Question with anti-nausea drugs

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Cinkal
Cinkal Member Posts: 161
I had my first chemo treatment today (A/C). I was given a anti-nausea med through my iv and a steroid(dexamethasone) to take for four days after. They also gave me two different anti nausea drugs to take if I feel nauseas . The nurse said to wait and take if I feel nausea. I have read on this site it is wiser to take them before you feel sick. Any suggestions?
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  • chriskaput
    chriskaput Member Posts: 109
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    I would take it now
    I took a nausea pill the morning of chemo treatment (1 hr before) and 1 pill each day for 2 days after. It was a 3 pill pack. I forget the name of it. I also had the anti-nausea med through my IV. AC made me very nauseas, so my onc. prescribed me another anti-nauseau pill to take if needed. I took that too! If I were you I'd take it before you feel any nausea. Wishing you all the best.

    Chris.
  • Rague
    Rague Member Posts: 3,653 Member
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    Did you have Morning Sickness?
    My first question/comment is - did you have morning sickness? According to what I've been told that has a lot to do with rather or not you have Chemo nausea problems. Can only pseak for myself - I had no Morning sickness with either of my Sons - I had no Chemo nausea even when I stopped taking the anti-nausea meds. With A/C I was given anti meds IV before Infusion I was also given Emend, dex and 2 others - don't remember which right now. I never had any nausea problems. When i started Taxol was again given IV 'stuff' and Dex and something else - no problems at all and I decided to stop taking them about 1/2 way through - never had any nausea.

    Remember we are all so different!

    Susan

    edit added - i was told to take meds to prevent nausea or pain before it got bad if you needed it - better to keep in control than get back under control.
  • CypressCynthia
    CypressCynthia Member Posts: 4,014 Member
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    I have the worst stomach in
    I have the worst stomach in the world--the first to get nauseated under normal circumstances. So, of course, I got hit really hard with nausea and vomiting and was told to take my nausea meds every day I had chemo.

    Everyone is so different though. If you have a strong stomach, you might do ok. But I didn't have A/C so I'll let those ladies answer.
  • Kat11
    Kat11 Member Posts: 1,931 Member
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    I have the worst stomach in
    I have the worst stomach in the world--the first to get nauseated under normal circumstances. So, of course, I got hit really hard with nausea and vomiting and was told to take my nausea meds every day I had chemo.

    Everyone is so different though. If you have a strong stomach, you might do ok. But I didn't have A/C so I'll let those ladies answer.

    The 3 pack pill is called
    The 3 pack pill is called Emend. It is a great antinausea drugs. I was given this for AC as well as sofran and compozian not sure of spelling. I took the meds 1 hr before chemo and then the others every 4 hrs. I never got sick, did pretty good except for being tired and needing to sleep. Hope this helps you.
    kathy
  • BioAdoptMom
    BioAdoptMom Member Posts: 358
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    I haven't started chemo yet
    I haven't started chemo yet so have no personal experience, but my principal's DH is going through it now for colon cancer. One of the first things she shared with me (she knows I have BC and we were just chatting one day) was that he told her if he takes his meds around the clock the first few days after a treatment, before he feels sick, it works much more effectively.

    Good luck with your treatments!

    Nancy
  • Texasgirl10
    Texasgirl10 Member Posts: 668
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    I haven't started chemo yet
    I haven't started chemo yet so have no personal experience, but my principal's DH is going through it now for colon cancer. One of the first things she shared with me (she knows I have BC and we were just chatting one day) was that he told her if he takes his meds around the clock the first few days after a treatment, before he feels sick, it works much more effectively.

    Good luck with your treatments!

    Nancy

    every 4 hours
    I had an anti nausea med in my chemo, but I would also take compazine every 4 hours around the clock for 4 days following chemo. I just took my last one on Sunday :) I also drank TONS of water starting the day before chemo and for about 1 1/2 weeks after chemo to help flush out the toxins.

    Hugs,

    Dawne
  • MAJW
    MAJW Member Posts: 2,510 Member
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    every 4 hours
    I had an anti nausea med in my chemo, but I would also take compazine every 4 hours around the clock for 4 days following chemo. I just took my last one on Sunday :) I also drank TONS of water starting the day before chemo and for about 1 1/2 weeks after chemo to help flush out the toxins.

