Taxotere and Cytoxan sde effects
Comments
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been thinking of you Millycelinelvr said:update:
Hello sisters. I have been though only half of my chemo but I feel as though I have been on it longer. I have been very emotional. I don't know if it is because of the chemo or all the things I have to deal with right now,(My Mom's death, hair loss, general UUGGHH!) My husband is happily ignorant of my emotional/chemo spells. I think he doesn't know what to do so he lets me cry it out myself. Sometimes I just go bed and "take a nap" to get it out so he doesn't see me.
In addition to all my above side effects I now have leg cramps this time as well. I ended up with sinus, a sore throat, hoarseness, and what felt like bronchitis. I have a really hard cough that hurts my chest and throat. My wbc was up (?) anyway, Onc gave me a strong antibiotic 5 days ago. I think it is all going away. Just in time for my next chemo 4/7.
Milly
You have had so much to deal with..your moms death and all the emotions that come with this plus the emotions of losing your hair. I have been keeping you in my prayers. There will be a time when things start to get better, and you will go on to find joy in life again. We will be at the end of the tunnel shining our flashlights for you!
My throat gets sore after treatments and I gargle with baking soda and salt..also i drink lots and lots of water and this seems to help. I hope the antibiotics work and that you are feeling better. Best wishes on the 7th. let us know how everything goes.
God Bless
Jackie0 -
My heart goes out to you...celinelvr said:Side Effects
Thank you guys for all your symptoms. I appreciate the time you took to get back to me.
Everything seemed good on my last onc appointment. Blood work was good -CT and bone scan was normal - except for my arthritis... My next chemo is set for March 17. Anyone have a itchy rash over the vein the chemo was given?? I am in a really bad place right now. I just brought my mother home under hospice care. She has endstage alzheimers. She has difficulty swallowing. She doesn't want tubes, etc.. She can't eat or drink anything and is mostly "out of it." She may have less than 10 days.
My heart goes out to you because I experienced the sudden loss of my father in between my chemo with cytoxan/taxotere plus neulasta shots and my radiation treatments. My dad was in hospice care for only 24 hours after six weeks of suffering with a brain injury from a fall. I know your plate is extremely full and your heart is breaking. I'm so sorry for your situaion with your mom. As for side effects, I had everyone in the book - but I'm here to tell you I finished my last chemo treatment on April 19, 2008 and I'm feeling GREAT and back to normal, whatever my normal is. You'll cope with everything - you WILL get through it. This site will help - the people here are wonderful. Hang in there. Hugs and prayers, Marilynn1 -
Taxotere and Cytoxin with Herceptin.....SIDE EFFECTS...HELP!!!!jakeca said:Cytoxan and Taxotere
I had four treatments. The first treatment, I had virtually no side effects, except I felt funny from the steroids--kind of "out of body." With each subsequent treatment, the side effects became a little bit more noticeable: nasty taste buds, achy for a few days, no energy, some minor neuropathy in my toes. Hair loss happened at the end of three weeks--right before my second treatment. I also received a Neulasta injection the day after each treatment and I really think that's what caused the aches. Usually about a week after my infusion, I felt better. The worst session was the third treatment. I think the fourth treatment was better because I was in a better place mentally--I was DONE with treatments and looking forward to feeling better permanently. I am convinced that the mind is a powerful thing.
I think you should ask your doctor about your heart pounding. I did experience some shortness of breath with the least bit of exertion, but not really a heart pounding thing.
Good luck. You'll make it and when it is all over, you will know that you have done everything possible to prevent a recurrence.
Hi. I am new to this website and am looking for anyone that has been experiencing long term side effects from Taxotere and Cytoxin.....I had stage 1 cancer with no node involvement...However, I have the Her 2 Neu type of breast cancer which is extremely aggressive and chemo was highly recommended...I don't want to scare anyone but my chemo has been done for a year and my radiation finished last April.....During the treatments, my scalp felt tight.....That has gone away but there have been some visual changes that have remained....such as blackness over the head and appearing in the brain....sounds strange but it is true....Everything appears darker than it used to....Artificial light is not as bright and when it is extremely bright and sunny outside, I will see it as bright but extremely....It is particularly frustrating to have this....Also my eyesight changed from 20/10 to 20/50 and for the first time in my life I will have to wear glasses to correct the eyesight and blurriness....I also see some strange things on TV...in other words, the tv does not appear as it used to....I really don't know what is going on but all of these effects were never present in m;y life before chemo.....
