glucose and acids
I often think about ways to effect the glucose pathways in cancer. It is true they need much more glucose. A cancer cell has 100 times the glucose receptors as a regular cell and they need every one. Someone should design a simple molecule that would fit into a glucose receptor and then seal it off for good. A patient could then get treated periodically. Like a PET scan cancer cells would absorb more of these binders than regular cell, but regular cells would absorb some. The next treatment would have to come after all the regular cells had died off, Then you could treat the cancer cells again. Since they don't die they would eventually be completely clogged with these glucose binders and then die from starvation.
Comments
-
Of Interest ?
You might want to read this, to get a better understanding of
glucose, cancer, and more of exactly what you are suggesting.
Scientific Background. Hydrazine sulfate (HS), an inexpensive, mass-produced chemical compound used for many industrial applications, was first proposed as an anticachexia agent based on its inhibition of the gluconeogenic enzyme, phosphoenolpyruvate carboxykinase (PEP CK).1,2 It was further proposed that if tumor energy (ATP) gain and host energy loss (resulting from cancer-induced excessive gluconeogenesis) were functionally interrelated—as seemed probable—HS could also, by indirect and non-toxic means, inhibit tumor growth itself.3 Early in-vivo studies demonstrated that HS could inhibit weight loss (cachexia) and tumor growth in a variety of transplanted mouse and rat models, without direct cytotoxicity,2-6 could add to the antitumor effects of chemotherapy drugs,7-9 and was free of significant side effects.10 These results strongly suggested HS as a new means of non-toxic cancer chemotherapy.11,12
Go here for the full details: Hydrazine Sulfate
SCRI0 -
I'm a freaking JeniusJohn23 said:Of Interest ?
You might want to read this, to get a better understanding of
glucose, cancer, and more of exactly what you are suggesting.
Scientific Background. Hydrazine sulfate (HS), an inexpensive, mass-produced chemical compound used for many industrial applications, was first proposed as an anticachexia agent based on its inhibition of the gluconeogenic enzyme, phosphoenolpyruvate carboxykinase (PEP CK).1,2 It was further proposed that if tumor energy (ATP) gain and host energy loss (resulting from cancer-induced excessive gluconeogenesis) were functionally interrelated—as seemed probable—HS could also, by indirect and non-toxic means, inhibit tumor growth itself.3 Early in-vivo studies demonstrated that HS could inhibit weight loss (cachexia) and tumor growth in a variety of transplanted mouse and rat models, without direct cytotoxicity,2-6 could add to the antitumor effects of chemotherapy drugs,7-9 and was free of significant side effects.10 These results strongly suggested HS as a new means of non-toxic cancer chemotherapy.11,12
Go here for the full details: Hydrazine Sulfate
SCRI
I decided to finally do a little research on my thought I just expressed. Within five minutes I found exactly what I was looking for. There is already a compound and a patent issued for that idea from 1989. The compound is Phlorizin. Now the treatment method isn't the same but the concept is the same. I looked and there hasn't been a single clinical trial. There isn't a patent on phlorizin only the treatment with it. This may be something I need to look into.0 -
Phlorizinsnommintj said:I'm a freaking Jenius
I decided to finally do a little research on my thought I just expressed. Within five minutes I found exactly what I was looking for. There is already a compound and a patent issued for that idea from 1989. The compound is Phlorizin. Now the treatment method isn't the same but the concept is the same. I looked and there hasn't been a single clinical trial. There isn't a patent on phlorizin only the treatment with it. This may be something I need to look into.
Phlorizin is a toxic 2'-glucoside of phloretin. It belongs to the group of dihydrochalcones, a type of flavonoids. It is a competitive inhibitor of renal glucose transport.[1]
http://en.wikipedia.org/wiki/Phlorizin
Glucose is an essential substrate for the metabolism of most cells. Because glucose is a polar molecule, transport through biological membranes requires specific transport proteins.
http://en.wikipedia.org/wiki/Glucose_transporter
The problem is, that this will inhibit glucose transfer of the renal system,
keeping good cells along with the cancer cells, from getting glucose.
Your body needs glucose. The cancer cells rob the body of the
needed amount, causing loss of weight, energy, and restoration.
A while back, when a family member had lung cancer, I researched a
new chemistry called "Trovax". It was developed by Oxford Biomedical,
a spin-off of Oxford U, in the UK..
It was designed to be an Immunotherapy drug, that managed to teach the
immune system to locate a protein that only a cancer cell has, and kill
that cell. It was tested with specific cancers and found to work well.
After some years of Trovax not finding funding for FDA testing,
a major chemotherapy company bought controlling interest in it.
It has failed test after test, due to it's being tested as an adjunctive
to Chemotherapy. Well.... Chemo kills your immune system, and
"Trovax" works by letting your own immune system do the work.
