Eyes on the Sparrow (trials)
Super old, American pop-culture obsessed people will immediately remember the title of this thread as the title to the theme of the old cop show "Baretta." Others will just scratch their head. The reasons I was thinking about it has little to do with cancer, but then again, the lyrics go:
Keep your eye on the sparrow,
When the going gets narrow.
We are all keeping our eye on getting better, or getting over this, which is what I will generously assume what he's saying.
You all know I like to stay up on the latest research. There is a trial that is turning heads I read about some days ago. It created a complete regresssion in 17 out of 20 tumors in mice.
Read it again if you must, complete regression.
This is not just the old, new additive to chemo, increases PFS by a week "breakthrough." It is an mRNA based treatment from BioNTech and it is starting human trials.
BioNTech promising mRNA data is the link.
There is another promising trial involving an immunological based treatment. Their animal testing results showed 7 out of 8 patients saw cleared tumors, but is less specific about the results.
Claims it clears tumors, but in the article, it only says it significantly improves survival. What does that mean?
CTX-471 could clear solid tumors.
Both of these are in phase 1 trials. Search the drug name to find them.
There are some that offer promise but if you scratch below the surface you find that maybe they are not all that promising.
Look at RO7198457, touted as promising until the company that put hundreds of millions behind it said the response rate was low.
But if you look at the articles released around the time of the phase 1 trial, it was supposed to be great. The lead researcher still thinks the idea is good despite the dismal response rate.
There are some things that give us hope, but we have to take a good look. Get in trials that are seriously promising and not just smoke and mirrors.
Eye on the sparrow...lol
Some weird formatting things happened when I posted the link I guess.
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