    Hugs,

    Dawne

    Take 'em!
    I was told to take them every 4-6 hours...started them the day before chemo and continued for 4 days after...reason being, easier to PREVENT nausea and vomiting than to get it under control once it starts...I was asked the same thing Rague talked about...first question Did I have morning sickness..boy did I have morning sickness! Had it the entire time with my first child...then 6 months with the second...I thought I was doomed then with chemo...I was absolutely fanatical about taking the anti nausea meds...and I never had the first wave of nausea...they stressed taking them and I did! They can't hurt you..so my advice is "take 'em!
    Wishing you well...
  • Hippiechick58
    Hippiechick58 Member Posts: 320
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    MAJW said:

    Take 'em!
    I was told to take them every 4-6 hours...started them the day before chemo and continued for 4 days after...reason being, easier to PREVENT nausea and vomiting than to get it under control once it starts...I was asked the same thing Rague talked about...first question Did I have morning sickness..boy did I have morning sickness! Had it the entire time with my first child...then 6 months with the second...I thought I was doomed then with chemo...I was absolutely fanatical about taking the anti nausea meds...and I never had the first wave of nausea...they stressed taking them and I did! They can't hurt you..so my advice is "take 'em!
    Wishing you well...

    I needed the Emend, Zofran
    I needed the Emend, Zofran and Compazine round the clock, but I never once vomited, just felt nauseous. Especially with the A/C, that was the worst. The Taxol didn't produce too much nausea, but gave me excruciating bone pain. My advice to you is to take them before you feel nauseous. I feel they work better that way. Good luck to you.

    Be Well,
    Dianne
  • NJMom10
    NJMom10 Member Posts: 176
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    I needed the Emend, Zofran
    I needed the Emend, Zofran and Compazine round the clock, but I never once vomited, just felt nauseous. Especially with the A/C, that was the worst. The Taxol didn't produce too much nausea, but gave me excruciating bone pain. My advice to you is to take them before you feel nauseous. I feel they work better that way. Good luck to you.

    Be Well,
    Dianne

    Emend and Zofran
    I took Emend in a 3 pill pack, the first 1 hour before treatment and then each morning for 2 days. I also took Zofran, 1 the evening of the treatment and then 3 xs per day for a day or 2 after. My onc nurses said not to take it until I felt nauseous too. But I read that it is easier to prevent nauseau than to stop it when it starts so I just took it on the schedule. I never got sick during any treatments. 4 AC then 4 Taxol. I didn't need any anti nauseau meds during the Taxol.
  • Cinkal
    Cinkal Member Posts: 161
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    I needed the Emend, Zofran
    I needed the Emend, Zofran and Compazine round the clock, but I never once vomited, just felt nauseous. Especially with the A/C, that was the worst. The Taxol didn't produce too much nausea, but gave me excruciating bone pain. My advice to you is to take them before you feel nauseous. I feel they work better that way. Good luck to you.

    Be Well,
    Dianne

    Thanks Ladies for the
    Thanks Ladies for the advice. This sight is so wonderful. I felt a little queasy so decided to take some of the antinauesa last night and one after breakfast. So far, it seems to be working.
  • Boppy_of_6
    Boppy_of_6 Member Posts: 1,138
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    Rague said:

    Did you have Morning Sickness?
    My first question/comment is - did you have morning sickness? According to what I've been told that has a lot to do with rather or not you have Chemo nausea problems. Can only pseak for myself - I had no Morning sickness with either of my Sons - I had no Chemo nausea even when I stopped taking the anti-nausea meds. With A/C I was given anti meds IV before Infusion I was also given Emend, dex and 2 others - don't remember which right now. I never had any nausea problems. When i started Taxol was again given IV 'stuff' and Dex and something else - no problems at all and I decided to stop taking them about 1/2 way through - never had any nausea.

    Remember we are all so different!

    Susan

    edit added - i was told to take meds to prevent nausea or pain before it got bad if you needed it - better to keep in control than get back under control.

    No morning sickness here
    That is really interesting Susan. I did not have morning sickness with either of my 2 pregnancies or with chemo. I did take my compazine for a couple of days after tx even if I was not nauseous, that is what the nurses told me to do. I had the dex with chemo and an antinausea drug in IV too. God Bless
    (((hugs))) Janice
  • joannstar
    joannstar Member Posts: 403 Member
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    I took Emmend
    which worked great while I was on Taxotere/Cytoxan. When I was switched to Taxol/Cytoxan I no longer was given emmend and I felt a bit of nausea but took compazine. I was given a sample of Zophran, but it was 3 years past expiration date so I never took it.
    My onc said that if I had ever smoked cigarettes (been 25 years since I quit) it would also help and I wouldn't get as nauseas.
    All the meds said to take them before feeling any nausea which I did.
    Good luck,
    JoAnn
  • Rague
    Rague Member Posts: 3,653 Member
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    joannstar said:

    I took Emmend
    which worked great while I was on Taxotere/Cytoxan. When I was switched to Taxol/Cytoxan I no longer was given emmend and I felt a bit of nausea but took compazine. I was given a sample of Zophran, but it was 3 years past expiration date so I never took it.
    My onc said that if I had ever smoked cigarettes (been 25 years since I quit) it would also help and I wouldn't get as nauseas.
    All the meds said to take them before feeling any nausea which I did.
    Good luck,
    JoAnn

    I've never heard that being
    I've never heard that being a smoker (or ex-smoker) would help with nausea. Definately had nothing to do me not having nausea as I've never smoked at all. Well - that's not 100% true anymore - I did take a 'puff' of tobacco from the peace pipe at the last Sweat Lodge but that was almost a year after last Chemo.