Is there any surprise it's failing tests?
Their web site now states that it is a drug that has been developed
to be used as an adjunctive to Chemotherapy. Odd....?
There are other viable options already in use, already being used
in other countries, and already actually helping cancer victims.
I've posted a few.... There -are- other options.
Good Health!
John0 -
This is notJohn23 said:Phlorizin
Phlorizin is a toxic 2'-glucoside of phloretin. It belongs to the group of dihydrochalcones, a type of flavonoids. It is a competitive inhibitor of renal glucose transport.[1]
http://en.wikipedia.org/wiki/Phlorizin
Glucose is an essential substrate for the metabolism of most cells. Because glucose is a polar molecule, transport through biological membranes requires specific transport proteins.
http://en.wikipedia.org/wiki/Glucose_transporter
The problem is, that this will inhibit glucose transfer of the renal system,
keeping good cells along with the cancer cells, from getting glucose.
Your body needs glucose. The cancer cells rob the body of the
needed amount, causing loss of weight, energy, and restoration.
A while back, when a family member had lung cancer, I researched a
new chemistry called "Trovax". It was developed by Oxford Biomedical,
a spin-off of Oxford U, in the UK..
It was designed to be an Immunotherapy drug, that managed to teach the
immune system to locate a protein that only a cancer cell has, and kill
that cell. It was tested with specific cancers and found to work well.
After some years of Trovax not finding funding for FDA testing,
a major chemotherapy company bought controlling interest in it.
It has failed test after test, due to it's being tested as an adjunctive
to Chemotherapy. Well.... Chemo kills your immune system, and
"Trovax" works by letting your own immune system do the work.
Is there any surprise it's failing tests?
Their web site now states that it is a drug that has been developed
to be used as an adjunctive to Chemotherapy. Odd....?
There are other viable options already in use, already being used
in other countries, and already actually helping cancer victims.
I've posted a few.... There -are- other options.
Good Health!
John
about glucose but about iron.Wife start with artemisinin,from chinese herb Artemisia annua.Princip is this:he acts with iron and cancer cells have 6-10 times more iron.Than reacts inside cancer cells,building an peroxide bridge without damaging healhy cells.Did you hear about that?0 -
Artemisiafeniks said:This is not
about glucose but about iron.Wife start with artemisinin,from chinese herb Artemisia annua.Princip is this:he acts with iron and cancer cells have 6-10 times more iron.Than reacts inside cancer cells,building an peroxide bridge without damaging healhy cells.Did you hear about that?
Or: yin chen hao 茵陳蒿
Commonly Used formulae: yin chen hao tang (茵陳蒿湯)
Sloan Kittering Reference: http://www.mskcc.org/mskcc/html/69126.cfm
Artemisia and cancer
Like any other Chinese (Asian) Pharmaceutical grade herbs, they
should not to be used without counseling from a qualified herbalist.
These are not the typical herbs one buys at the local natural foods store,
or veggie vendor.
I have found great results with Traditional Chinese Medicine, and
Asian medicine in general, but self-diagnosis and self medication
is not something generally recommended.
There is much to be learned, and much material on the Internet to
afford the learning process, if one takes the time to do so, but there
are cautions with the use of herbs of this quality. Dosages are important,
and wrong dosages can kill, just as western medicine can.
Cancer is serious business, and the treatment of it, equally serious.
John0 -
I agreeJohn23 said:Artemisia
Or: yin chen hao 茵陳蒿
Commonly Used formulae: yin chen hao tang (茵陳蒿湯)
Sloan Kittering Reference: http://www.mskcc.org/mskcc/html/69126.cfm
Artemisia and cancer
Like any other Chinese (Asian) Pharmaceutical grade herbs, they
should not to be used without counseling from a qualified herbalist.
These are not the typical herbs one buys at the local natural foods store,
or veggie vendor.
I have found great results with Traditional Chinese Medicine, and
Asian medicine in general, but self-diagnosis and self medication
is not something generally recommended.
There is much to be learned, and much material on the Internet to
afford the learning process, if one takes the time to do so, but there
are cautions with the use of herbs of this quality. Dosages are important,
and wrong dosages can kill, just as western medicine can.
Cancer is serious business, and the treatment of it, equally serious.
John
with you.I mailed dr.Singh and dr. Lai.They do research for many years and dr.Sing tell me she could take,best is 1-2 mg/kg twice a day.I also spoke with man who take it(dr Lai reccomend him)and he told me that his tumor and 4 liver mets dissapear.He take art. along with his chemo and don't know what help but...Wife is on chemo two years with any results and we must try something to maybe improve chemo.Maybe?0 -
Everything is a toxin at high enough dosagesfeniks said:I agree
with you.I mailed dr.Singh and dr. Lai.They do research for many years and dr.Sing tell me she could take,best is 1-2 mg/kg twice a day.I also spoke with man who take it(dr Lai reccomend him)and he told me that his tumor and 4 liver mets dissapear.He take art. along with his chemo and don't know what help but...Wife is on chemo two years with any results and we must try something to maybe improve chemo.Maybe?
