayers Bonnie

    NEW CHEMO
    THANK YOU FOR RESPONDING SAUNDRA AND BONNIE. I DID LOOK UP EVERYTHING ON DOXIL AND THE SIDE EFFECTS. I START JUNE 1ST AND WILL LET YOU KNOW HOW I DO. I HAVE BEEN ON TAXOL, CARBO AND ABRAXANE AND DID AS WELL AS I EXPECTED. SO LOOKING AT THE PRINTOUTS IT HELPED.
    THANK YOU AGAIN
    HUGS!!!!!!!!DINORA
  • galaxygirl
    galaxygirl Member Posts: 4
    #5
    arbor3 said:

    NEW CHEMO
    THANK YOU FOR RESPONDING SAUNDRA AND BONNIE. I DID LOOK UP EVERYTHING ON DOXIL AND THE SIDE EFFECTS. I START JUNE 1ST AND WILL LET YOU KNOW HOW I DO. I HAVE BEEN ON TAXOL, CARBO AND ABRAXANE AND DID AS WELL AS I EXPECTED. SO LOOKING AT THE PRINTOUTS IT HELPED.
    THANK YOU AGAIN
    HUGS!!!!!!!!DINORA

    Doxil
    Sorry to say that Doxil is not working for me. This is my second round of repeating chemo. Took Taxol,Carbo last year. Diagnosed with Peritoneal/Ovarian. Was in remission for only three months. Put on Doxil, taking it now for four months, once a month and CTscan shows no improvement. Fluid is building up again. Side effects from Doxil is known as after effect which I am getting now.
  • bgsvatek
    bgsvatek Member Posts: 4
    #6
    arbor3 said:

    NEW CHEMO
    THANK YOU FOR RESPONDING SAUNDRA AND BONNIE. I DID LOOK UP EVERYTHING ON DOXIL AND THE SIDE EFFECTS. I START JUNE 1ST AND WILL LET YOU KNOW HOW I DO. I HAVE BEEN ON TAXOL, CARBO AND ABRAXANE AND DID AS WELL AS I EXPECTED. SO LOOKING AT THE PRINTOUTS IT HELPED.
    THANK YOU AGAIN
    HUGS!!!!!!!!DINORA

    Hi Dinora
    Hi Dinora
    I just wanted to let you know that I had my first treatment of Doxil 2 weeks ago and did not have any side effects. I did follow the rules to a T as Bonnie suggested. I have to admit I was pretty worried also about the side effects but I had nothing, thank God.. I"ll keep you posted... My next treatment is June 9
    God bless!
    Blanca
  • BonnieR
    BonnieR Member Posts: 1,526 Member
    #7
    bgsvatek said:

    Hi Dinora
    Hi Dinora
    I just wanted to let you know that I had my first treatment of Doxil 2 weeks ago and did not have any side effects. I did follow the rules to a T as Bonnie suggested. I have to admit I was pretty worried also about the side effects but I had nothing, thank God.. I"ll keep you posted... My next treatment is June 9
    God bless!
    Blanca

    Just a quick reminder they are cumulative, so stay deligent. Glad it is going well for you. Hugs N Prayers Bonnie
  • Linn1
    Linn1 Member Posts: 47
    #8
    Hi Dinora
    Just wondering how you are doing with the new chemo drug? I am also stage 4 with a recurrence. Docs wanted me to participate in a clinical study at Natl. Cancer Inst. but it closed. Now the recommendation is for Gemzar and Taxotere. I have heard of Doxil but never been on the drug. Are you managing, at home or at the hospital? I hope to meet with my oncologist Wed., if I can I'll bring up Doxil and see what I can find out.

    Good luck. I'm sending positive thoughts to you and all as we cont. to fight. Hang in there.
    Lynn
  • arbor3
    arbor3 Member Posts: 103
    #9
    Linn1 said:

    Hi Dinora
    Just wondering how you are doing with the new chemo drug? I am also stage 4 with a recurrence. Docs wanted me to participate in a clinical study at Natl. Cancer Inst. but it closed. Now the recommendation is for Gemzar and Taxotere. I have heard of Doxil but never been on the drug. Are you managing, at home or at the hospital? I hope to meet with my oncologist Wed., if I can I'll bring up Doxil and see what I can find out.

    Good luck. I'm sending positive thoughts to you and all as we cont. to fight. Hang in there.
    Lynn

    NEW CHEMO
    Hi Linn

    Had my first session of Doxil two weeks ago. Was very tired and weak first week. I did not have any nausea. Last week was still tired but feeling better. The Chemo nurse told me that it would take 2 sessions to start having the hand and feet syndrome. I go for another session June 22, so will see then.

    HUGS!!!! Dinora
  • arbor3
    arbor3 Member Posts: 103
    #10
    NEW CHEMO
    Hi

    Finished my second session of Doxil on June 22. So far no bad side effects, I haven't been as tired. I have been having hot flashes,Onc Dr said that was good because the estrogen was leaving my body. She said the cancer cells thrive on the estrogen, learn something new everyday. Go for 3rd session on July 13th then I will have a CT scan to see where everything is at.

