Anyone been on PARP INhibitors? Any feedback? They are offering my mother the opportunity to join a

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Lisa13Q
Lisa13Q Member Posts: 677
edited March 2014 in Ovarian Cancer #1
Anyone know how effective these are? Side effects? I have looked at the research...it looks promising...

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  • nancy591
    nancy591 Member Posts: 1,027 Member
    #2
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    PARP
    There are two clinical trials going on at MSKCC with PARP inhib but I was told the carbo/gem one was full with a waiting list. Dr. S, at MSKCC, told me it really is aimed towards BRCA postive women. Who is your onc? Is Mom brca positive?
  • Lisa13Q
    Lisa13Q Member Posts: 677
    #3
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    nancy591 said:

    PARP
    There are two clinical trials going on at MSKCC with PARP inhib but I was told the carbo/gem one was full with a waiting list. Dr. S, at MSKCC, told me it really is aimed towards BRCA postive women. Who is your onc? Is Mom brca positive?

    Hi Nancy
    There is a new one opening up thats a PARP inhibitor with ABT 888..which is better because the ABT-888 enhances the action of the TMZ...Do you have an e-mail/phone that we can discuss off-line?
  • LPack
    LPack Member Posts: 645
    #4
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    PARP
    Lisa,

    I have that information. When we went for my 2nd opinion, I was offered to join that study if I qualified.

    The sponsor is Abbott Laboratories. You must be in recurrence, never have been on Doxil, BRACA positive and either CA125 above normal or CT scan showing disease.

    I have the consent form in hand, I can give you the information by email or phone. Don't want to take up lots of space here or bore anyone! ☺

    Living for Eternity,
    Libby
  • nancy591
    nancy591 Member Posts: 1,027 Member
    #5
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    Lisa13Q said:

    Hi Nancy
    There is a new one opening up thats a PARP inhibitor with ABT 888..which is better because the ABT-888 enhances the action of the TMZ...Do you have an e-mail/phone that we can discuss off-line?

    offline
    I believe my email is in my CSN info. I put the kids to bed from 8 till 9pm. So after 9pm is best for me if you wish to talk on the phone. Send me an email and I can give you my number.
  • BonnieR
    BonnieR Member Posts: 1,526 Member
    #6
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    parp
    Hi Lisa, I put in to be a parp inhibitor at Mayo last year. I have heard good results from it, but unfortunately there was a very long list so never got called. Pray this is the answer for your mom to give her a break. Hugs ♥ Prayers Bonnie

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