I also have had some concern with my short term memory.....and i also feel that certain levels of cognition are not present any longer.....Very very frustrating....
I have sunk into depression over all of this.....
I am wondering if ANYONE has had any of these side effects and if so please comment as I would really like to speak with you....
Thanks.....
Sweeetheart0 -
Anxious about side effectsrjjj said:been thinking of you Milly
You have had so much to deal with..your moms death and all the emotions that come with this plus the emotions of losing your hair. I have been keeping you in my prayers. There will be a time when things start to get better, and you will go on to find joy in life again. We will be at the end of the tunnel shining our flashlights for you!
My throat gets sore after treatments and I gargle with baking soda and salt..also i drink lots and lots of water and this seems to help. I hope the antibiotics work and that you are feeling better. Best wishes on the 7th. let us know how everything goes.
God Bless
Jackie
I know these posts were done a year ago so I don't know if all of you are still reading these. I am hoping I do not have some of the side effects that you all describe here. I start on 3/15/10 with my first chemo. I wonder how you all are doing now about a year later? Do you still have any side effects from the chemo? How well do you think it really worked? I was given an extra 9% less chance of recurrence with the 4 rounds of taxotere and cytozan and everyone I talk to from my doctors to my support group tells me to do it without hesitation so I am hoping it is worth doing taking the chances on the side effects.
Lorrie Balentine0 -
cytoxan and taxotere side effectsBalentine said:Anxious about side effects
I know these posts were done a year ago so I don't know if all of you are still reading these. I am hoping I do not have some of the side effects that you all describe here. I start on 3/15/10 with my first chemo. I wonder how you all are doing now about a year later? Do you still have any side effects from the chemo? How well do you think it really worked? I was given an extra 9% less chance of recurrence with the 4 rounds of taxotere and cytozan and everyone I talk to from my doctors to my support group tells me to do it without hesitation so I am hoping it is worth doing taking the chances on the side effects.
Lorrie Balentine
I just finished my first chemo infusion on friday, feb . 25th. No nausea or vomiting but felt a little giddy during the infusion. I did get high from the steroids given during the infusion and it lasted at least 24 hours....the worst for me was the muscle aches and joint pains today and last night. I looked this up and this is a side effect of the chemo on the 3rd-5th day. God! I hope it doesn't last any longer than this! I tried ibuprofen to relieve them but it wasn't as good as I thought it would be---these pains kept me up most of the night. I had Percocet from the surgery (didn't have to use it) and that has helped. I think the Neulasta shot that I got on Monday made some of these pains worse. Is anyone out there getting prophylactic antibiotic meds while on the chemo? I am on Cipro 500 mgm twice a day for the first ten days of each treatment cycle. I really appreciate all of the comments on this blog site---helped me so much to know that others had gotten through this. One down, three to go!0 -
side effectBalentine said:Anxious about side effects
I know these posts were done a year ago so I don't know if all of you are still reading these. I am hoping I do not have some of the side effects that you all describe here. I start on 3/15/10 with my first chemo. I wonder how you all are doing now about a year later? Do you still have any side effects from the chemo? How well do you think it really worked? I was given an extra 9% less chance of recurrence with the 4 rounds of taxotere and cytozan and everyone I talk to from my doctors to my support group tells me to do it without hesitation so I am hoping it is worth doing taking the chances on the side effects.
