HOPE for glioblastoma!

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I_Promise
I_Promise CSN Member Posts: 218 Member
in Brain Cancer #1
Yay for
ICT-107 Phase II Clinical Trial - FDA APPROVED!

The dendritic vaccine is making progress! There is HOPE,

Julia

Comments

  • mighty6
    mighty6 CSN Member Posts: 47
    #2
    criteria for this trial
    Julia and all,

    This trial require patient's HLA-A1 r A2 to be positive, which exclude about 30% the GBM patients. but this is promising regardless. My husband is not qualified. but I hope all of others do. good luck!
  • madisonmuzz
    madisonmuzz Member Posts: 13
    #3
    thank goodness
    I hope this is the answers a lot of us are praying for......
  • I_Promise
    I_Promise CSN Member Posts: 218 Member
    #4
    madisonmuzz said:

    thank goodness
    I hope this is the answers a lot of us are praying for......

    if I were a millionaire
    I would have my own lab and arsenal of scientists. I would want to accelerate the research. I would make sure the cure is tomorrow and not in 20 years because I truly believe it is within our grasp.

    Julia
  • I_Promise
    I_Promise CSN Member Posts: 218 Member
    #5
    madisonmuzz said:

    thank goodness
    I hope this is the answers a lot of us are praying for......

    let's continue to hope
    Movement toward Phase III trials is encouragingly on the horizon. The largest clinical trial investigating the use of DC vaccines to treat patients with brain tumors (DCVax®-Brain) is sponsored by Northwest Biotherapeutics.
  • jeffballew
    jeffballew Member Posts: 9
    #6
    vaccine
    it eliminates those who have already begun other treatments. Has anyone seen the Polio Vaccine treatment. it looks promising as well.
  • mighty6
    mighty6 CSN Member Posts: 47
    #7
    jeffballew said:

    vaccine
    it eliminates those who have already begun other treatments. Has anyone seen the Polio Vaccine treatment. it looks promising as well.

    critiria
    you are right.
    ICT-107 requires the consent before chemo
    Dcvx-brain requires it even before surgery
    TVI-brain -- needs to confirm

    I don't know about Polio Vaccine, can you provide more info.?
    thanks,
    Jane
  • jeffballew
    jeffballew Member Posts: 9
    #8
    mighty6 said:

    critiria
    you are right.
    ICT-107 requires the consent before chemo
    Dcvx-brain requires it even before surgery
    TVI-brain -- needs to confirm

    I don't know about Polio Vaccine, can you provide more info.?
    thanks,
    Jane

    polio vaccine
    The Polio Vaccine is through Duke, where I get my treatment. I am a candidate, and i've had Temodar and Avastin.

    you can google it but here are 2 urls
    http://www.ncbi.nlm.nih.gov/pubmed/18766173

    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881183/

    my oncologist has high hopes once it passes the IRB. The viral technology is thought to stimulate the immune system to attack the tumor. There are actually polio virus receptors on the glioblastoma and the polio virus impregnates the tumor and it leads to a large inflammatory response.
  • I_Promise
    I_Promise CSN Member Posts: 218 Member
    #9
    jeffballew said:

    polio vaccine
    The Polio Vaccine is through Duke, where I get my treatment. I am a candidate, and i've had Temodar and Avastin.

    you can google it but here are 2 urls
    http://www.ncbi.nlm.nih.gov/pubmed/18766173

    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881183/

    my oncologist has high hopes once it passes the IRB. The viral technology is thought to stimulate the immune system to attack the tumor. There are actually polio virus receptors on the glioblastoma and the polio virus impregnates the tumor and it leads to a large inflammatory response.

    thank you for the info
    I will check it out
  • mighty6
    mighty6 CSN Member Posts: 47
    #10
    jeffballew said:

    polio vaccine
    The Polio Vaccine is through Duke, where I get my treatment. I am a candidate, and i've had Temodar and Avastin.

    you can google it but here are 2 urls
    http://www.ncbi.nlm.nih.gov/pubmed/18766173

    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881183/

    my oncologist has high hopes once it passes the IRB. The viral technology is thought to stimulate the immune system to attack the tumor. There are actually polio virus receptors on the glioblastoma and the polio virus impregnates the tumor and it leads to a large inflammatory response.

    did you get in the polio vaccine trial?

    Thanks for the reply. I did no notice it till now.
    Did you get into this trial eventually? Hope things are going good with you. Do you know if that trial requires surgery to be done in Duke? My husband was dx. 3 months ago. he had surgery and 6-weeks radiation in another city.

    thanks again. Jane

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