another possible use for mcp modified citrus pectin
this is just a good summary link. plenty of others out on the net if you suspect you have been exposed to heavy metals. do a hair test if your worried. i did, and well i think i found a likely cause of why i got my cancer.
http://www.alsearsmd.com/natural-chelation/
hugs,
Pete
Comments
-
from lef, i just bought 4 normal mcp and 2 chelation mcpsmokeyjoe said:Just curious Pete, how much
Just curious Pete, how much does MCP cost you, I bought some but it was very expensive, hard to find first of all then like a weeks supply was so costly!
with discounts and free shipping about 48 us dollars per 454g, which is a months supply the way i hammer the stuff, see the link in the other post i did about all the mcp research . it actually blocks the colon cancer receptor.
god i hope this stuff works. so its less the $2 a day or about 50cents per serve
is $12 a week expensive ? i think its reasonable. my doctor almost creamed his pants when he heard i had been on pecta a sol for 14 months. my doctor is going on a conference with the developer and owner of the company. mcp has also won some award for heavy metal chelation.
i am going to get advice directly from the scientist who developed it with regard to managing the chelation and the anti metastatic effect.
hugs,
pete0 -
I recently found some thatpete43lost_at_sea said:from lef, i just bought 4 normal mcp and 2 chelation mcp
with discounts and free shipping about 48 us dollars per 454g, which is a months supply the way i hammer the stuff, see the link in the other post i did about all the mcp research . it actually blocks the colon cancer receptor.
god i hope this stuff works. so its less the $2 a day or about 50cents per serve
is $12 a week expensive ? i think its reasonable. my doctor almost creamed his pants when he heard i had been on pecta a sol for 14 months. my doctor is going on a conference with the developer and owner of the company. mcp has also won some award for heavy metal chelation.
i am going to get advice directly from the scientist who developed it with regard to managing the chelation and the anti metastatic effect.
hugs,
pete
I recently found some that is different from the last batch I bought. The last jar I purchased had a strong citrus flavour to it, and it was hard to dissolve .... this batch doesn't have the strong citus flavour and mixes much better. We'll see how long this jar lasts me. Hopefully it works!!! Pete I gotta wonder as you mentioned the CV247, and that involves some kind of copper wouldn't the metal chelation you talk about with the MCP affect the copper intake you are using with the CV247???0 -
Pete
I just wanted to add this from the American Cancer Society as there are so many ads for the Chelation therapy that it's hard to find any facts on it. So I just want to toss this in here so that others considering doing this, can see a few other details about chelation not mentioned. I'm not coming out against this, I really couldn't see huge harm in a month or two of it,(with your doctor's knowledge) along with all the high dose vitamins and minerals that are necessary to take at the same time to help mitigate the loss of the good stuff that it takes out with the other minerals, (such as the loss of zinc which your body needs), but then you have the problems with the high dose vitamins and minerals possibly causing cancer, but I think one should first be well armed with the knowledge about the risks involved in taking it (kidney failure, low blood pressure), is why I want to add this for others considering it, as it is difficult to find anything other then the ads after ads after ads for it.
http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/PharmacologicalandBiologicalTreatment/chelation-therapy
Winter Marie0 -
thanks winterherdizziness said:Pete
I just wanted to add this from the American Cancer Society as there are so many ads for the Chelation therapy that it's hard to find any facts on it. So I just want to toss this in here so that others considering doing this, can see a few other details about chelation not mentioned. I'm not coming out against this, I really couldn't see huge harm in a month or two of it,(with your doctor's knowledge) along with all the high dose vitamins and minerals that are necessary to take at the same time to help mitigate the loss of the good stuff that it takes out with the other minerals, (such as the loss of zinc which your body needs), but then you have the problems with the high dose vitamins and minerals possibly causing cancer, but I think one should first be well armed with the knowledge about the risks involved in taking it (kidney failure, low blood pressure), is why I want to add this for others considering it, as it is difficult to find anything other then the ads after ads after ads for it.
http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/PharmacologicalandBiologicalTreatment/chelation-therapy
Winter Marie
the cancer.org warning is fair enough, but its really conventional medicines view which is nice to have here. its refering to edta, i am looking at dmsa, what i discussed above is a derivative of mcp, which is pretty harmless but not as effective. the advocates of mcp claim more effective than edta without sides. i think its dangerous cancer.org has said what it its said.
so the assumption that heavy metal toxicity does cause an environment where cancer grows unchallenged by the bodies defences.
so should i leave the lead, mercury and arsenic in my body ? noway.
but if i followed their advice i would. noway.
as i said earlier somewhere the issue is that some of the world best treatment cancer centers want a clean hair test for heavy metals before they will admit you for treatment. the reasoning to me is clear, heavy metal poinoned patients don't survive.
the responsible apporach to this issue is to say heavy metal poisoning is bad. you should fixed it asap safely. many non toxic ways besides edta. i am not an expert on this and will know alot more after the conference on the weekend about this.
as you said let the buyer beware, as always.
i am just hoping that i am the only one the baord who is getting their heavy metal problem fixed as from what i researched mercury and lead screw your immune system.
when i goggled lead and mercury and immune
i got.
http://www.blacksmithinstitute.org/files/FileUpload/files/Environmental Contaminants and the Immune System.pdf
i found lots of good artlicles and no ads. i was lucky tonight.
so this study clearly shows how bad lead and mercury are for the immune system. now it sounds reasonable from my research. this was just done to prove that vaccines have issues with heavy metal poisoning.
anyone who wants to be a candidate for possible immuno therapy, well should read about the immune system and meavy metal toxity. its an easy and cheap thing to test for and resolve.
all i say is lets give our immune system a chance, that all i am trying to do. its better than folfox or chemo and if it works may help prevent their use.
so hello, our immune system is what protects us against cancer. its at the antigen stage that the battle is fought. i wished my onc warned me about this day one after surgery. maybe i would not be battling a possible recurrence now. this is just my view for my specific case based on my study and clinical history.
your response motivated me to do more research and learning.
thanks for caring.
pursuing health vigorously is my goal, not everyones cup of tea of course. thats the way it should be.
hugs,
pete
ps the answer to all my onc's questions about alternatives is simple.
does the absence of specific double blind clinical trials (evidence based medicine ) preclude commonsense. is pursing health and erring on the safe side not a valid course of action if a patient expresses a desire to do all that is possible to survive. this is my situation and i feel the onc's and the traditional medical establishment are negligent in their duty of care they have to me. sorry but i feel strongly that one day, and that is coming real soon i think the standard cancer treatment offered will be health based not radio/chemo focused.0 -
When you said he almostpete43lost_at_sea said:from lef, i just bought 4 normal mcp and 2 chelation mcp
with discounts and free shipping about 48 us dollars per 454g, which is a months supply the way i hammer the stuff, see the link in the other post i did about all the mcp research . it actually blocks the colon cancer receptor.