Lorrie Balentine
Hi Balentine---I have been having second thoughts about all of this with the chemotherapy----my biopsy was grade I tumor, no ducts involved, PER + and no HER---about as good as you can get. However, my oncologist sent the tissues off to a california lab, OncoDX, and more tests showed it was mildly proliferative. I have a 14% chance of recurrence without the chemo within ten years....I am 67 years old and wonder if I really expect to live 10 years or have something else get me??? Without the chemo, chance or recurrence is 5% and that pretty well answers the question.....who wants to deal with bone or brain cancer chemo when they are in their 70's? He said when it came back, he would not be dealing with breast cancer---it would be systemic. I, too, did not want to be worrying about recurrence every time I went for tests. I am a retired nurse and I remember the way chemo used to be ----pretty awful. Things have come a long way and for 4 treatments, we can get through this (wonder if I'll be saying this when my hair falls out! :>) I am glad I am not working anymore---don't know how the working women handle this. Be careful of the infections!0 -
side effectsmary s said:side effect
Hi Balentine---I have been having second thoughts about all of this with the chemotherapy----my biopsy was grade I tumor, no ducts involved, PER + and no HER---about as good as you can get. However, my oncologist sent the tissues off to a california lab, OncoDX, and more tests showed it was mildly proliferative. I have a 14% chance of recurrence without the chemo within ten years....I am 67 years old and wonder if I really expect to live 10 years or have something else get me??? Without the chemo, chance or recurrence is 5% and that pretty well answers the question.....who wants to deal with bone or brain cancer chemo when they are in their 70's? He said when it came back, he would not be dealing with breast cancer---it would be systemic. I, too, did not want to be worrying about recurrence every time I went for tests. I am a retired nurse and I remember the way chemo used to be ----pretty awful. Things have come a long way and for 4 treatments, we can get through this (wonder if I'll be saying this when my hair falls out! :>) I am glad I am not working anymore---don't know how the working women handle this. Be careful of the infections!
Dear Mary S,
To do or not to do is a decision only we can make. I am not sure what I would do if I were 67 and they told me the chemo would only give me another 9% chance that the cancer would not return. I may not decide to do it then. Most of the people on my mother's side of my family died in their 60's or 70's and I do take after that side with my high blood pressure. It is a very difficult decision because you just don't know how your body will react to the chemo. I would hate to start the chemo and then have to stop because I just could not deal with the side effects or pain but as I get closer to the start date of my first treatment which will be 3/15 all I can do is close my eyes and ask God to be with me through this as He has through my life and carry me through it....giving me His strength when mine is gone. It pretty much feels like jumping off of a dock in the dead of winter into icy waters because the dock is about to give out. You just have to pray and trust God to catch you and carry you ashore.
Lorrie0 -
chemoBalentine said:side effects
Dear Mary S,
To do or not to do is a decision only we can make. I am not sure what I would do if I were 67 and they told me the chemo would only give me another 9% chance that the cancer would not return. I may not decide to do it then. Most of the people on my mother's side of my family died in their 60's or 70's and I do take after that side with my high blood pressure. It is a very difficult decision because you just don't know how your body will react to the chemo. I would hate to start the chemo and then have to stop because I just could not deal with the side effects or pain but as I get closer to the start date of my first treatment which will be 3/15 all I can do is close my eyes and ask God to be with me through this as He has through my life and carry me through it....giving me His strength when mine is gone. It pretty much feels like jumping off of a dock in the dead of winter into icy waters because the dock is about to give out. You just have to pray and trust God to catch you and carry you ashore.
Lorrie
Hi Lorrie---thanks for the reply---I'm having a lot of joint pain and muscle aches and don 't know if these will go away as I progress after this first treatment----Keeps me up at night and I take percocet and that helps. I'm trying to stay away from the narcotics...use ibuprofen during the day. The funny thing---I never used a pain pill after the surgery but nmow this0 -
I am done with chemo. Had 4
I am done with chemo. Had 4 rounds of Taxotier and 4 of Adromycine and Cytoxin. Your side affects sound pretty typical. I lost my hair starting on day 12. Sickness did vary from dose to dose. But overall I had way more good, and really good days than bad. Best wishes to you.0 -
I had 4 rounds of Adriamycin
I had 4 rounds of Adriamycin and Cytoxin for my first chemo, and my side effects weren't too bad. Achy muscles and a bit of nausea. I'd get chemo Wednesday and by Sunday evening I was OK.
Now with Taxotere, I think I got every stinkin' side effect listed, and it's like clock work.
I just had chemo yesterday the 3rd, so I know that on Saturday the 6th, my toungue and roof of my mouth will feel like I fried it with some scalding hot soup or coffee. My first time, I literally couldn't stand up and had to crawl up my steps... my joints ached so bad that first time I felt like I had been stretched out on a rack, and it lasted all day. I basically stayed in bed that entire day. Nothing helped, it was terrible... but I called the onc nurse and they increased my steroids so that I take them for 8 days now, and it hasn't happened again, thank God. That first time, too, my legs and arms felt like they were falling asleep. I think the additional steroids have helped with that, too.