I've known 2 people that have overdosed on water. I've looked at half dozen studies that say the maximum safe dosage is 50mg/kg 3x daily. That is a huge amount. My concern for this drugs is that it isn't a permanent block. It only lasts about 90 minutes. Wikipedia is an ok information platform but I seldom use it as my cornerstone.0 -
it looks like a product worth tryingfeniks said:I agree
with you.I mailed dr.Singh and dr. Lai.They do research for many years and dr.Sing tell me she could take,best is 1-2 mg/kg twice a day.I also spoke with man who take it(dr Lai reccomend him)and he told me that his tumor and 4 liver mets dissapear.He take art. along with his chemo and don't know what help but...Wife is on chemo two years with any results and we must try something to maybe improve chemo.Maybe?
The reason I found this product interesting is that my dads iron level has been increasing on his blood test. He has stage 4 colon cancer. I ordered the 100 mg. I found some interesting alternative treatments at
http://www.mnwelldir.org/docs/cancer1/altthrpy.htm which also talks about the Artemisinin and the Iron levels that cancer requires. My dad thinks they are just trying to sell the product. Dad doesn't do much research, I research everything. He is willing to try different things. Dad just finished the chemo pill Xeolite, I believe that is how it is spelled. His tumors have grown. The Oncologist said that wasn't working and will put him on a different chemo. He has been also drinking the Essiac tea after the chemo treatments. The doctor did said his blood was looking better then it has in a long time. Dad is trying many things. Like one person wrote on Cancer Survivors Network she had tried so many things, she wasn't forsure what cured her stage 3 colon cancer.0 -
AHCCYaziza said:it looks like a product worth trying
The reason I found this product interesting is that my dads iron level has been increasing on his blood test. He has stage 4 colon cancer. I ordered the 100 mg. I found some interesting alternative treatments at
http://www.mnwelldir.org/docs/cancer1/altthrpy.htm which also talks about the Artemisinin and the Iron levels that cancer requires. My dad thinks they are just trying to sell the product. Dad doesn't do much research, I research everything. He is willing to try different things. Dad just finished the chemo pill Xeolite, I believe that is how it is spelled. His tumors have grown. The Oncologist said that wasn't working and will put him on a different chemo. He has been also drinking the Essiac tea after the chemo treatments. The doctor did said his blood was looking better then it has in a long time. Dad is trying many things. Like one person wrote on Cancer Survivors Network she had tried so many things, she wasn't forsure what cured her stage 3 colon cancer.
We also buy AHCC and she combine these two.Artemisinin is cheap and I think they don't try to sell it.Wife was taken BIOBRAN for 6 months and I think she have better results with FOLFOX,less side effects at least.Nobody knows is it gonna work(artemisinin) but I pray anything to work:chemo or some of these supplements or both together.0 -
Me too...we just need to keep researchingfeniks said:AHCC
We also buy AHCC and she combine these two.Artemisinin is cheap and I think they don't try to sell it.Wife was taken BIOBRAN for 6 months and I think she have better results with FOLFOX,less side effects at least.Nobody knows is it gonna work(artemisinin) but I pray anything to work:chemo or some of these supplements or both together.
Dads doctor put him on the pain patch morphine. I don't know where dad is having pain. I do know that pain pills become addictive and if you stop taking them, they will make the body feel a great deal of pain.. He looks sad. I guess it was severe depression of the tumors growing. I did read several places that sometimes tumors expand before they go down...it made mom and I sick to read it also. I am not giving up on dad. We got to keep trying....I can't imagine how dad feels.
The doctor said he had 9 months without the chemo. That is why he is choosing to take it. Dad didn't say if the doctor gave him a timeline with the chemo and I didn't ask.. I don't know where dad is having pain. I pray that Gods gives wisdom to find a working treatment.