god i hope this stuff works. so its less the $2 a day or about 50cents per serve
is $12 a week expensive ? i think its reasonable. my doctor almost creamed his pants when he heard i had been on pecta a sol for 14 months. my doctor is going on a conference with the developer and owner of the company. mcp has also won some award for heavy metal chelation.
i am going to get advice directly from the scientist who developed it with regard to managing the chelation and the anti metastatic effect.
hugs,
pete
When you said he almost creamed his pants what he in favour of MCP or against it. Let us know the outcome of the meeting/confrence0 -
good question about cv247smokeyjoe said:I recently found some that
I recently found some that is different from the last batch I bought. The last jar I purchased had a strong citrus flavour to it, and it was hard to dissolve .... this batch doesn't have the strong citus flavour and mixes much better. We'll see how long this jar lasts me. Hopefully it works!!! Pete I gotta wonder as you mentioned the CV247, and that involves some kind of copper wouldn't the metal chelation you talk about with the MCP affect the copper intake you are using with the CV247???
i will do chelation and get it sorted.
anything i am adding to my regime, i will run past my team. i was just wanting to see if anyone else had experioence with cv247.
i have not check about the chelation coppper issue, i will keep it in the back of my mind.
hugs,
pete0 -
ian rafter my favourite integrative gp loves mcpsmokeyjoe said:When you said he almost
When you said he almost creamed his pants what he in favour of MCP or against it. Let us know the outcome of the meeting/confrence
he knows the developer, he is the doctor thats offered me some sort of a job.
he describes me as his best cancer patient. he is the only doctor that supports some somewhat extreme efforts.
hugs,
Pete0 -
Pete you may want to checkpete43lost_at_sea said:thanks winter
the cancer.org warning is fair enough, but its really conventional medicines view which is nice to have here. its refering to edta, i am looking at dmsa, what i discussed above is a derivative of mcp, which is pretty harmless but not as effective. the advocates of mcp claim more effective than edta without sides. i think its dangerous cancer.org has said what it its said.
so the assumption that heavy metal toxicity does cause an environment where cancer grows unchallenged by the bodies defences.
so should i leave the lead, mercury and arsenic in my body ? noway.
but if i followed their advice i would. noway.
as i said earlier somewhere the issue is that some of the world best treatment cancer centers want a clean hair test for heavy metals before they will admit you for treatment. the reasoning to me is clear, heavy metal poinoned patients don't survive.
the responsible apporach to this issue is to say heavy metal poisoning is bad. you should fixed it asap safely. many non toxic ways besides edta. i am not an expert on this and will know alot more after the conference on the weekend about this.
as you said let the buyer beware, as always.
i am just hoping that i am the only one the baord who is getting their heavy metal problem fixed as from what i researched mercury and lead screw your immune system.
when i goggled lead and mercury and immune
i got.
http://www.blacksmithinstitute.org/files/FileUpload/files/Environmental Contaminants and the Immune System.pdf
i found lots of good artlicles and no ads. i was lucky tonight.
so this study clearly shows how bad lead and mercury are for the immune system. now it sounds reasonable from my research. this was just done to prove that vaccines have issues with heavy metal poisoning.
anyone who wants to be a candidate for possible immuno therapy, well should read about the immune system and meavy metal toxity. its an easy and cheap thing to test for and resolve.
all i say is lets give our immune system a chance, that all i am trying to do. its better than folfox or chemo and if it works may help prevent their use.
so hello, our immune system is what protects us against cancer. its at the antigen stage that the battle is fought. i wished my onc warned me about this day one after surgery. maybe i would not be battling a possible recurrence now. this is just my view for my specific case based on my study and clinical history.
your response motivated me to do more research and learning.
thanks for caring.
pursuing health vigorously is my goal, not everyones cup of tea of course. thats the way it should be.
hugs,
pete
ps the answer to all my onc's questions about alternatives is simple.
does the absence of specific double blind clinical trials (evidence based medicine ) preclude commonsense. is pursing health and erring on the safe side not a valid course of action if a patient expresses a desire to do all that is possible to survive. this is my situation and i feel the onc's and the traditional medical establishment are negligent in their duty of care they have to me. sorry but i feel strongly that one day, and that is coming real soon i think the standard cancer treatment offered will be health based not radio/chemo focused.
Pete you may want to check out The Vitamin C Foundation discussion forum just for curiosity they talk about vitamin C and it's antagonistic affect on copper levels....0 -
Petepete43lost_at_sea said:thanks winter
the cancer.org warning is fair enough, but its really conventional medicines view which is nice to have here. its refering to edta, i am looking at dmsa, what i discussed above is a derivative of mcp, which is pretty harmless but not as effective. the advocates of mcp claim more effective than edta without sides. i think its dangerous cancer.org has said what it its said.
so the assumption that heavy metal toxicity does cause an environment where cancer grows unchallenged by the bodies defences.
so should i leave the lead, mercury and arsenic in my body ? noway.
but if i followed their advice i would. noway.
as i said earlier somewhere the issue is that some of the world best treatment cancer centers want a clean hair test for heavy metals before they will admit you for treatment. the reasoning to me is clear, heavy metal poinoned patients don't survive.
the responsible apporach to this issue is to say heavy metal poisoning is bad. you should fixed it asap safely. many non toxic ways besides edta. i am not an expert on this and will know alot more after the conference on the weekend about this.
as you said let the buyer beware, as always.
i am just hoping that i am the only one the baord who is getting their heavy metal problem fixed as from what i researched mercury and lead screw your immune system.
when i goggled lead and mercury and immune
i got.
http://www.blacksmithinstitute.org/files/FileUpload/files/Environmental Contaminants and the Immune System.pdf
i found lots of good artlicles and no ads. i was lucky tonight.
so this study clearly shows how bad lead and mercury are for the immune system. now it sounds reasonable from my research. this was just done to prove that vaccines have issues with heavy metal poisoning.
anyone who wants to be a candidate for possible immuno therapy, well should read about the immune system and meavy metal toxity. its an easy and cheap thing to test for and resolve.
all i say is lets give our immune system a chance, that all i am trying to do. its better than folfox or chemo and if it works may help prevent their use.
so hello, our immune system is what protects us against cancer. its at the antigen stage that the battle is fought. i wished my onc warned me about this day one after surgery. maybe i would not be battling a possible recurrence now. this is just my view for my specific case based on my study and clinical history.
your response motivated me to do more research and learning.
thanks for caring.
pursuing health vigorously is my goal, not everyones cup of tea of course. thats the way it should be.
hugs,
pete
ps the answer to all my onc's questions about alternatives is simple.
does the absence of specific double blind clinical trials (evidence based medicine ) preclude commonsense. is pursing health and erring on the safe side not a valid course of action if a patient expresses a desire to do all that is possible to survive. this is my situation and i feel the onc's and the traditional medical establishment are negligent in their duty of care they have to me. sorry but i feel strongly that one day, and that is coming real soon i think the standard cancer treatment offered will be health based not radio/chemo focused.
