Cancer cells killed by chemotherapy may cause cancer to spread..

mono5
mono5 Member Posts: 94
edited March 2014 in Breast Cancer #1
Chemotherapy is known to come with a long list of side effects -- from debilitating nausea and hair loss to extreme fatigue -- and in many cases, it does not cure or even stop cancer from progressing. But what if chemotherapy does something no one has realized before during all the decades it has been in use? What if chemo actually encourages cancer to spread throughout the body, the process known as metastasis?
Click on link below...
http://main.uab.edu/Sites/MediaRelations/articles/77885/
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Comments

  • jo jo
    jo jo Member Posts: 1,175
    That is some scary stuff...i
    That is some scary stuff...i dont know what to say about that...im speachless!
    Thanks for sharing this.
  • bluwillo
    bluwillo Member Posts: 113
    jo jo said:

    That is some scary stuff...i
    That is some scary stuff...i dont know what to say about that...im speachless!
    Thanks for sharing this.

    The Rest of the Story...
    From the article at the link....no one knows, so "they" are doing a study. Not quite as awful and scary as it sounds. I'm chillin' on this one!


    Are Dead Cancer Cells Feeding Cancer’s Spread? UAB Awarded $805,000 Grant to Study the Issue
    June 10, 2010

    BIRMINGHAM, Ala. - Researchers with the University of Alabama at Birmingham (UAB) Comprehensive Cancer Center and UAB Department of Chemistry have won an $805,000 grant from the U.S. Department of Defense Breast Cancer Research Program to study whether dead cancer cells left over after treatment encourage cancer's spread to other parts of the body.

    The research centers on examining inactivated or altered genetic material (DNA) left in the body after breast-cancer cells are exposed to chemotherapy. UAB researchers say the resulting altered DNA may be the factor that activates the spread of living cancer cells to distant locations in the body - a deadly process called metastasis - through a specific molecular pathway.
  • Skeezie
    Skeezie Member Posts: 586 Member
    bluwillo said:

    The Rest of the Story...
    From the article at the link....no one knows, so "they" are doing a study. Not quite as awful and scary as it sounds. I'm chillin' on this one!


    Are Dead Cancer Cells Feeding Cancer’s Spread? UAB Awarded $805,000 Grant to Study the Issue
    June 10, 2010

    BIRMINGHAM, Ala. - Researchers with the University of Alabama at Birmingham (UAB) Comprehensive Cancer Center and UAB Department of Chemistry have won an $805,000 grant from the U.S. Department of Defense Breast Cancer Research Program to study whether dead cancer cells left over after treatment encourage cancer's spread to other parts of the body.

    The research centers on examining inactivated or altered genetic material (DNA) left in the body after breast-cancer cells are exposed to chemotherapy. UAB researchers say the resulting altered DNA may be the factor that activates the spread of living cancer cells to distant locations in the body - a deadly process called metastasis - through a specific molecular pathway.

    And it's just a theory. The grant is only for $850,000 which
    isn't very much. In the 70's there was no chemo and people died, in the 80's there was no Neulasta and people's WBC dropped, they couldn't continue chemo and they died (my mother) and now we are saving lives because of these miracle drugs. The research continues to find a cure, and/or a better treatment. Breast cancer used to be a death sentence (as were all cancers) but many are treated and survivors are living long healthy lives.

    Hopefully someday there will be a cure or certainly a better, easier treatment...but in the meantime we have chemo and rads. It's not perfect but it's all we have. Not to take chemo because of one theory would be foolish, I'll take my chances with what there is available at this time. It's far from perfect, but it's all we have.

    We are just always being bombarded with scary stuff huh? I wonder why it hasn't been reported by the media...or am I missing something?