    HUGS!!!!!!! Dinora
  • BonnieR
    BonnieR Member Posts: 1,526 Member
    #11
    arbor3 said:

    NEW CHEMO
    Hi

    Finished my second session of Doxil on June 22. So far no bad side effects, I haven't been as tired. I have been having hot flashes,Onc Dr said that was good because the estrogen was leaving my body. She said the cancer cells thrive on the estrogen, learn something new everyday. Go for 3rd session on July 13th then I will have a CT scan to see where everything is at.

    HUGS!!!!!!! Dinora

    Hugs
    Hi Dinora, glad it is going well for you ~ again I say stay on top of the side affects as most people don't get them until the 3rd or 4th dose. Said a prayer for a clear ctscan for you on the 13th. Hugs Bonnie

    PS Yes estrogen is not good for the ovarian cancer and remember soy has natural estrogen.
  • saundra
    saundra Member Posts: 1,370 Member
    #12
    arbor3 said:

    NEW CHEMO
    Hi

    Finished my second session of Doxil on June 22. So far no bad side effects, I haven't been as tired. I have been having hot flashes,Onc Dr said that was good because the estrogen was leaving my body. She said the cancer cells thrive on the estrogen, learn something new everyday. Go for 3rd session on July 13th then I will have a CT scan to see where everything is at.

    HUGS!!!!!!! Dinora

    Anti estrogen
    That's why I am on the anti estrogen pill for the last 10 months. It has given me a vacation from chemo.
    Other glands produce a little estrogen, beside the ovaries.
    Glad you are doing good on Doxil. That may be what I start next. Saundra
  • ladyjogger31
    ladyjogger31 Member Posts: 289
    #13
    saundra said:

    Anti estrogen
    That's why I am on the anti estrogen pill for the last 10 months. It has given me a vacation from chemo.
    Other glands produce a little estrogen, beside the ovaries.
    Glad you are doing good on Doxil. That may be what I start next. Saundra

    Doxil
    You have gotten some really good advise from the women here. Make sure and follow thru with watching out for side affects. I had severe sunburn effect under my arms.It didn't get bad until my 4th treatment. Don't wear anything tight to cause friction.Good Luck!!
    Hugs and Prayers Terry
  • arbor3
    arbor3 Member Posts: 103
    #14
    arbor3 said:

    NEW CHEMO
    Hi

    Finished my second session of Doxil on June 22. So far no bad side effects, I haven't been as tired. I have been having hot flashes,Onc Dr said that was good because the estrogen was leaving my body. She said the cancer cells thrive on the estrogen, learn something new everyday. Go for 3rd session on July 13th then I will have a CT scan to see where everything is at.

    HUGS!!!!!!! Dinora

    NEW CHEMO
    Hi

    Thank you for the feed-back. I did not know about the estrogen levels. You ladies are so great, I need all the help i can get. I will ask my onc about the anti-estrogen pill. I have been very carefull about going out in the sun and heat, I live in Northern California and we are in a heat wave. This site has helped me so much.
    HUGS To All Dinora
  • ShirleyWig
    ShirleyWig Member Posts: 4
    #15
    My wife had 6 treatments of
    My wife had 6 treatments of Doxil. Used ice on hands and feet while getting treated. After the last treatment her feet were dark blue then turning red, with large blisters. Looked like her feet had been in a fire. Her CA125 had stopped coming down, so the treatments with Doxil were stopped. These drugs affect everyone different, but the total effect of Doxil was hard on her, and the sad part is it did not work for her. She is on Gemzar now, and it has been hard on her also. We don't know what effect it is having on the cancer yet.
  • jane65
    jane65 Member Posts: 277
    #16
    ShirleyWig said:

    My wife had 6 treatments of
    My wife had 6 treatments of Doxil. Used ice on hands and feet while getting treated. After the last treatment her feet were dark blue then turning red, with large blisters. Looked like her feet had been in a fire. Her CA125 had stopped coming down, so the treatments with Doxil were stopped. These drugs affect everyone different, but the total effect of Doxil was hard on her, and the sad part is it did not work for her. She is on Gemzar now, and it has been hard on her also. We don't know what effect it is having on the cancer yet.

    Topotecan
    Hi,
    Has your wife been on Topotecan, it only works for 30% of OVCA patients, but it worked great for me for 10 months before my CA125 began inching up.

    It's an easy chemo drug to tolerate, if she hasn't been on it yet, check with her oncologist.

    It scrambles the DNA in the cancer cells and prevents them from reproducing and they die.

    Good luck.
    Jane
  • ShirleyWig
    ShirleyWig Member Posts: 4
    #17
    jane65 said:

    Topotecan
    Hi,
    Has your wife been on Topotecan, it only works for 30% of OVCA patients, but it worked great for me for 10 months before my CA125 began inching up.

    It's an easy chemo drug to tolerate, if she hasn't been on it yet, check with her oncologist.

    It scrambles the DNA in the cancer cells and prevents them from reproducing and they die.

    Good luck.
    Jane

    Topotecan
    Will keep Topotecan in mind. She is in her 8th year. Has had 42 treatments with Carbo, taxol or both. She then took 6 Doxil, and is on her 2nd Gemzar treatment. Carbo and taxol worked good, but she is resistent to them now. Now she is on second line drugs, and we are praying one of them will work. Thanks

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