Okay, I'm just worried about too much of it taking away your good minerals away and want you to keep a careful eye on it. Fair enough?
Hugs back,
Winter Marie0 -
thanks winterherdizziness said:Pete
Okay, I'm just worried about too much of it taking away your good minerals away and want you to keep a careful eye on it. Fair enough?
Hugs back,
Winter Marie
thats my worry too, I want to keep my good minerals. particularly zinc. this chelation of heavy metals is scary stuff, but in the context of mcrc well I guess its a managable fear.
chelation can take away the good minerals and most patients regimes try to put them back.
the point of the mcp, is that its supposed to work well with mercury, not so good with lead. but then even this was not unanimous with the experts on this conference panel on chelation.
what works well in clinical practice, thats what counts, and thats what i what out of my doctors.
hugs,
pete0 -
thanks smokeyjoesmokeyjoe said:Pete you may want to check
Pete you may want to check out The Vitamin C Foundation discussion forum just for curiosity they talk about vitamin C and it's antagonistic affect on copper levels....
I will check this out when I get home.
from first principles vit c is a weak chelating agent.
I have read about this as well in a few books i have on minerals by igor.
just too much info to process.
hugs,
pete0 -
so i ordered the chelation complex and have been sent the powder
i am so disappointed as the mcp chelation is the soft option for chelation, at least it is supposed to bind the heavy metals.
I am emailing the ceo of pectasol to see what they think about the difference in effectiveness of the pectasol versus the pectasol chelation product.
http://www.lef.org/magazine/mag2009/mar2009_Modified-Citrus-Pectin-Fighting-Cancer-Metastasis-Heavy-Metal-Toxicities_01.htm?source=search&key=pectasol chelation
Life Extension Magazine March 2009
Fighting Cancer Metastasis and Heavy Metal Toxicities With Modified Citrus Pectin
By Joanne Nicholas
Despite billions of research dollars spent every year, cancer remains the second leading killer of Americans. One reason cancer is so lethal is its tendency to metastasize to essential organs throughout the body.
Certain malignancies (like brain tumors) kill by infiltrating into healthy tissues, but the vast majority of cancer deaths occur when tumor cells enter the blood and lymphatic systems and travel to the liver, lungs, bones, and other distant parts of the body.
Unfortunately, there have been few effective approaches to preventing cancer metastasis. The encouraging news is that a specialized fruit polysaccharide called modified citrus pectin has demonstrated unique properties in blocking cancer cell aggregation, adhesion, and metastasis.1
Clinical research shows that modified citrus pectin helps limit disease progression in men with advanced prostate cancer.2 In addition to its cancer-inhibiting effects, modified citrus pectin shows promise in chelating toxic heavy metals that can be so damaging to overall health.3
Here, we’ll explore how this novel compound offers such distinctive and protective effects.
What is Modified Citrus Pectin?
The American Cancer Society recommends that adults eat five servings of fruits and vegetables each day in order to help reduce cancer risk.4 One way to get some of the benefits of citrus fruits such as oranges and grapefruits is with modified citrus pectin.
Pectin is a naturally occurring substance found in the cell walls of most plants and especially concentrated in the peel and pulp of citrus fruits (lemons, limes, oranges, and grapefruits), plums, and apples. It was first identified in 1825, but home cooks had long used fruits with high levels of pectin in jams and marmalades because of their gelling properties. While pectin provides little nutritional content, this carbohydrate acts as a beneficial type of soluble dietary fiber.
Researchers attempted to find a process to alter pectin to create a food supplement that would allow the body to benefit from its various health-promoting properties. Recently, scientists have been able to use pH and temperature modifications to break down pectin’s long, branched chains of polysaccharides into shorter, unbranched lengths of soluble fiber molecules that dissolve easily in water. The result, modified citrus pectin (MCP), is a substance that is rich in galactose residues, which are easily processed by the digestive system and absorbed into the bloodstream.5 Scientists continue to refine MCP in their quest for a more active and effective agent.
Preventing Cancer Metastasis
Modified citrus pectin is thought to be useful in the prevention and treatment of metastatic cancer, especially in solid tumors like melanoma and cancers of the prostate, colon, and breast. Scientists believe that MCP works by inhibiting two key processes involved in cancer progression: angiogenesis and metastasis.6,7
Angiogenesis is the process in which cancer cells establish their own blood supply to fuel their growth. Metastasis occurs when cancer cells break away from the original tumor, enter the bloodstream or lymphatic system, and form a new tumor in a different organ or other parts of the body.8 Secondary or metastatic cancers often pose more life-threatening circumstances than the original tumor.
As scientists begin to decipher the process of how cells receive, interpret, and relay the signals that recruit them to form new tumors,9 they are focusing their attention on molecules called galactose-binding lectins, or galectins. Galectins are overexpressed adhesion and blood vessel-attracting surface molecules that are thought to be involved in the spread of cancer.6 A growing number of small studies in humans and animals have reported that MCP interferes with the cancer cell’s interactions with other cancer cells by acting as a galectin-3 antagonist—that is, an agent that blocks the normal activity of galectins.
Via the mechanism of galectin-3 antagonism, MCP appears to disrupt the processes that allow cancer cells to communicate with one another. When the MCP molecules bind to receptors on the surface of cancer cells, they block galectin-3 and other molecules from penetrating into nearby healthy tissue to create a new tumor and establish the tumor’s blood supply (angiogenesis). In this way, MCP seems to play a role in preventing cancerous tumors from metastasizing and spreading to other organs—one of the main causes of death from cancer.
When MCP interferes with cancer cells trying to form a new tumor, the cancer cells circulate in the bloodstream until they die. By working to inhibit the spread of cancer, MCP keeps the body’s immune system from becoming overwhelmed by an increasing cancer cell load.10
Modified Citrus Pectin’s Effects in Prostate Cancer
Prostate cancer is the most common cancer diagnosed in men in the United States. One in six American men will be diagnosed with prostate cancer during his lifetime. The American Cancer Society (ACS) estimates that 28,660 men die of prostate cancer annually, with only lung cancer more lethal to men.11 The ACS estimates a five-year survival rate of nearly 100% for men whose prostate cancer is diagnosed and treated at an early stage. But for those men with late stage, metastatic prostate cancer, the treatment options are very limited.