I have the painful nails, and the lifting, diarriha, constipation, really bad indigestion... and like clock work, I know when they'll happen. I will get a headache on Monday the 8th ... I get the stuffy bloody nose, my sinuses will drip... oh the joys!
I also get numb lips. Chemo is cumulative, so this is making me super tired and I have to nap a lot. My taste buds will come back by Thursday the 11. Like I said, it's like clock work with me.
Everyone is different tho, and I'm in the 10-25% for the side effects I got. Most people only get one or 2. I'm just lucky I guess!
But, let me end on a happy note. My chemos seemed to go faster and faster as I neared the end, and yesterday was my last one... so hang in there... there is light at the end of the tunnel.0 -
Ask for more steroids. I hadmary s said:cytoxan and taxotere side effects
I just finished my first chemo infusion on friday, feb . 25th. No nausea or vomiting but felt a little giddy during the infusion. I did get high from the steroids given during the infusion and it lasted at least 24 hours....the worst for me was the muscle aches and joint pains today and last night. I looked this up and this is a side effect of the chemo on the 3rd-5th day. God! I hope it doesn't last any longer than this! I tried ibuprofen to relieve them but it wasn't as good as I thought it would be---these pains kept me up most of the night. I had Percocet from the surgery (didn't have to use it) and that has helped. I think the Neulasta shot that I got on Monday made some of these pains worse. Is anyone out there getting prophylactic antibiotic meds while on the chemo? I am on Cipro 500 mgm twice a day for the first ten days of each treatment cycle. I really appreciate all of the comments on this blog site---helped me so much to know that others had gotten through this. One down, three to go!
Ask for more steroids. I had severe bone and joint pain, and they gave me steroids to last 8 days, and it helped me a lot.0 -
side effectsChrispea said:I had 4 rounds of Adriamycin
I had 4 rounds of Adriamycin and Cytoxin for my first chemo, and my side effects weren't too bad. Achy muscles and a bit of nausea. I'd get chemo Wednesday and by Sunday evening I was OK.
Now with Taxotere, I think I got every stinkin' side effect listed, and it's like clock work.
I just had chemo yesterday the 3rd, so I know that on Saturday the 6th, my toungue and roof of my mouth will feel like I fried it with some scalding hot soup or coffee. My first time, I literally couldn't stand up and had to crawl up my steps... my joints ached so bad that first time I felt like I had been stretched out on a rack, and it lasted all day. I basically stayed in bed that entire day. Nothing helped, it was terrible... but I called the onc nurse and they increased my steroids so that I take them for 8 days now, and it hasn't happened again, thank God. That first time, too, my legs and arms felt like they were falling asleep. I think the additional steroids have helped with that, too.
I have the painful nails, and the lifting, diarriha, constipation, really bad indigestion... and like clock work, I know when they'll happen. I will get a headache on Monday the 8th ... I get the stuffy bloody nose, my sinuses will drip... oh the joys!
I also get numb lips. Chemo is cumulative, so this is making me super tired and I have to nap a lot. My taste buds will come back by Thursday the 11. Like I said, it's like clock work with me.
Everyone is different tho, and I'm in the 10-25% for the side effects I got. Most people only get one or 2. I'm just lucky I guess!
But, let me end on a happy note. My chemos seemed to go faster and faster as I neared the end, and yesterday was my last one... so hang in there... there is light at the end of the tunnel.
thank you, chrispea---your comments helped me a lot---I thought I was being a "****" about the aches and pains. they are gone today and so now I know how long they will last and what to expect and will be ready with the pain pills the next time--I already have arthritis in the knees and a rotator cuff problem in the shoulder and that seemed to set those problems off seriously. Numb lips, COLD fingers and feet, and constipation (a first for me in this lifetime) and the tongue and mouth problems like you described. I guess it gets worse, too----I pray a lot!0 -
It also gets better, too.mary s said:side effects
thank you, chrispea---your comments helped me a lot---I thought I was being a "****" about the aches and pains. they are gone today and so now I know how long they will last and what to expect and will be ready with the pain pills the next time--I already have arthritis in the knees and a rotator cuff problem in the shoulder and that seemed to set those problems off seriously. Numb lips, COLD fingers and feet, and constipation (a first for me in this lifetime) and the tongue and mouth problems like you described. I guess it gets worse, too----I pray a lot!