    Hugs, Judy :-)
  • camsgram
    camsgram Member Posts: 106
    I find it very strange that
    I find it very strange that I have never seen a post from you and then you just blurt this out with no explaination of why we needed to see this. Thanks so much for something else to worry about. 850.000 is not much money for a reliable study
  • carkris
    carkris Member Posts: 4,553 Member
    camsgram said:

    I find it very strange that
    I find it very strange that I have never seen a post from you and then you just blurt this out with no explaination of why we needed to see this. Thanks so much for something else to worry about. 850.000 is not much money for a reliable study

    agree with skeezie and
    agree with skeezie and camsgram
  • VickiSam
    VickiSam Member Posts: 9,079 Member
    carkris said:

    agree with skeezie and
    agree with skeezie and camsgram

    Incomplete data out there .. where are the
    government watchdog's ? Let's scare the crap out of everyone!



    VickiSam
  • Rague
    Rague Member Posts: 3,653 Member
    Skeezie said:

    And it's just a theory. The grant is only for $850,000 which
    isn't very much. In the 70's there was no chemo and people died, in the 80's there was no Neulasta and people's WBC dropped, they couldn't continue chemo and they died (my mother) and now we are saving lives because of these miracle drugs. The research continues to find a cure, and/or a better treatment. Breast cancer used to be a death sentence (as were all cancers) but many are treated and survivors are living long healthy lives.

    Hopefully someday there will be a cure or certainly a better, easier treatment...but in the meantime we have chemo and rads. It's not perfect but it's all we have. Not to take chemo because of one theory would be foolish, I'll take my chances with what there is available at this time. It's far from perfect, but it's all we have.

    We are just always being bombarded with scary stuff huh? I wonder why it hasn't been reported by the media...or am I missing something?

    Hugs, Judy :-)

    It's like this (as far as
    It's like this (as far as I'm concerned) - IF I hadn't had chemo, there is no way I would be alive today. IF/WHEN I get mets - I will deal with those issues at that time - but I Thank my Heavenly Father for the knowledge/treatments that are available TODAY so that I live each day I have given! At this time, it is the best option so, I did all I could to fight. My particualr cancer, Inflammatory BC, is notorious for spreading, with not a very good long term survival rate. IF/WHEN it raises it's ugly head somewhere else - I'll fight it as hard as possible but at least I'll be here to fight!!

    One thing that 'hit' me in the article - it doesn't mention anything about that there are different types/causes of BC and they react differently and spread differently. All cancer is not 'created equal', nor does it respond equally.

    Susan
  • SIROD
    SIROD Member Posts: 2,194 Member
    Chemotherapy is a
    Chemotherapy is a combination of drugs that kill all fast growing cells. Some cells will escape. They are to small to see, (even with the best technology) they will lie dormant for months or years, wake up and cause havoc again. Some are more aggressive, learn how to deactivate chemicals and return quickly. The aggressive ones return sooner, other's can return 37 years later. Breast cancer has no end date for recurrence. Five, ten, fifteen, twenty and even thirty to forty years later, you can have a recurrence of your original breast cancer. I have known women in each of those years.

    The best thing is to enjoy each day, it is all that every living thing on this planet has.

    SIROD
  • chenheart
    chenheart Member Posts: 5,159
    VickiSam said:

    Incomplete data out there .. where are the
    government watchdog's ? Let's scare the crap out of everyone!



    VickiSam

    Ouch! My tongue is in my cheek! For the most part, anyway...
    YEAH! Let's tell our Drs we are on to them~ I don't know why my oncologist would give his own mother and daughter the same chemo cocktail I am getting...what a fiend! And the scientists rejoicing in the laboratories when cancer cells are killed off, never to replicate~ what's up with those white coats? Dastardly!

    I say, we all go naked, hang from chandeliers, have enemas made from the not quite ripe pods of berries found in the poop of prehistoric orangutans admisinistered to us by blind pygmies, and hope for the best!

    I know everything isn't perfect. I know not everyone is altruistic. I know some are driven by greed. And as of today, there is no Cure. But I am still thankful to be able to get traditional treatment today, coupled with supplements and food and exercise to hopefully boost my immune system. And as with Polio, (and I AM old enough to remember kids in leg braces and iron-lungs) pharmaceuticals absolutely did eradicate that disease! Almost every child going to school in the USA in the 1950's had Jonas Salk's sugar cube of anti-polio drugs given to him. And when was the last time you knew of anyone with Polio? Do your children even know what it is? To paraphrase MLK, "I have a dream" that cancer will one day go the way of Polio.