One of the first promising studies to show the potential of MCP to inhibit prostate cancer metastasis was published in the Journal of the National Cancer Institute in 1995. Laboratory rats were injected with human prostate cancer cells and divided into four groups. The control group received plain water and the other groups received water with varying concentrations of MCP. After 30 days, only 50% of the rats that drank water with MCP (0.1% weight/volume) had any metastases, while 94% of the rats that drank regular water had cancer metastasize to their lungs. The researchers called for further study to determine both “the role of galectin-3 in normal and cancerous prostate tissues” and “the ability of modified citrus pectin to inhibit human prostate metastasis in nude mice.”12
In 1999, Dr. Stephen Strum, an oncologist specializing in prostate cancer and a respected member of Life Extension’s Scientific Advisory Board, and his colleagues were the first to show the positive effects of MCP on humans with advanced prostate cancer. In a paper presented at an International Conference on Diet and Prevention of Cancer, they reported that five of seven men with advanced prostate cancer and unable to benefit from conventional treatment had a positive response after taking MCP every day for three months or longer. The response was measured by an increase in prostate-specific antigen doubling time (PSADT), which measures the rate at which blood levels of prostate-specific antigen (PSA) rise. Since PSA is a marker of prostate cancer progression or recurrence, longer PSA doubling time is associated with slower disease progression and is thus desirable. One of the five patients had no increase to his PSA level at all.13
A more recent study led by Brad Guess and Drs. Mark Scholz and Stephen Strum also found that MCP increases the PSA doubling time. In this phase II pilot study of 10 men whose prostate cancer had returned after an initial treatment with surgery or radiation, PSADT increased in eight (80%) of the 10 men after taking MCP for 12 months.14
Dr. Strum told Life Extension, “My clinical experience using MCP in prostate cancer has been that it slows PSA doubling time in the majority of patients taking the standard dose of 5 grams three times per day. Because this treatment is well tolerated, I use MCP in situations where sustained increases in PSA may occur.” In a study published in 2007, 49 patients with advanced prostate cancer and few treatment options were given oral doses of MCP powder diluted in water and juice three times a day at eight-hour intervals for a four-week cycle. After two cycles of treatment with MCP, 21% of the patients had a clinical benefit of disease stabilization or improved quality of life; 12% had stable disease for more than 24 weeks. One patient with stage IV metastatic prostate cancer showed a 50% decrease in serum PSA level after 16 weeks of treatment, improving his quality of life and also decreasing pain. “MCP seems to have positive impacts especially regarding clinical benefit and life quality for patients with far advanced solid tumors,” the researchers concluded.2
WHAT YOU NEED TO KNOW: MODIFIED CITRUS PECTIN
Pectin is a complex carbohydrate that is abundantly present in citrus fruits. Modified citrus pectin (MCP) is composed of short, non-branched carbohydrate chains derived from the peel and pulp of citrus fruits.
Compelling research suggests that modified citrus pectin may help block the growth and metastasis of solid tumors such as breast, colon, and prostate cancers.
Intriguing clinical studies suggest that supplementation with MCP stabilizes disease progression and lengthens PSA doubling times in men with prostate cancer.
Modified citrus pectin may represent a safe, non-toxic d of chelating toxic metals—without the need for intravenous infusions.
Supplementation with MCP has been shown to increase excretion of dangerous metals such as mercury, arsenic, lead, and cadmium—without removing essential minerals like calcium, magnesium, and zinc from the body.
A clinical study showed that supplementation with an MCP-alginate complex reduced total body toxic heavy metal burden in patients with a variety of health concerns.
MCP is considered safe and well tolerated. Dosages range from 6 to 30 grams per day in divided dosages; a typical dose is 5 grams three times daily.
Modified Citrus Pectin and Chelation
Beyond its benefits in fighting cancer metastasis, MCP may have applications in mitigating the health dangers posed by toxic heavy metals. Chelation therapy is a chemical process in which a substance is used to bind molecules, such as heavy metals or minerals, and hold them tightly so that they can be removed from a system, such as the body. Chelation can help rid the body of excess or toxic metals, but it is not known if this reduces artery disease risk. Chelation is used to treat lead and mercury poisoning.15,16
In most instances, chelation therapy involves the infusion of compounds via a catheter placed in an arm vein. This procedure must be done in a clinical setting over a specified course of treatments. In contrast, chelation therapy using MCP is done via the oral route and can be administered to the patient in almost any clinical setting, since the supplement can be ingested anywhere.
A pilot trial evaluating MCP’s chelating effects provided evidence that orally administered MCP significantly increases urinary excretion of toxic metals. In a study published in 2006, eight healthy individuals were given 15 grams of MCP daily for five days and 20 grams of MCP on day six. Twenty-four hour urine samples were collected on days one and six and analyzed for toxic and essential elements. The investigators reported that significant urinary excretion of arsenic, mercury, cadmium, and lead increased within one to six days of MCP treatment. There was a 150% increase in the excretion of cadmium and a 560% increase in lead excretion on day six.3 Essential minerals such as calcium, zinc, and magnesium were not seen to increase in the urine analysis, indicating that MCP treatment did not deplete these nutrients.
In a case study report, five patients with different illnesses were given MCP (PectaSol®) alone or as an MCP/alginate combination (PectaSol® Chelation Complex™) for up to seven months. Each one had a gradual decrease of total heavy metal burden, which is believed to have played an important role in the patients’ recovery and health maintenance. The patients had a 74% average decrease in toxic heavy metals after treatment. The authors report this is the “first known documentation of evidence” of a possible correlation of positive clinical outcomes and a reduction of toxic heavy metal load using MCP alone or as an MCP/alginate complex. They recommend “further studies be performed to confirm the effectiveness of this gentle non-toxic chelating system as an alternative to harsher chelators in the treatment of patients with a heavy metal body burden.”17
Lead toxicity is an ongoing concern worldwide, and the long-lasting effects of lead exposure in children are especially troubling. A 2008 pilot study at the Children’s Hospital of Zhejiang University, Hangzhou, China looked at whether MCP® could mitigate lead toxicity in children with high blood levels of lead. Seven children hospitalized with toxic lead levels, aged five to 12, were given 15 grams of MCP (PectaSol®) per day in three divided dosages. Blood serum and 24-hour urine excretion analysis were performed on days 0, 14, 21, and 28. Two patients were released after two weeks, three patients were released after three weeks, and two patients were released after four weeks when their blood lead levels had dropped below the criterion. All of the children had a significant increase in urinary excretion of lead. The authors recommend further studies to confirm the effectiveness and safety of MCP as a lead chelator.18
Scientists believe that the ability of MCP (PectaSol®) to chelate toxic metals arises from a low molecular weight pectin that contains 10% rhamnogalacturonan II molecular side groups, which are known to selectively bind heavy metals with a strong affinity. Subsequently, these metal–pectin complexes are eliminated in the urine.30 -
MCPherdizziness said:Pete
I just wanted to add this from the American Cancer Society as there are so many ads for the Chelation therapy that it's hard to find any facts on it. So I just want to toss this in here so that others considering doing this, can see a few other details about chelation not mentioned. I'm not coming out against this, I really couldn't see huge harm in a month or two of it,(with your doctor's knowledge) along with all the high dose vitamins and minerals that are necessary to take at the same time to help mitigate the loss of the good stuff that it takes out with the other minerals, (such as the loss of zinc which your body needs), but then you have the problems with the high dose vitamins and minerals possibly causing cancer, but I think one should first be well armed with the knowledge about the risks involved in taking it (kidney failure, low blood pressure), is why I want to add this for others considering it, as it is difficult to find anything other then the ads after ads after ads for it.
http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/PharmacologicalandBiologicalTreatment/chelation-therapy
Winter Marie
Hi Winter...
