ADT Side Effects & Different ADT Drugs

Oldernow

https://csn.cancer.org/discussion/comment/1718091#Comment_1718091

I was told that as long as my PSA stays non-detectable that testosterone replacement would have no effect. It sounds counterintuitive but that's what the docs have told me.

Old Salt

Testosterone Replacement Therapy (TRT) has to be used very carefully, if at all. A full discussion is outside the focus of this thread.

Josephg

My Oncologist told me that I would have to be in remission for 5 full years, before a discussion of Testosterone replacement therapy could take place, as the risk of awakening any injured, but not yet dead cancer cells, associated with this therapy is too high. I've been under the stewardship of this Medical Oncologist specializing in PCa for almost 13 years, and I trust my life to their opinion.

alampy

All' the best.I think I wll also follow your path

eonore

https://csn.cancer.org/discussion/comment/1718127#Comment_1718127

My oncologist takes the same position. I reached the five year point last June, and still have found it hard to pull the trigger.

mamakath

Is there a correlation between length of cancer cell suppression with ADT and length of libido suppression?

Old Salt

https://csn.cancer.org/discussion/comment/1718557#Comment_1718557

Yes, basically the longer one is on ADT, the greater the CHANCE of not getting back to normal (libido etc). Age plays a major role in this as well.

Josephg

Absolutely true in some cases, but every case is different. For me, I had 2 years of ADT (Lupron, Zytiga, Prednisone) on my second round of ADT (first round was 11 years ago with Lupron, Casodex for 6 months), and today, almost 2 years after the second round of ADT treatments stopped, my Testosterone level has only risen to 27, and it is unlikely to rise much further. Hence, a permanent loss of libido. For reference, I am almost 72 in age.