    Hopeful Hugs,
    Chen&hearts:
  • SIROD
    SIROD Member Posts: 2,194 Member
    chenheart said:

    Ouch! My tongue is in my cheek! For the most part, anyway...
    YEAH! Let's tell our Drs we are on to them~ I don't know why my oncologist would give his own mother and daughter the same chemo cocktail I am getting...what a fiend! And the scientists rejoicing in the laboratories when cancer cells are killed off, never to replicate~ what's up with those white coats? Dastardly!

    I say, we all go naked, hang from chandeliers, have enemas made from the not quite ripe pods of berries found in the poop of prehistoric orangutans admisinistered to us by blind pygmies, and hope for the best!

    I know everything isn't perfect. I know not everyone is altruistic. I know some are driven by greed. And as of today, there is no Cure. But I am still thankful to be able to get traditional treatment today, coupled with supplements and food and exercise to hopefully boost my immune system. And as with Polio, (and I AM old enough to remember kids in leg braces and iron-lungs) pharmaceuticals absolutely did eradicate that disease! Almost every child going to school in the USA in the 1950's had Jonas Salk's sugar cube of anti-polio drugs given to him. And when was the last time you knew of anyone with Polio? Do your children even know what it is? To paraphrase MLK, "I have a dream" that cancer will one day go the way of Polio.

    Hopeful Hugs,
    Chen&hearts:

    Polio and Cancer
    To compare cancer with polio is comparing apples and oranges. They may be fruit, but they are not the same.

    One needs to really study what is Breast Cancer and how many variations there are. It's not one disease but many under one umbrella. There won't ever be one cure with one size fits all. They have a handle on 3 types, ER, PR and HER2 positives. With those attributes in your tumor, there are many more options. When a woman or man is triple negative, the harsher treatments are their only reality. However, the triple positives, after they have used all the target drugs, end up no different than their triple negatives. In the end, those malignant cells are still the victors.

    I do believe that some day, cancer might go the way of Polio, but it won't be in my life time. When Nixon declared the "War on Cancer", science and medicine had not idea what it really was all about. Read, "One Renegade Cell", a good explanation on how we are doing.

    SIROD
  • Rague
    Rague Member Posts: 3,653 Member
    chenheart said:

    Ouch! My tongue is in my cheek! For the most part, anyway...
    YEAH! Let's tell our Drs we are on to them~ I don't know why my oncologist would give his own mother and daughter the same chemo cocktail I am getting...what a fiend! And the scientists rejoicing in the laboratories when cancer cells are killed off, never to replicate~ what's up with those white coats? Dastardly!

    I say, we all go naked, hang from chandeliers, have enemas made from the not quite ripe pods of berries found in the poop of prehistoric orangutans admisinistered to us by blind pygmies, and hope for the best!

    I know everything isn't perfect. I know not everyone is altruistic. I know some are driven by greed. And as of today, there is no Cure. But I am still thankful to be able to get traditional treatment today, coupled with supplements and food and exercise to hopefully boost my immune system. And as with Polio, (and I AM old enough to remember kids in leg braces and iron-lungs) pharmaceuticals absolutely did eradicate that disease! Almost every child going to school in the USA in the 1950's had Jonas Salk's sugar cube of anti-polio drugs given to him. And when was the last time you knew of anyone with Polio? Do your children even know what it is? To paraphrase MLK, "I have a dream" that cancer will one day go the way of Polio.

    Hopeful Hugs,
    Chen&hearts:

    Salk was a shot
    Salk vaccine (1955) was a shot. Sabin oral vaccine (1958) was the sugar cube that came later.
  • chenheart
    chenheart Member Posts: 5,159
    SIROD said:

    Polio and Cancer
    To compare cancer with polio is comparing apples and oranges. They may be fruit, but they are not the same.