That link was about traditional chelation therapy - and YES, it does have a "down" side. it can remove minerals the body needs. It also is expensive and there is a problem with reabsorption. That is why MCP - modified citrus pectin ROCKS! It absolutely cannot hurt you... it has no side effects and it removes aluminum, arsenic, cadmium, lead and mercury. It took Dr. Isaac Eliaz a couple of years to work out the reabsorption problem (MCP binds to heavy metals but they would get reabsorbed before complete flushing from body), until he figured out how to combine it with an alginate from kelp.
Here is a YouTube video (part 2 of 3 parts) of a TV show called The Incurables that features Dr. Eliaz and a patient he cured using, in part, MCP.
http://www.youtube.com/watch?v=CmQDBQJJbh8
The MOLECULAR weight of the MCP is very important - not all MCP is created equal. If the weight is too high, or too low, it will not be as effective. However since Dr. Eliaz is the developer of MCP you can get it directly from his website and KNOW you are getting the same stuff they are using in these clinical studies and scientific research trials. You can also get Dr. Eliaz's MCP formula as part of a three part system called Qore, from a company called Qivana. Dr. Eliaz licensed his MCP formula to them as the "detox" part of their all natural system designed to address your CORE health - immunity, inflammation and detoxification.
MCP is cheap compared to drugs... and frankly, when it comes to cancer.... I'd be attacking it on all fronts... MCP, Qore, Alkaline water, anti-inflammatory foods, signaling molecules (nitric oxide for one), anything that boosts immunity and cellular health. Ridding the body of inflammation is also critical because inflammation prevents essential circulation.
Dr. Eliaz is the LEADING integrative physician in the country - one of the top in the world. He is the ONLY integrative physician ever invited to speak to top Oncologists at the American Cancer Societies "TigerLily" Foundation. This indicates a major "shift" in thinking toward a more holistic approach toward cancer treatment. http://www.globenewswire.com/newsroom/news.html?d=232933
MCP actually works 3 ways on cancer....
1) by wrapping the cancer cell (cancer is attracted to MCP which is a long chain sugar molecule), and preventing the cell from attaching to anything else so that it just dies off.
2) by detoxing the body of heavy metals - a leading contributor to cancer. As Dr. Eliaz says... if you don't detox from the heavy metals it's almost impossible to cure a metastatic cancer.
3) by inhibiting Glactin-3 - and forgive me, I'm not sure the exact role Glactin-3 plays in cancer - but apparently it does and there are several scientific studies you can find online.
Keep in mind that even Dr. Eliaz (who has cured many, many people of cancer) will tell you there is no SINGLE natural thing that will cure cancer by itself. However when you combine different things together - it seems like you can overwhelm the cancer and allow your body to heal itself. It starts with a heathy immune system and detoxification. Then you certainly need to pay close attention to what you put in your body. More and more Doctors are combining "natural" cancer treatments with the "chemical" ones and getting great results. Naturopaths will do only natural treatments and also get good results. However we ALL have to do our own research and make our own (informed) decision of what we want to do with our bodies.
I hope this helps... and you can Google Dr. Isaac Eliaz and MCP - Modified Citrus Pectin and find all kinds of scientific studies that have been done... certainly enough to give everyone confidence in knowing it is certainly worth trying.0 -
Difference between PectaSol and the Chelation compound.pete43lost_at_sea said:so i ordered the chelation complex and have been sent the powder
i am so disappointed as the mcp chelation is the soft option for chelation, at least it is supposed to bind the heavy metals.
I am emailing the ceo of pectasol to see what they think about the difference in effectiveness of the pectasol versus the pectasol chelation product.
http://www.lef.org/magazine/mag2009/mar2009_Modified-Citrus-Pectin-Fighting-Cancer-Metastasis-Heavy-Metal-Toxicities_01.htm?source=search&key=pectasol chelation
Life Extension Magazine March 2009
Fighting Cancer Metastasis and Heavy Metal Toxicities With Modified Citrus Pectin
By Joanne Nicholas
Despite billions of research dollars spent every year, cancer remains the second leading killer of Americans. One reason cancer is so lethal is its tendency to metastasize to essential organs throughout the body.
Certain malignancies (like brain tumors) kill by infiltrating into healthy tissues, but the vast majority of cancer deaths occur when tumor cells enter the blood and lymphatic systems and travel to the liver, lungs, bones, and other distant parts of the body.
Unfortunately, there have been few effective approaches to preventing cancer metastasis. The encouraging news is that a specialized fruit polysaccharide called modified citrus pectin has demonstrated unique properties in blocking cancer cell aggregation, adhesion, and metastasis.1
Clinical research shows that modified citrus pectin helps limit disease progression in men with advanced prostate cancer.2 In addition to its cancer-inhibiting effects, modified citrus pectin shows promise in chelating toxic heavy metals that can be so damaging to overall health.3
Here, we’ll explore how this novel compound offers such distinctive and protective effects.
What is Modified Citrus Pectin?
The American Cancer Society recommends that adults eat five servings of fruits and vegetables each day in order to help reduce cancer risk.4 One way to get some of the benefits of citrus fruits such as oranges and grapefruits is with modified citrus pectin.
Pectin is a naturally occurring substance found in the cell walls of most plants and especially concentrated in the peel and pulp of citrus fruits (lemons, limes, oranges, and grapefruits), plums, and apples. It was first identified in 1825, but home cooks had long used fruits with high levels of pectin in jams and marmalades because of their gelling properties. While pectin provides little nutritional content, this carbohydrate acts as a beneficial type of soluble dietary fiber.