I just randomly clicked on this thread because it looked familiar. Sure enough, there was a post from my own beloved Moopy23, dated March 4, 2009. Today - March 4, 2010, Moopy got her port removed. We're about to go out and celebrate.
You're going about this in the right way: keeping your chin up and paying attention to how the chemo affects you, so you'll have an idea of what to expect next time around. The ladies here will have lots of support to offer you, and helpful suggestions too. You *will* get through this. And the best part is that there's actually a life after chemo and rads and all that good stuff... and it's great!
Best,
Joe0 -
mouth soresChrispea said:I had 4 rounds of Adriamycin
I had 4 rounds of Adriamycin and Cytoxin for my first chemo, and my side effects weren't too bad. Achy muscles and a bit of nausea. I'd get chemo Wednesday and by Sunday evening I was OK.
Now with Taxotere, I think I got every stinkin' side effect listed, and it's like clock work.
I just had chemo yesterday the 3rd, so I know that on Saturday the 6th, my toungue and roof of my mouth will feel like I fried it with some scalding hot soup or coffee. My first time, I literally couldn't stand up and had to crawl up my steps... my joints ached so bad that first time I felt like I had been stretched out on a rack, and it lasted all day. I basically stayed in bed that entire day. Nothing helped, it was terrible... but I called the onc nurse and they increased my steroids so that I take them for 8 days now, and it hasn't happened again, thank God. That first time, too, my legs and arms felt like they were falling asleep. I think the additional steroids have helped with that, too.
I have the painful nails, and the lifting, diarriha, constipation, really bad indigestion... and like clock work, I know when they'll happen. I will get a headache on Monday the 8th ... I get the stuffy bloody nose, my sinuses will drip... oh the joys!
I also get numb lips. Chemo is cumulative, so this is making me super tired and I have to nap a lot. My taste buds will come back by Thursday the 11. Like I said, it's like clock work with me.
Everyone is different tho, and I'm in the 10-25% for the side effects I got. Most people only get one or 2. I'm just lucky I guess!
But, let me end on a happy note. My chemos seemed to go faster and faster as I neared the end, and yesterday was my last one... so hang in there... there is light at the end of the tunnel.
Dear Chrispea,
Just thought I would give you a tip on the mouth sores I saw somewhere else on this site. Use biotene mouthwash - you can get it at any pharmacy or you can also use salt and backing soda to gargle with before and after your treatments. I have been going through the posts and writing down tips to use for my upcoming chemo starting 3/15. I am going out this weekend and getting all the stuff I wrote down. They also say that since food will taste like metal or not taste very well, to suck on some lemons before eating and this will also help with the metal taste. I hope this helps.
Lorrie Balentine0 -
i also read that chewing onBalentine said:mouth sores
Dear Chrispea,
Just thought I would give you a tip on the mouth sores I saw somewhere else on this site. Use biotene mouthwash - you can get it at any pharmacy or you can also use salt and backing soda to gargle with before and after your treatments. I have been going through the posts and writing down tips to use for my upcoming chemo starting 3/15. I am going out this weekend and getting all the stuff I wrote down. They also say that since food will taste like metal or not taste very well, to suck on some lemons before eating and this will also help with the metal taste. I hope this helps.
Lorrie Balentine
i also read that chewing on ice chips during chemo helps.0 -
A year laterBalentine said:Anxious about side effects
I know these posts were done a year ago so I don't know if all of you are still reading these. I am hoping I do not have some of the side effects that you all describe here. I start on 3/15/10 with my first chemo. I wonder how you all are doing now about a year later? Do you still have any side effects from the chemo? How well do you think it really worked? I was given an extra 9% less chance of recurrence with the 4 rounds of taxotere and cytozan and everyone I talk to from my doctors to my support group tells me to do it without hesitation so I am hoping it is worth doing taking the chances on the side effects.
