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aspirin and breast cancer

Medical Writer: William Yarnall, RPh, CCP
Expert Faculty: Lisa A. Carey, MD, ScM
Clinical Insights
• Aspirin use post-breast cancer diagnosis may prolong life and reduce the risk of distant recurrence in some breast cancer patients
• Randomized, controlled trials are needed to confirm the beneficial effect of aspirin and NSAIDs in reducing morbidity and mortality in breast cancer patients
In vitro studies have shown that breast cancer cells produce more prostaglandins than normal cells, and animal studies have demonstrated increased cyclooxygenase-2 (COX-2) activity in metastatic breast cancer. Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDS) are prostaglandin and COX inhibitors and are also known to augment immune responsiveness and suppress cytokines that stimulate bony metastases. Therefore, it has been suggested that these drugs may increase survival among women with breast cancer by decreasing the growth and invasiveness of breast cancer cells. In order to investigate the possibility that aspirin use post-diagnosis might be associated with decreased risk of breast cancer death and distant recurrence, this was examined among Nurses' Health Study (NHS) subjects who developed stage I-III breast cancer.
http://tinyurl.com/2ajp
Comments
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Thanks for the information.
Thanks for the information. I just spoke to my doc today about it and I'll be starting soon. This article talks about taking it 2-5 days/wk and having better results than everyday. I think that's what I'm going to do. Maybe every other day. It's good to check it out as it appears the benefit is significant.
Aspirin Could Lower Chance Of Breast Cancer Recurrence, Death, Study Finds -
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Never ... EVER heard of this .. THANK YOUBella Luna said:Yes, my oncologist suggested
Yes, my oncologist suggested I take aspirin, too. I am taking Low Dose Bayer aspirin, one tablet(81mg) a day. I started taking it after finishing up with radiation.
BL
for this posting ...
Vicki Sam -
did the sameBella Luna said:Yes, my oncologist suggested
Yes, my oncologist suggested I take aspirin, too. I am taking Low Dose Bayer aspirin, one tablet(81mg) a day. I started taking it after finishing up with radiation.
BL
Yes I take baby /low dose a day..I thought perhaps for blood clots-did not realize why I was to take it. When I go back I ask..SHOULD keep taking baby asprin? YES is the reply... -
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