Researchers attempted to find a process to alter pectin to create a food supplement that would allow the body to benefit from its various health-promoting properties. Recently, scientists have been able to use pH and temperature modifications to break down pectin’s long, branched chains of polysaccharides into shorter, unbranched lengths of soluble fiber molecules that dissolve easily in water. The result, modified citrus pectin (MCP), is a substance that is rich in galactose residues, which are easily processed by the digestive system and absorbed into the bloodstream.5 Scientists continue to refine MCP in their quest for a more active and effective agent.
Preventing Cancer Metastasis
Modified citrus pectin is thought to be useful in the prevention and treatment of metastatic cancer, especially in solid tumors like melanoma and cancers of the prostate, colon, and breast. Scientists believe that MCP works by inhibiting two key processes involved in cancer progression: angiogenesis and metastasis.6,7
Angiogenesis is the process in which cancer cells establish their own blood supply to fuel their growth. Metastasis occurs when cancer cells break away from the original tumor, enter the bloodstream or lymphatic system, and form a new tumor in a different organ or other parts of the body.8 Secondary or metastatic cancers often pose more life-threatening circumstances than the original tumor.
As scientists begin to decipher the process of how cells receive, interpret, and relay the signals that recruit them to form new tumors,9 they are focusing their attention on molecules called galactose-binding lectins, or galectins. Galectins are overexpressed adhesion and blood vessel-attracting surface molecules that are thought to be involved in the spread of cancer.6 A growing number of small studies in humans and animals have reported that MCP interferes with the cancer cell’s interactions with other cancer cells by acting as a galectin-3 antagonist—that is, an agent that blocks the normal activity of galectins.
Via the mechanism of galectin-3 antagonism, MCP appears to disrupt the processes that allow cancer cells to communicate with one another. When the MCP molecules bind to receptors on the surface of cancer cells, they block galectin-3 and other molecules from penetrating into nearby healthy tissue to create a new tumor and establish the tumor’s blood supply (angiogenesis). In this way, MCP seems to play a role in preventing cancerous tumors from metastasizing and spreading to other organs—one of the main causes of death from cancer.
When MCP interferes with cancer cells trying to form a new tumor, the cancer cells circulate in the bloodstream until they die. By working to inhibit the spread of cancer, MCP keeps the body’s immune system from becoming overwhelmed by an increasing cancer cell load.10
Modified Citrus Pectin’s Effects in Prostate Cancer
Prostate cancer is the most common cancer diagnosed in men in the United States. One in six American men will be diagnosed with prostate cancer during his lifetime. The American Cancer Society (ACS) estimates that 28,660 men die of prostate cancer annually, with only lung cancer more lethal to men.11 The ACS estimates a five-year survival rate of nearly 100% for men whose prostate cancer is diagnosed and treated at an early stage. But for those men with late stage, metastatic prostate cancer, the treatment options are very limited.
One of the first promising studies to show the potential of MCP to inhibit prostate cancer metastasis was published in the Journal of the National Cancer Institute in 1995. Laboratory rats were injected with human prostate cancer cells and divided into four groups. The control group received plain water and the other groups received water with varying concentrations of MCP. After 30 days, only 50% of the rats that drank water with MCP (0.1% weight/volume) had any metastases, while 94% of the rats that drank regular water had cancer metastasize to their lungs. The researchers called for further study to determine both “the role of galectin-3 in normal and cancerous prostate tissues” and “the ability of modified citrus pectin to inhibit human prostate metastasis in nude mice.”12
In 1999, Dr. Stephen Strum, an oncologist specializing in prostate cancer and a respected member of Life Extension’s Scientific Advisory Board, and his colleagues were the first to show the positive effects of MCP on humans with advanced prostate cancer. In a paper presented at an International Conference on Diet and Prevention of Cancer, they reported that five of seven men with advanced prostate cancer and unable to benefit from conventional treatment had a positive response after taking MCP every day for three months or longer. The response was measured by an increase in prostate-specific antigen doubling time (PSADT), which measures the rate at which blood levels of prostate-specific antigen (PSA) rise. Since PSA is a marker of prostate cancer progression or recurrence, longer PSA doubling time is associated with slower disease progression and is thus desirable. One of the five patients had no increase to his PSA level at all.13
A more recent study led by Brad Guess and Drs. Mark Scholz and Stephen Strum also found that MCP increases the PSA doubling time. In this phase II pilot study of 10 men whose prostate cancer had returned after an initial treatment with surgery or radiation, PSADT increased in eight (80%) of the 10 men after taking MCP for 12 months.14
Dr. Strum told Life Extension, “My clinical experience using MCP in prostate cancer has been that it slows PSA doubling time in the majority of patients taking the standard dose of 5 grams three times per day. Because this treatment is well tolerated, I use MCP in situations where sustained increases in PSA may occur.” In a study published in 2007, 49 patients with advanced prostate cancer and few treatment options were given oral doses of MCP powder diluted in water and juice three times a day at eight-hour intervals for a four-week cycle. After two cycles of treatment with MCP, 21% of the patients had a clinical benefit of disease stabilization or improved quality of life; 12% had stable disease for more than 24 weeks. One patient with stage IV metastatic prostate cancer showed a 50% decrease in serum PSA level after 16 weeks of treatment, improving his quality of life and also decreasing pain. “MCP seems to have positive impacts especially regarding clinical benefit and life quality for patients with far advanced solid tumors,” the researchers concluded.2
WHAT YOU NEED TO KNOW: MODIFIED CITRUS PECTIN
Pectin is a complex carbohydrate that is abundantly present in citrus fruits. Modified citrus pectin (MCP) is composed of short, non-branched carbohydrate chains derived from the peel and pulp of citrus fruits.
Compelling research suggests that modified citrus pectin may help block the growth and metastasis of solid tumors such as breast, colon, and prostate cancers.
Intriguing clinical studies suggest that supplementation with MCP stabilizes disease progression and lengthens PSA doubling times in men with prostate cancer.
Modified citrus pectin may represent a safe, non-toxic d of chelating toxic metals—without the need for intravenous infusions.
Supplementation with MCP has been shown to increase excretion of dangerous metals such as mercury, arsenic, lead, and cadmium—without removing essential minerals like calcium, magnesium, and zinc from the body.
A clinical study showed that supplementation with an MCP-alginate complex reduced total body toxic heavy metal burden in patients with a variety of health concerns.
MCP is considered safe and well tolerated. Dosages range from 6 to 30 grams per day in divided dosages; a typical dose is 5 grams three times daily.
Modified Citrus Pectin and Chelation
Beyond its benefits in fighting cancer metastasis, MCP may have applications in mitigating the health dangers posed by toxic heavy metals. Chelation therapy is a chemical process in which a substance is used to bind molecules, such as heavy metals or minerals, and hold them tightly so that they can be removed from a system, such as the body. Chelation can help rid the body of excess or toxic metals, but it is not known if this reduces artery disease risk. Chelation is used to treat lead and mercury poisoning.15,16
In most instances, chelation therapy involves the infusion of compounds via a catheter placed in an arm vein. This procedure must be done in a clinical setting over a specified course of treatments. In contrast, chelation therapy using MCP is done via the oral route and can be administered to the patient in almost any clinical setting, since the supplement can be ingested anywhere.