    One needs to really study what is Breast Cancer and how many variations there are. It's not one disease but many under one umbrella. There won't ever be one cure with one size fits all. They have a handle on 3 types, ER, PR and HER2 positives. With those attributes in your tumor, there are many more options. When a woman or man is triple negative, the harsher treatments are their only reality. However, the triple positives, after they have used all the target drugs, end up no different than their triple negatives. In the end, those malignant cells are still the victors.

    I do believe that some day, cancer might go the way of Polio, but it won't be in my life time. When Nixon declared the "War on Cancer", science and medicine had not idea what it really was all about. Read, "One Renegade Cell", a good explanation on how we are doing.

    SIROD

    I think you misunderstood my
    I think you misunderstood my point...the comparison was only that science, research and eventually drugs, spelled the demise of Polio~ not that the diseases are alike in any way! I have no argument with you as to the nature of the Beast, and the war that is still being waged. Simply that in my opinion, (and it doesn't need to be anyone elses of course!) that it isn't a "them vs us"! Perhaps no one ever thought that Polio would be eradicated in their lifetimes either, and yet, in SOMEONE'S lifetime, it was!

    Without hope, I am nothing...so I hope that one day, Cancer will also be in the history books, with old-fashioned pictures of people being hooked up to IVs and chldren not recognizing what in the world that is. I always say I am Not a Pollyanna, but I admit, on this front, I am! And I am too old to change! LOL

    Hopeful Hugs,
    Chen
  • chenheart
    chenheart Member Posts: 5,159
    Rague said:

    Salk was a shot
    Salk vaccine (1955) was a shot. Sabin oral vaccine (1958) was the sugar cube that came later.

    I recall...I was in 1st
    I recall...I was in 1st grade in 55...so I do remember both! I wonder how scared/excited our parents were???
  • SIROD
    SIROD Member Posts: 2,194 Member
    chenheart said:

    I think you misunderstood my
    I think you misunderstood my point...the comparison was only that science, research and eventually drugs, spelled the demise of Polio~ not that the diseases are alike in any way! I have no argument with you as to the nature of the Beast, and the war that is still being waged. Simply that in my opinion, (and it doesn't need to be anyone elses of course!) that it isn't a "them vs us"! Perhaps no one ever thought that Polio would be eradicated in their lifetimes either, and yet, in SOMEONE'S lifetime, it was!

    Without hope, I am nothing...so I hope that one day, Cancer will also be in the history books, with old-fashioned pictures of people being hooked up to IVs and chldren not recognizing what in the world that is. I always say I am Not a Pollyanna, but I admit, on this front, I am! And I am too old to change! LOL

    Hopeful Hugs,
    Chen

    I remember the polio scare
    I remember the polio scare too. Old enough to have been there. Dr. Salk used the HeLa cells that made it possible to have the vaccine. HeLa cells don't die and are used today in research. Henrietta Lacks had cervical cancer and cells were taken from her tumor. They were the 1st to continue to live and not die. Her story is in a new book, a good read.

    I think my aunt had barbaric treatments for bc in 1959, Halsted mastectomy and cobalt treatments that burned her. Think we have made great stride and the PARP inhibitors that I forgot to mention are hopeful for our triple negatives.

    In the 1950's I trick or treated for the Jimmy Fund to wipe out childhood leukemia. I told a young man were I work that he is the living proof that my given up candy for money paid off.
    Different ways of researching back then, did lead to a cure. I'm certain it's not all forms of childhood leukemia, but the kind my young friend had, was.

    SIROD
  • chenheart
    chenheart Member Posts: 5,159
    SIROD said:

    I remember the polio scare
    I remember the polio scare too. Old enough to have been there. Dr. Salk used the HeLa cells that made it possible to have the vaccine. HeLa cells don't die and are used today in research. Henrietta Lacks had cervical cancer and cells were taken from her tumor. They were the 1st to continue to live and not die. Her story is in a new book, a good read.

    I think my aunt had barbaric treatments for bc in 1959, Halsted mastectomy and cobalt treatments that burned her. Think we have made great stride and the PARP inhibitors that I forgot to mention are hopeful for our triple negatives.

