Bone biopsy

I just completed a PET/CT scan and bone scan, each radiologist report said the cancer had spread to my rib bones. Then I went to the oncologist on Friday and he said maybe the scans are not accurate - and told me to schedule a bone biopsy. I'm sort of hopeful but mostly confused. I know I just need to wait for the biopsy (sometime this week I hope) but if any of you have had all three scans turn up negative and then the biopsy came back showing no cancer - let me know so that I can emphasize the hopeful part while I wait for the biopsy. Thanks for all replies.

One more question: if I do have to do chemo again, is the second time easier?

Susan