A pilot trial evaluating MCP’s chelating effects provided evidence that orally administered MCP significantly increases urinary excretion of toxic metals. In a study published in 2006, eight healthy individuals were given 15 grams of MCP daily for five days and 20 grams of MCP on day six. Twenty-four hour urine samples were collected on days one and six and analyzed for toxic and essential elements. The investigators reported that significant urinary excretion of arsenic, mercury, cadmium, and lead increased within one to six days of MCP treatment. There was a 150% increase in the excretion of cadmium and a 560% increase in lead excretion on day six.3 Essential minerals such as calcium, zinc, and magnesium were not seen to increase in the urine analysis, indicating that MCP treatment did not deplete these nutrients.
In a case study report, five patients with different illnesses were given MCP (PectaSol®) alone or as an MCP/alginate combination (PectaSol® Chelation Complex™) for up to seven months. Each one had a gradual decrease of total heavy metal burden, which is believed to have played an important role in the patients’ recovery and health maintenance. The patients had a 74% average decrease in toxic heavy metals after treatment. The authors report this is the “first known documentation of evidence” of a possible correlation of positive clinical outcomes and a reduction of toxic heavy metal load using MCP alone or as an MCP/alginate complex. They recommend “further studies be performed to confirm the effectiveness of this gentle non-toxic chelating system as an alternative to harsher chelators in the treatment of patients with a heavy metal body burden.”17
Lead toxicity is an ongoing concern worldwide, and the long-lasting effects of lead exposure in children are especially troubling. A 2008 pilot study at the Children’s Hospital of Zhejiang University, Hangzhou, China looked at whether MCP® could mitigate lead toxicity in children with high blood levels of lead. Seven children hospitalized with toxic lead levels, aged five to 12, were given 15 grams of MCP (PectaSol®) per day in three divided dosages. Blood serum and 24-hour urine excretion analysis were performed on days 0, 14, 21, and 28. Two patients were released after two weeks, three patients were released after three weeks, and two patients were released after four weeks when their blood lead levels had dropped below the criterion. All of the children had a significant increase in urinary excretion of lead. The authors recommend further studies to confirm the effectiveness and safety of MCP as a lead chelator.18
Scientists believe that the ability of MCP (PectaSol®) to chelate toxic metals arises from a low molecular weight pectin that contains 10% rhamnogalacturonan II molecular side groups, which are known to selectively bind heavy metals with a strong affinity. Subsequently, these metal–pectin complexes are eliminated in the urine.3
Hope this helps.... the difference between PectaSol and the chelation compound is simply that the chelation formula has the MCP combined with an alginate from kelp. The reason for this is because the alginate prevents the reabsorption into the body after the MCP has combined with a heavy metal (thus allowing the body to fully flush it out).
For fighting cancer cells... it doesn't need alginate to work (this is the PectaSol C). Frankly... If I had active cancer (or was a recent survivor) I would take BOTH formulas. I'd do the chelation one for two months... then do it every 2-3 months for a month to detox from the metals on a regular basis. But I'd do the PectaSol ALL THE TIME to prevent/slow metastasis.
By the way... detoxing from heavy metals should be done regularly. You get heavy metals from a lot of sources - including the gallon and a half of pesticides we consume each year though our food supply, automobile exhaust, cigarette smoke (even second hand), and some processed cereals (be careful of all processed food - especially meats).
metal in cereal
http://www.youtube.com/watch?v=5ahlawrQHeA&
processed meats - don't touch them!
http://naturalhealthdossier.com/2012/04/processed-meats-declared-too-dangerous-for-human-consumption/
To your long and healthy life!0 -
thanks sueSueJC said:Difference between PectaSol and the Chelation compound.
Hope this helps.... the difference between PectaSol and the chelation compound is simply that the chelation formula has the MCP combined with an alginate from kelp. The reason for this is because the alginate prevents the reabsorption into the body after the MCP has combined with a heavy metal (thus allowing the body to fully flush it out).
For fighting cancer cells... it doesn't need alginate to work (this is the PectaSol C). Frankly... If I had active cancer (or was a recent survivor) I would take BOTH formulas. I'd do the chelation one for two months... then do it every 2-3 months for a month to detox from the metals on a regular basis. But I'd do the PectaSol ALL THE TIME to prevent/slow metastasis.
By the way... detoxing from heavy metals should be done regularly. You get heavy metals from a lot of sources - including the gallon and a half of pesticides we consume each year though our food supply, automobile exhaust, cigarette smoke (even second hand), and some processed cereals (be careful of all processed food - especially meats).
metal in cereal
http://www.youtube.com/watch?v=5ahlawrQHeA&
processed meats - don't touch them!
http://naturalhealthdossier.com/2012/04/processed-meats-declared-too-dangerous-for-human-consumption/
To your long and healthy life!
Of course to our long and healthy lives,
but they are built one great moment by moment, day by day.
your kind input is appreciated, i am findling with many chelation bits and pieces.
i will be really peived if the mcp binds them and they get reabsorbed.
i have bucket loads of mcp, i shoudl find the alginate as a powder and do it myself.
i have tried some colonics, ouch!, some sauna infa red, got some bendonite clay and been having kelp caps mainly for iodine, but i think they have alginate as well.
i live in sydney and before cancer, i used to dive with many of these forms of seeweed.
http://www.fao.org/docrep/006/y4765e/y4765e07.htm
one day soon i will collect some buckets of this weed, dry it , mill it and use it.
at some beaches up the coast tons of brown kelp are washed up after storms, enough to detox most of sydney, and its all washed back to sea. how sad.
the mcp/alginate caps are really expensive from lef or ebay.
i also have humic acid to stop the reabsorption problem but have been saving it for full on detox , but this is waiting on excellent mineral status that i just cannot reach.
if you see my blog, i went to a doctors conference on toxins, one whole day was heavy metals and all the chelation forms were discussed.
lots of opinions on this area, little consesus in alternative circles so i am trending carefully. i have trusted my gut and my research and tried colonics and had my **** burned figuratively speaking. actually i still need nappies as my gut and bowel habits have not settled since having 6 colonics over 6 weeks. i live and learn.
i am religios about my mcp, sincerely appreciate your support re its use. not many here on csn are into it. do you have any new info confirming hopw good it is, been on it for 18 months, hardcore for 8 months.
ie 2 teaspoons 3 times daily with broccoli powder and other goodies.
hugs,
pete0 -
Dr. Eliaz
Dr. Eliaz says MCP can be mixed in water or juices. I could not tolerate the taste in water or tea but found a very watery applesauce works very well. I mix my MCP and my homemade/ all natural applesauce and allow it to sit for about 5 minutes.
