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Xeloda questions

abrub's picture
abrub
Posts: 2130
Joined: Mar 2010

Because my scans were good (YAY!!) my chemo is being changed from Folfiri plus Avastin to Xeloda plus Avastin, with Xeloda one week on; one week off (as opposed to the traditional 2 weeks on, 1 week off) and Avastin every 3 weeks.

Any thoughts, anything I should know?  Xeloda scares me a bit, as I am terrified of nausea and vomiting, and I don't know if there is a greater likelihood on the pill form.

Thanks in advance for any advice.

Alice

 

Tunadog's picture
Tunadog
Posts: 235
Joined: Mar 2017

I've been on Xyloda and Avastin for 4 years.

No issues 

 

suzycruise76's picture
suzycruise76
Posts: 125
Joined: Mar 2019

I was on Xeloda for 25 days combined with radiation (5 days a week,weekends off). My hospital gave me pills to take if nausea strikes-it never happened,so,I was lucky. Not even one day vomiting or feeling nauseaus. BUT: I lost my appetite the first day I took Xeloda; suddenly every food-even my most favorite-stopped being appetizing;I just didn't feel like eating at all. I knew that nurishment is important before surgery, so I made myself to eat small portions of food that looked at least a bit acceptable.

There are some other side effects with Xeloda,but everybody is different,so it is hard to tell what to expect.

Hope you are not going to have it too difficult.

Suzy

AnneO1965's picture
AnneO1965
Posts: 148
Joined: May 2019

I did 28 days of Xeloda and radiation, not a single bit of side effects. No vomiting, no sick tummy, and no diahhrea. Echoing what Suzy said, things tasted like cardboard, and I had to force myself to eat, but since I was a heffalump, I needed to lose a little weight.

Betsydoglover's picture
Betsydoglover
Posts: 1256
Joined: Jul 2005

I did 18 weeks of Xeloda - twice (2 weeks on / 1 week off).  No nausea - GI tract felt a bit irritated from time to time, but again never any nausea.  Tired, but not so that I couldn't work.

 

Take care,

Annabelle41415's picture
Annabelle41415
Posts: 6477
Joined: Feb 2009

That was my first round of treatment along with radiation and didn't have any problem with it at all.  They say use a lot of lotion for your hands and feet.  Hope you don't get sick and can tolerate it well.

Kim

Canadian Sandy's picture
Canadian Sandy
Posts: 607
Joined: Jul 2016

I tolerated xeloda very well. When diarhea started took Imodium and it went away. Was on it for 3 treatments.

PamRav's picture
PamRav
Posts: 274
Joined: Jan 2017

I seem to be one of he few that did not tolerate zeloda well.   
i had really bad hand and foot.  Very red and peeling skin.  My feet were the worst, I curtailed my walking because of the problems. 
I took it in ever decreasing doses but in the end I had to stop.  I started out with 2 wk on and 1 off, I transitioned to every other week. 
no nausea, vomiting or diarhea though.  
hope it works for you, it's easier than the IV form (5fu) which surprise ingly i tolerated well 

kswatson
Posts: 2
Joined: Feb 2020

I currently take 4000 mg a day of Xeloda 14 days on 7 days off then an infusion with Oxplaytin. I am handling it well. The side effects for me have been minimal so far. It was very scarey at first but I am doing well. I hope this helps 

Annabelle41415's picture
Annabelle41415
Posts: 6477
Joined: Feb 2009

It's great that you are doing well on the Xeloda as well.  That oxy is a nasty drug, so be careful if you find that your symptoms are not tolerable or lasting from one infusion to the next. 

Kim

abrub's picture
abrub
Posts: 2130
Joined: Mar 2010

I had that in 2008 - NASTY!  I'm only on the 5FU (xeloda) and Avastin.

Thanks for caring!

Alice

abrub's picture
abrub
Posts: 2130
Joined: Mar 2010

I'm on the 3rd day of 1500/am; 1000/pm with Avastin infusion on day 1.  So far, so good.  I'll be doing 7 days on; 7 off; with Avastin on Day 1 every other week.

I'm working on keeping hands and feet well moisturized, and doing frequent mouth rinses to avoid mouth sores.

Thanks to everyone for your input.

Alice

Annabelle41415's picture
Annabelle41415
Posts: 6477
Joined: Feb 2009

I'm so glad to hear that things are going well so far with the Xeloda, especially since everyone reacts different.  It is very important to make sure that the lotion is applied often, even when you don't think you need it.  Hope you continmue to do well.

Kim

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