    In the 1950's I trick or treated for the Jimmy Fund to wipe out childhood leukemia. I told a young man were I work that he is the living proof that my given up candy for money paid off.
    Different ways of researching back then, did lead to a cure. I'm certain it's not all forms of childhood leukemia, but the kind my young friend had, was.

    SIROD

    I am fascinated by the HeLa
    I am fascinated by the HeLa story...I recently saw a feature about her family and how they were completely unaware that her cells were used and are still viable! Amazing!

    Pollyanna Hopeful Hugs,
    Chen♥
  • MyTurnNow
    MyTurnNow Member Posts: 2,686 Member
    SIROD said:

    I remember the polio scare
    I remember the polio scare too. Old enough to have been there. Dr. Salk used the HeLa cells that made it possible to have the vaccine. HeLa cells don't die and are used today in research. Henrietta Lacks had cervical cancer and cells were taken from her tumor. They were the 1st to continue to live and not die. Her story is in a new book, a good read.

    I think my aunt had barbaric treatments for bc in 1959, Halsted mastectomy and cobalt treatments that burned her. Think we have made great stride and the PARP inhibitors that I forgot to mention are hopeful for our triple negatives.

    In the 1950's I trick or treated for the Jimmy Fund to wipe out childhood leukemia. I told a young man were I work that he is the living proof that my given up candy for money paid off.
    Different ways of researching back then, did lead to a cure. I'm certain it's not all forms of childhood leukemia, but the kind my young friend had, was.

    SIROD

    SIROD
    I am an avid reader...what is the name of the book? Thanks.
  • Marcia527
    Marcia527 Member Posts: 2,729
    I read a book about John
    I read a book about John Adams and his daughter had breast cancer. I'm not going to tell you what women went through for treatment in 1811. Breast cancer was greatly feared by women. If you want to read about it google John Adams daughter breast cancer. Warning it's graphic. I'm thankful for present day treatment.
  • Balentine
    Balentine Member Posts: 393
    Marcia527 said:

    I read a book about John
    I read a book about John Adams and his daughter had breast cancer. I'm not going to tell you what women went through for treatment in 1811. Breast cancer was greatly feared by women. If you want to read about it google John Adams daughter breast cancer. Warning it's graphic. I'm thankful for present day treatment.

    Definitely scary stuff
    but I do have to agree that we all know chemo is not perfect but it is all we have right now and there is no doubt that it is saving lives...cannot agrue with that. We do what we can and that is all we can do. That is also why I believe it is so very important that our treatments are followed up by dieticians who specialize in cancer....foods to eat and what foods to avoid for cancer patients because of the fact that chemo is not perfect....I really believe diet plays a major role in cancer cure or cancer recurrence and I have in the past 2-3 weeks began working my way toward becoming a vegetarian. I do eat chicken a few times a weekly but very sparingly. I don't think I can go without some meat in my diet a few times a week but I make sure it is chicken that does not have the added hormones and steroids in it. I have taken sugar out of my diet almost altogether, drink almond milk instead of cows milk, no cheese or eggs, only green tea with no sugar, vitamin D3, aspargus, brocolli, etc. I have lost about 8 pounds in the past 2 weeks and feel great. I am also walking 20-30 minutes a day. We have to do what we can and leave the rest up to God...he will carry us through this and He will give you hope and strength. Love and hugs,
    Lorrie
  • SIROD
    SIROD Member Posts: 2,194 Member
    MyTurnNow said:

    SIROD
    I am an avid reader...what is the name of the book? Thanks.

    HeLa Cells
    The Immortal Life of Henrietta Lacks by Rebecca Skoot. A great, informative read.

    Best,

    SIROD
  • SIROD
    SIROD Member Posts: 2,194 Member
    Rague said:

    Salk was a shot
    Salk vaccine (1955) was a shot. Sabin oral vaccine (1958) was the sugar cube that came later.

    Improvement
    I remember both and thought it was a great improvement in science when it went oral.

    Best to you,

    SIROD