Dr. Eliaz recommends 5 gr 3 X a day for those with known active cancer and 5 gr a day for maintenance. I take 5 gr every a.m. 5 gr is a heaping tsp.
The Importance of Modified Citrus Pectin
Isaac Eliaz, M.D., M.S., L.Ac.
Medical Director, Amitabha Medical Clinic
Effects of daily oral administration of quercetin chalcone and modified citrus pectin on implanted colon-25 tumor growth in Balb-c mice.
The health benefits of fruits and vegetables have been the subject of numerous investigations over many years. Two natural substances, quercetin (a flavonoid) and citrus pectin (a polysaccharide found in the cell wall of plants) are of particular interest to cancer researchers. Two modified versions of these substances - quercetin chalcone (QC) and a pH-modified citrus pectin (MCP) - are the focus of this study. Previous research has confirmed that quercetin exhibits antitumor properties, likely due to immune stimulation, free radical scavenging, alteration of the mitotic cycle in tumor cells, gene expression modification, anti-angiogenesis activity, or apoptosis induction, or a combination of these effects. MCP has inhibited metastases in animal studies of prostate cancer and melanoma. To date, no study has demonstrated a reduction in solid tumor growth with MCP, and there is no research into the antitumor effect of QC. This study examines the effects of MCP and QC on the size and weight of colon-25 tumors implanted in balb-c mice. Fifty mice were orally administered either 1 ml distilled water (controls), low-dose QC (0.8 mg/ml), high-dose QC (1.6 mg/ml), low-dose MCP (0. 8 mg/ml) or high-dose MCP (1.6 mg/ml) on a daily basis, beginning the first day of tumor palpation (usually eight days post-implantation). A significant reduction in tumor size was noted at day 20 in all groups compared to controls. The groups given low-dose QC and MCP had a 29% (NS) and 38% (p<0.02) decrease in size, respectively. The high-dose groups had an even more impressive reduction in size; 65% in the QC group and 70% in the mice given MCP (both p<0.001). This is the first evidence that MCP can reduce the growth of solid primary tumors, and the first research showing QC has antitumor activity. Additional research on these substances and their effect on human cancers is warranted.
Altern Med Rev. 2000 Dec;5(6):546-52
Expression of galectin-3 in liver metastasis of colon cancer and the inhibitory effect of modified citrus pectin.
CONCLUSION: The expression of galetin-3 is significantly increased in the liver metastasis of colon cancer, and MCP can effectively inhibit the liver metastasis.
Nan Fang Yi Ke Da Xue Xue Bao. 2008 Aug;28(8):1358-60 -
thanks patchPatchAdams said:Dr. Eliaz
Dr. Eliaz says MCP can be mixed in water or juices. I could not tolerate the taste in water or tea but found a very watery applesauce works very well. I mix my MCP and my homemade/ all natural applesauce and allow it to sit for about 5 minutes.
Dr. Eliaz recommends 5 gr 3 X a day for those with known active cancer and 5 gr a day for maintenance. I take 5 gr every a.m. 5 gr is a heaping tsp.
The Importance of Modified Citrus Pectin
Isaac Eliaz, M.D., M.S., L.Ac.
Medical Director, Amitabha Medical Clinic
Effects of daily oral administration of quercetin chalcone and modified citrus pectin on implanted colon-25 tumor growth in Balb-c mice.
The health benefits of fruits and vegetables have been the subject of numerous investigations over many years. Two natural substances, quercetin (a flavonoid) and citrus pectin (a polysaccharide found in the cell wall of plants) are of particular interest to cancer researchers. Two modified versions of these substances - quercetin chalcone (QC) and a pH-modified citrus pectin (MCP) - are the focus of this study. Previous research has confirmed that quercetin exhibits antitumor properties, likely due to immune stimulation, free radical scavenging, alteration of the mitotic cycle in tumor cells, gene expression modification, anti-angiogenesis activity, or apoptosis induction, or a combination of these effects. MCP has inhibited metastases in animal studies of prostate cancer and melanoma. To date, no study has demonstrated a reduction in solid tumor growth with MCP, and there is no research into the antitumor effect of QC. This study examines the effects of MCP and QC on the size and weight of colon-25 tumors implanted in balb-c mice. Fifty mice were orally administered either 1 ml distilled water (controls), low-dose QC (0.8 mg/ml), high-dose QC (1.6 mg/ml), low-dose MCP (0. 8 mg/ml) or high-dose MCP (1.6 mg/ml) on a daily basis, beginning the first day of tumor palpation (usually eight days post-implantation). A significant reduction in tumor size was noted at day 20 in all groups compared to controls. The groups given low-dose QC and MCP had a 29% (NS) and 38% (p<0.02) decrease in size, respectively. The high-dose groups had an even more impressive reduction in size; 65% in the QC group and 70% in the mice given MCP (both p<0.001). This is the first evidence that MCP can reduce the growth of solid primary tumors, and the first research showing QC has antitumor activity. Additional research on these substances and their effect on human cancers is warranted.
Altern Med Rev. 2000 Dec;5(6):546-52
Expression of galectin-3 in liver metastasis of colon cancer and the inhibitory effect of modified citrus pectin.
CONCLUSION: The expression of galetin-3 is significantly increased in the liver metastasis of colon cancer, and MCP can effectively inhibit the liver metastasis.
Nan Fang Yi Ke Da Xue Xue Bao. 2008 Aug;28(8):1358-6</p>
i will keep on taking my foul tasting mcp, but i love, i know its good for me.
thanks for the study, i am hammering quercetin, source naturals activated 3 pills breakfast lunch and dinner. except i had a break for a month from quercetin and my markers went from 30 to 46 in a month. but other changes to my protocol occurred.
tonight i had purple soup, hash purples. purple onions, they call them spanish here, a good source of quercetin. trying to get these goodies naturally where p;ossible.
its nice to see some of these recommendations from the past get bought back, we always get newcomers to this board and they don't see all the interesting alternatives i discussed over the last 19 months.
i have never had of the QC chalone, i will check it out.
hugs,
pete
ps love your name, one of my favourite comedies. and i think it says something about the medical system to boot.0 -
Pete - how did you get heavy
Pete - how did you get heavy metal poisoning? I never heard this before. Thanks - I want to talk to my Onc abouth this.0 -
FOLFOXmarbleotis said:Pete - how did you get heavy
Pete - how did you get heavy metal poisoning? I never heard this before. Thanks - I want to talk to my Onc abouth this.
possibly Folfox - the 'ox" referes to oxaliplatin which contains platinum.0
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