Hormone Therapy aka ADT

mrspjd
mrspjd Member Posts: 694 Member
edited March 2014 in Prostate Cancer #1
HORMONE THERAPY aka ADT (Androgen Deprivation Therapy) or TIP (Testosterone Inactivating Pharmaceuticals)

Below is a link to an excellent article from PCRI Insights Newsletter (Nov. 2010) on ADT aka TIP written by Dr. Mark Scholz, a nationally known and well-respected oncologist specializing in PCa. Dr. Scholz is associated with PCRI. Some may be familar with his recent book on PCa. While the article does leave some questions unanswered, as well as some definitions of terms lacking, nonetheless, this is a very good primer on hormone therapy for anyone interested in learning more about this subject, how testosterone affects PCa and, how it may be a viable & successful tx for intermediate/high risk PCa. BTW, PCRI’s (Prostate Cancer Research Institute) home website (http://www.prostate-cancer.org/pcricms/) is an excellent resource for learning about the many aspects of PCa and also has a very thorough PCa glossary.

Testosterone Inactivating Pharmaceuticals article (including several diagrams and charts):
http://www.prostate-cancer.org/pcricms/node/440

Comments

  • califvader
    califvader Member Posts: 108
    #2
    pondering hormonal therapy
    excellent article. thank you. it helped.
  • califvader
    califvader Member Posts: 108
    #3
    pondering hormonal therapy
    excellent article. thank you. it helped.
  • califvader
    califvader Member Posts: 108
    #4
    pondering hormonal therapy
    excellent article. thank you. it helped.
  • califvader
    califvader Member Posts: 108
    #5
    pondering hormonal therapy
    excellent article. thank you. it helped.
  • FreddyJoe
    FreddyJoe Member Posts: 45 Member
    #6
    Hormone Therapy.
    Very interesting article. I have been wondering why the cancer happens to older men and we must inactivate the production of testosterone,when we are in our declining years of it. In the early ages when the hormones are raging, in both men and women, prostate and breast cancer seem to be rare.
  • mrspjd
    mrspjd Member Posts: 694 Member
    #7
    FreddyJoe said:

    Hormone Therapy.
    Very interesting article. I have been wondering why the cancer happens to older men and we must inactivate the production of testosterone,when we are in our declining years of it. In the early ages when the hormones are raging, in both men and women, prostate and breast cancer seem to be rare.

    IMHO
    While I don't have the stats, I don't believe that breast cancer is rare in younger women, such as in the 20-40 year age group. I believe that, in the future, PCa researchers will find that PCa is not an "old man's" disease, as it is now considered.

    Unless a family history of PCa exists, the fact is that we currently do not regularly test younger men (20-40 yrs) for PSA & PCa because of the argument (which I don't buy if men are properly educated about PCa & tx) that testing then would increase the potential for over treatment. But that could change in the future, and researchers may find, as they did with Multiple Sclerosis, that PCa is not an older person’s disease after all.

    Something to think about.
  • FreddyJoe
    FreddyJoe Member Posts: 45 Member
    #8
    mrspjd said:

    IMHO
    While I don't have the stats, I don't believe that breast cancer is rare in younger women, such as in the 20-40 year age group. I believe that, in the future, PCa researchers will find that PCa is not an "old man's" disease, as it is now considered.

    Unless a family history of PCa exists, the fact is that we currently do not regularly test younger men (20-40 yrs) for PSA & PCa because of the argument (which I don't buy if men are properly educated about PCa & tx) that testing then would increase the potential for over treatment. But that could change in the future, and researchers may find, as they did with Multiple Sclerosis, that PCa is not an older person’s disease after all.

    Something to think about.

    IMHO
    I read a story today about a 4 year old girl who was found to have breast cancer at 2 1/2, very rare, but it can happen. I guess I just do not hear much of younger people having breast or prostate cancer. Maybe because we do not screen younger people.
  • mrspjd
    mrspjd Member Posts: 694 Member
    #9
    FreddyJoe said:

    Hormone Therapy.
    Very interesting article. I have been wondering why the cancer happens to older men and we must inactivate the production of testosterone,when we are in our declining years of it. In the early ages when the hormones are raging, in both men and women, prostate and breast cancer seem to be rare.

    early screening
    Both prostate and breast cancers are hormone sensitive cancers. Screening guidelines/protocols for breast cancer in women usually begin much earlier (in their 20's) than they do for prostate cancer screening in men. Without a family history of PCa, current PCa screening guidelines recommend that testing start at age 50. IMHO, and I believe the opinion of many others whose lives have been affected by PCa, the current PCa screening guidelines need to be changed to start screening at a much earlier age for men.
  • mrspjd
    mrspjd Member Posts: 694 Member
    #10
    mrspjd said:

    IMHO
    While I don't have the stats, I don't believe that breast cancer is rare in younger women, such as in the 20-40 year age group. I believe that, in the future, PCa researchers will find that PCa is not an "old man's" disease, as it is now considered.

    Unless a family history of PCa exists, the fact is that we currently do not regularly test younger men (20-40 yrs) for PSA & PCa because of the argument (which I don't buy if men are properly educated about PCa & tx) that testing then would increase the potential for over treatment. But that could change in the future, and researchers may find, as they did with Multiple Sclerosis, that PCa is not an older person’s disease after all.

    Something to think about.

    oops...
    duplicate post deleted

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