Lorrie Balentine
I had a lumpectomy, chemo, then radiation. I kept a detailed record of my reaction to chemo, would spend two days barely moving, then start to slowly improve till felt almost normal after 18 days or so. My reaction to first dose was so strong onc reduced it by 10%, which made a huge difference. Was also hyper with steroids so cut dosage, work with your dr to smooth things out they can't know what each individual body will do. A year later I'm fully recovered, although I think my reserves are not completely restored. But I'm getting there and you will too. Good luck!0 -
Side affects TAC and more
I have inflammatory BC, very rare (less5%)aggressive,invasive. FTR My rt breast was minor swollen, and 10 hours later it was 2x the sieze, red , hot and hard as a rock!)
Started chemo Oct1 20009
1-I could not have adrimycin due to discovery of a-fib, HR=130.
2-No troubles w/cytoxin.
3-Taxotere./taxol a whole other story, 1st was ok, 2nd infusion I stopped breathing, readmin ok, 3rd insfusion I stopped breathing, chemo stopped mastectomy moved up.
Well found desensitzation for allergies, I had to change chemos places, but they dilluted the tax, admin slowly, 1 on 1 nurse, ICU very expensive, BUT no reactions and my last treatment was yesterday!
At every infusion: I was given iv benadryll,nausea stuff,diarrhea stuff,steroids.
At home I also took stolll softener and post chemo pills for 4 days.
My issues, mostly being tired, minor joint pain, I take a non aspirin product for it, some stomach discomfort but I have a few hiatal hernias w/patch. Vision changes but advises to wait at least 2 months after chemo to get eyes checked esp to change scripts.
I followed all onco advice, rested, and yes I did work lots of hours, hydrate,proper food intake, lots of veggies.
I did go to Look Good Feel Good from ACS a few weeks ago,I'm not a make up girl, but for those that are GO! Nice $200 bag of makeup.
I did not shave my head, although I did cut it short, I did get a wig.
I di dgo to a social worker at my cancer center for all this crap. It was ok, got some anxiety issues to deal w/and sleeplessness, and who knows! This too shall pass!
I will go on lovinox the end of the month, have the mastectomy Apr 2 (if all the Dr's say GO) and follow up rads a6 weeks and w/aromasin for 5 years.
PEACE0 -
side effectsYoucandothis said:A year later
I had a lumpectomy, chemo, then radiation. I kept a detailed record of my reaction to chemo, would spend two days barely moving, then start to slowly improve till felt almost normal after 18 days or so. My reaction to first dose was so strong onc reduced it by 10%, which made a huge difference. Was also hyper with steroids so cut dosage, work with your dr to smooth things out they can't know what each individual body will do. A year later I'm fully recovered, although I think my reserves are not completely restored. But I'm getting there and you will too. Good luck!
thank you for the words of encouragement---muscle aches are gone now but now I have a couple of mouth sores and the mouth burns seriously. I used an old-fashioned remedy that I knew as a nurse but had not tried on myself----desperate, I tried it. It worked! A little baking soda in a glass of warm water---relieves the problem for awhile.0 -
Hi celinelvr
I had the same for 6 rounds. Had the same effects as you. No vomiting. I didn't have the mouth sores, just the metal taste. I also had bladder infections with burning and incontinance. I went through alot of underpants. Lost taste but not appetite. It was just a strange feeling, hard to describe. Out of body is a good description. Remember-it's temporary.0 -
I had an itchy rash when Icelinelvr said:Side Effects
Thank you guys for all your symptoms. I appreciate the time you took to get back to me.
Everything seemed good on my last onc appointment. Blood work was good -CT and bone scan was normal - except for my arthritis... My next chemo is set for March 17. Anyone have a itchy rash over the vein the chemo was given?? I am in a really bad place right now. I just brought my mother home under hospice care. She has endstage alzheimers. She has difficulty swallowing. She doesn't want tubes, etc.. She can't eat or drink anything and is mostly "out of it." She may have less than 10 days.
I had an itchy rash when I received Taxotere. It appears about 5 days later on me as a red mark, then looks more like a burn. I put Hydrocortizone cream on it.
This last time, I told the nurse about it, that it didn't happen the first time, but the second and third... the difference being that the first time, they let the regular saline drip along with the chemo so it diluted it a bit on going in, which I think prevented the injection site burn.
So, on my last taxotere treatment (last Wed) the nurse ran the chemo with the saline, and so far, I'm not noticing anything.
It goes away and doesn't seem to scar.0
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