I made 4 32 oz batchs of extra strong essiac tea today, juiced, 7 bitter apricot seeds and gave him zeolite, I told him those tumors weren't going to grow on my clock. AS soon a the Artemisinin comes in he wants to try it. I am glad there are people out researching other options that might work. And if they make money doing it. Good for them. I am glad alternatives are affordable. Its strange how his blood work is looking better, but the tumors are growing..there is a saying that life is in the blood. I don't think the chemo would make the blood cells normal. He was taking a very expensive shot to increase the blood cells which now the doctor didn't think he needed after chemo. It must be the essiac tea, because that is the one new thing we just started using. Mom takes it too. She has high sugar. She tested her sugar level and its the lowest its been in a long time....so I am getting a little evidence that something is working to go along with the faith.0 -
ArtemisininYaziza said:it looks like a product worth trying
The reason I found this product interesting is that my dads iron level has been increasing on his blood test. He has stage 4 colon cancer. I ordered the 100 mg. I found some interesting alternative treatments at
http://www.mnwelldir.org/docs/cancer1/altthrpy.htm which also talks about the Artemisinin and the Iron levels that cancer requires. My dad thinks they are just trying to sell the product. Dad doesn't do much research, I research everything. He is willing to try different things. Dad just finished the chemo pill Xeolite, I believe that is how it is spelled. His tumors have grown. The Oncologist said that wasn't working and will put him on a different chemo. He has been also drinking the Essiac tea after the chemo treatments. The doctor did said his blood was looking better then it has in a long time. Dad is trying many things. Like one person wrote on Cancer Survivors Network she had tried so many things, she wasn't forsure what cured her stage 3 colon cancer.
When the wormwood herb contains artemisinin, it is in one of three forms (some naturopaths use all three, others a combination of two):
A water soluble form called artesunate which is the least toxic and most active, yet has the shortest life in the body (being water soluble it passes through),
Artemether is a lipid (or fat) soluble form with the longest life in the body, but also the most toxic form when used in high doses (which are seldom needed). Artemether can cross the blood brain barrier.
Artemisinin is the active compound of the plant. It too can cross the blood brain barrier and is very safe.
Because of artemisinin’s activity, because it attacks using free radicals to destroy the cell membranes of cells carrying iron, it is not recommended to take antioxidants with artemisinin. However, this doesn’t mean that hydrogen peroxide therapy, ozone therapy, or any of the oxygenation therapies cannot be used with artemisinin to help create an environment in which cancer cells cannot live and begin to self destruct. In fact, many other therapies are suggested when using artemisinin.
Warnings
High doses are neurotoxic (bad for the brain) . People experience trouble walking, problems with nerve and the spinal column and pain response, respiration slows, gets depressed, and cardiac arrest in large animals has been witnessed, but under very high doses.
In humans, so far only one person has had a serious side effect, which was referred to as a "first-degree heart block." It is assumed that doses up to 20,000mg per 70kg male is a safe dosage, although long-term toxicity is not known at this time.
We do know the following:
Do not take artemisinin or any derivates within 20 days of radiation therapy. Radiation spreads iron (leaks) to surrounding tissues.
If iron levels are low, supplementing iron for a few days prior to starting this treatment is recommended.
Laboratory tests should be used to monitor the progress of this therapy: Complete Blood Count, reticulocyte count (will drop initially but comes back after a few weeks), liver function, ferritin levels, Total Iron Binding Capacity, Erythrocyte Sedimentation Rate, C reactive protein, and appropriate tumor markers. Tumor markers might increase during the initial stages of tumor breakdown.
Therapeutic levels (dosages) for those with active cancers can be 1,000 mgs per day, divided into 4 parts), while some physicians recommend 1,600mg per day based upon a 100 pound female. It is a "cooling" herb according to Traditional Chinese Medicine. If you find yourself tingling (too cool) you might want to drop the dosage a bit.
Artemisinin should be taken with fatty foods. Using an essential fatty acid (flax oil, cod liver oil, lecithin, wheat germ oil) will help absorption, as will CLA.
Artemisinin is not considered a "stand-alone" cancer cure, but part of an overall, aggressive, anti-cancer program. High doses of pancreatic enzymes (on an empty stomach), CoQ10 supplementation, detoxication programs and lab work should all be employed when using artemisinin.
Source: Artemisinin0
Discussion Boards
- All Discussion Boards
- 6 CSN Information
- 6 Welcome to CSN
- 121.9K Cancer specific
- 2.8K Anal Cancer
- 446 Bladder Cancer
- 309 Bone Cancers
- 1.6K Brain Cancer
- 28.5K Breast Cancer
- 398 Childhood Cancers
- 27.9K Colorectal Cancer
- 4.6K Esophageal Cancer
- 1.2K Gynecological Cancers (other than ovarian and uterine)
- 13K Head and Neck Cancer
- 6.4K Kidney Cancer
- 671 Leukemia
- 794 Liver Cancer
- 4.1K Lung Cancer
- 5.1K Lymphoma (Hodgkin and Non-Hodgkin)
- 237 Multiple Myeloma
- 7.1K Ovarian Cancer
- 63 Pancreatic Cancer
- 487 Peritoneal Cancer
- 5.5K Prostate Cancer
- 1.2K Rare and Other Cancers
- 540 Sarcoma
- 734 Skin Cancer
- 653 Stomach Cancer
- 191 Testicular Cancer
- 1.5K Thyroid Cancer
- 5.9K Uterine/Endometrial Cancer
- 6.3K Lifestyle Discussion Boards