    Susan
  • creampuff91344
    creampuff91344 Member Posts: 988
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    joannstar said:

    I took Emmend
    which worked great while I was on Taxotere/Cytoxan. When I was switched to Taxol/Cytoxan I no longer was given emmend and I felt a bit of nausea but took compazine. I was given a sample of Zophran, but it was 3 years past expiration date so I never took it.
    My onc said that if I had ever smoked cigarettes (been 25 years since I quit) it would also help and I wouldn't get as nauseas.
    All the meds said to take them before feeling any nausea which I did.
    Good luck,
    JoAnn

    Word of Caution
    As the prior posts have stated, all of us are different. Unfortunately, I had problems with nausea all during chemo. I took Emmend the day before and for the next four days following chemo. Also, IV drip just before treatment. I still had lingering nausea for the full six treatments, so we tried all kinds of nausea meds. Finally was prescribed Reglan (generic drug is Metoclopram), which stopped the nausea immediately. I took it four times a day for approximately 3 months. About three months after stopping this drug, I started to develope neurological problems (involuntary tongue and extremity movement), and extreme anxiety. The Reglan is linked to a disease called Tardive Dyskinesia, and is non-cureable. All they can do is treat the symptoms. Just a word of caution...research any meds you are prescribed. Reglan had a "Black Label" placed on it in February 2009, just after I stopped taking the drug. Three years later I still am having to medicate to prevent the seizures and anxiety. Just be careful with what you take. By the way, Reglan is also used to treat schizophrenia, and some patients take it for 20/30 years. The results are the horrible facial movements and twitches that are distinct to these patients. They now feel that the drug taken over an extended period of time is what causes them to be so dibilitated. I only took for a short period, and will probably have these minor symptoms for the rest of my life. Just be cautious. Hugs, Judy
  • Rague
    Rague Member Posts: 3,653 Member
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    Word of Caution
    As the prior posts have stated, all of us are different. Unfortunately, I had problems with nausea all during chemo. I took Emmend the day before and for the next four days following chemo. Also, IV drip just before treatment. I still had lingering nausea for the full six treatments, so we tried all kinds of nausea meds. Finally was prescribed Reglan (generic drug is Metoclopram), which stopped the nausea immediately. I took it four times a day for approximately 3 months. About three months after stopping this drug, I started to develope neurological problems (involuntary tongue and extremity movement), and extreme anxiety. The Reglan is linked to a disease called Tardive Dyskinesia, and is non-cureable. All they can do is treat the symptoms. Just a word of caution...research any meds you are prescribed. Reglan had a "Black Label" placed on it in February 2009, just after I stopped taking the drug. Three years later I still am having to medicate to prevent the seizures and anxiety. Just be careful with what you take. By the way, Reglan is also used to treat schizophrenia, and some patients take it for 20/30 years. The results are the horrible facial movements and twitches that are distinct to these patients. They now feel that the drug taken over an extended period of time is what causes them to be so dibilitated. I only took for a short period, and will probably have these minor symptoms for the rest of my life. Just be cautious. Hugs, Judy

    Good point - Reglan Bad
    I remembered that someone had warned me about Reglan when I started Chemo in Aug '09 - but didn't remember who - now I do and Thank You. I had been given Reglan to take IF I needed extra anti-nausea 'stuff'. I never needed any but I got a different script for something else 'just in case' - don't remember want it was now.

    Susan
  • creampuff91344
    creampuff91344 Member Posts: 988
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    Rague said:

    Good point - Reglan Bad
    I remembered that someone had warned me about Reglan when I started Chemo in Aug '09 - but didn't remember who - now I do and Thank You. I had been given Reglan to take IF I needed extra anti-nausea 'stuff'. I never needed any but I got a different script for something else 'just in case' - don't remember want it was now.

    Susan

    You're Welcome
    Susan, any time I see someone post about having trouble with nausea, and trying different drugs, I give them the same warning. Believe me when I say, I wish someone had warned me about the effects of Reglan before I took it. Maybe this will help someone else avoid this awful disease. Hugs, Judy
  • CypressCynthia
    CypressCynthia Member Posts: 4,014 Member
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    Rague said:

    Good point - Reglan Bad
    I remembered that someone had warned me about Reglan when I started Chemo in Aug '09 - but didn't remember who - now I do and Thank You. I had been given Reglan to take IF I needed extra anti-nausea 'stuff'. I never needed any but I got a different script for something else 'just in case' - don't remember want it was now.

    Susan

    According to my chemo nurse, reglan is still sometimes used, but, of course, the risks are made clear to the patient. With certain types of chemo it is sometimes still one of the only effective anti-nausea meds. Risk greatly increases if the drug is used chronically--greater than 12 weeks.

    Reglan should be avoided because no one wants permanent TD. However, there may be isolated cases where it is still an important drug. Reglan was very helpful for me years ago and one of the only drugs that I could take. I took it 2 weeks on with cogentin; then 2 weeks off and I did this regimen for 6 months. I went from being totally incapacitated with nausea and vomiting to just a little queasy. I was then able to work throughout chemo.

    Of course, that was 1987. Today I would first try whatever else that I could, but my personal options are limited. If I had to take it, with my history of severe nausea and vomiting, I would, but would take it for as short a course as possible and then switch to something less effective.

    My point is that we are all different and our situations are different. Be aware of the risks and talk with your health care providers.
  • creampuff91344
    creampuff91344 Member Posts: 988
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    According to my chemo nurse, reglan is still sometimes used, but, of course, the risks are made clear to the patient. With certain types of chemo it is sometimes still one of the only effective anti-nausea meds. Risk greatly increases if the drug is used chronically--greater than 12 weeks.

    Reglan should be avoided because no one wants permanent TD. However, there may be isolated cases where it is still an important drug. Reglan was very helpful for me years ago and one of the only drugs that I could take. I took it 2 weeks on with cogentin; then 2 weeks off and I did this regimen for 6 months. I went from being totally incapacitated with nausea and vomiting to just a little queasy. I was then able to work throughout chemo.

    Of course, that was 1987. Today I would first try whatever else that I could, but my personal options are limited. If I had to take it, with my history of severe nausea and vomiting, I would, but would take it for as short a course as possible and then switch to something less effective.

    My point is that we are all different and our situations are different. Be aware of the risks and talk with your health care providers.

    You are right
    Cynthia, you are right when you say everyone is different. The Black Label Warning for Reglan by the FDA specifically states that "elderly females" are more at risk for developing TD than anyone. As I fall into that category (I was 63 when I took Reglan), I would have thought the onc would have warned me about the possibility of TD, and let me make up my mind if I was willing to accept the risk. The drug did do the trick as far as eliminating my nausea, but certainly was not worth the current condition that it produced in my body. I was prescribed four tablets a day for 3 months, and took it religiously as otherwise I was incapacitated with nausea. It definitely did work for me as far as nausea is concerned, but not worth the heartache it has caused. I would rather warn someone about the possibilities of the drug and let them decide their own situation. Judy
  • Rague
    Rague Member Posts: 3,653 Member
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    You are right
    Cynthia, you are right when you say everyone is different. The Black Label Warning for Reglan by the FDA specifically states that "elderly females" are more at risk for developing TD than anyone. As I fall into that category (I was 63 when I took Reglan), I would have thought the onc would have warned me about the possibility of TD, and let me make up my mind if I was willing to accept the risk. The drug did do the trick as far as eliminating my nausea, but certainly was not worth the current condition that it produced in my body. I was prescribed four tablets a day for 3 months, and took it religiously as otherwise I was incapacitated with nausea. It definitely did work for me as far as nausea is concerned, but not worth the heartache it has caused. I would rather warn someone about the possibilities of the drug and let them decide their own situation. Judy

    I too was an "Elderly female"
    (63 when prescribed it) and nothing was said to me about the possiblities of permanent SE's had I taken it. Actually I never would have taken it even IF I hadn't been advised about it here as I had no nausea during either A/C or Taxol. I find it hard to believe that there is no other med that will work either alone or perhaps in conjuction without the permanent SE's.

    Susan
  • camul
    camul Member Posts: 2,537
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    Never had morning sickness, but do get nauseated
    With the first round of chemo in 2002, I was sick for 3 days regardless of what they gave me. The only thing that stopped it was illegal, and it took til the last treatment b4 I did that and found that one or two puffs cured it! lol

    With Abraxane I am nauseated for about 3-5 days, but do not get the relief that I did when I actually got sick. I am just hazy and feel like I have the flu. So I have come to the conclusion that each combo of meds is different as is each infusion. One time I might feel really nauseated and with the next one, not so much or for as long. But so far, with this last 9 rounds, didn't have to resort to the 1 -2 puffs :))

    Now, I will see what the next 9 will do!