Promising Treatment for those with aggressive colon cancers or for those who are out of options

polarprincess
polarprincess Member Posts: 202 Member
edited March 2014 in Colorectal Cancer #1
i haven't been on here in awhile so i apologize if this has already been posted, but some of the medical community that i am friends with thought it exciting, so I though i would post for you all to check out:

Nashville, Tenn. (Vocus/PRWEB ) October 8, 2009 -- A patient who had inoperable, stage 4, colon cancer is free of any detectable malignancy after using a new treatment offered by NeoPlas Innovation. All evidence of disease was gone four months after he began the lovastatin and interferon combination. Now six months into treatment, he remains free of any signs of cancer, and all previous digestive symptoms have been resolved. He is tolerating the treatment well; his only side effect is minor fatigue.

The patient, who is in his late fifties, was diagnosed with extensive cancer of the lower colon in early 2008. Initially his doctors recommended an operation to remove all the organs of his lower abdomen and pelvis. They abandoned this option, however, after determining he would have been unlikely to survive the procedure. Chemotherapy was tried but was ineffective. He visited NeoPlas Innovation's Nashville clinic in the spring of 2009 and began its outpatient treatment.

The treatment he's using was developed by Dr. Stephen Cantrell to battle his own malignant melanoma in 2000. Then a 33-year-old craniofacial and maxillofacial surgeon, Cantrell fought his recurring cancer with multiple surgeries, a cancer vaccine's clinical trial and interferon. After these failed to stop the aggressive malignancy's spread, the surgeon was told he had six weeks to live.

Refusing to accept that prognosis, he searched the medical literature for anything that was new or overlooked. He made an educated guess about trying a combination of lovastatin and interferon. Because of his terminal prognosis, he did something he would never ask of a patient. He experimented on himself with an untested treatment, keeping careful notes and becoming the guinea pig.

After four weeks of the combination, scans showed no remaining evidence of tumors from his melanoma. That was nine years ago, and there has been no evidence of cancer since. (He continues to take low, maintenance doses of both medicines.)

Patients with other cancers began requesting the new drug combination soon after Cantrell's recovery. Continuing to see its potential in those patients, Cantrell left his surgical practice to devote his career to developing the treatment.

Patients from 28 states and four countries have now used the new combination with promising results. They are being treated for extremely aggressive cancers, such as pancreatic, colon, renal, some sarcomas, mesothelioma, melanoma and others. Eventually Cantrell hopes to implement formal clinical trials, but helping individuals remains his priority.

The treatment's medicines have the advantage of being safe and well tolerated. Most patients never experience effects commonly affiliated with chemotherapy or radiation (nausea, vomiting, hair loss, bone marrow suppression or immune system suppression).

NeoPlas Innovation's web site, www.neoplas.org, provides detailed information about the treatment. Additionally, the clinic can be reached at (615) 371-8100.



http://www.neoplas.org/home.html

Comments

  • Shayenne
    Shayenne Member Posts: 2,342
    Oh My!!!
    This sounds so promising! I wonder what my onc would say about this, I may show her it and see what it says, if anything, I want to go to Nashville!! Thanks for this Princess!

    Hugsss!
    ~Donna
  • John23
    John23 Member Posts: 2,122 Member
    Immunotherapy
    TroVax® cancer immunotherapy

    TroVax is Oxford BioMedica's leading cancer immunotherapy product. It is designed specifically to stimulate an anti-cancer immune response and has potential application in most solid tumour types. TroVax targets the tumour antigen 5T4, which is broadly distributed throughout a wide range of solid tumours. The presence of 5T4 is correlated with poor prognosis. The product consists of a poxvirus (MVA) gene transfer system, which delivers the gene for 5T4 and stimulates a patient's body to produce an anti-5T4 immune response. This immune response destroys tumour cells carrying the 5T4 protein.

    In 85 patients treated to date, TroVax has been safe and well tolerated, and induced a strong anti-5T4 immune response. In the completed Phase I/II trials, the immune response correlated, with high significance, to time to disease progression, which translated into a correlation with improved overall survival. Data from four ongoing Phase II trials have been encouraging and confirmed the relationship between the anti-cancer immune response stimulated by TroVax and tumour responses in patients. Further trials including Phase III trials are planned.


    http://au.sys-con.com/node/148700#
  • dianetavegia
    dianetavegia Member Posts: 1,942 Member
    Polar Princess
    That sounds wonderful! Hope that can help many of our members.
  • dianetavegia
    dianetavegia Member Posts: 1,942 Member
    Side effects of this treatment
    My friend's father has extensive melanoma that has spread into his bones. He's had this treatment but had awful side effects. You can read about them at www.wdorrell.blogspot.com at the start of the threads. Woody is doing another trial now.
  • Fight for my love
    Fight for my love Member Posts: 1,522 Member
    Thank you guys for providing
    Thank you guys for providing these information.Hope the new method will save more people's life.
  • Buzzard
    Buzzard Member Posts: 3,043 Member

    Thank you guys for providing
    Thank you guys for providing these information.Hope the new method will save more people's life.

    All my surgeries and care was in Nashville......
    Can't say enough good things about it........
  • lisa42
    lisa42 Member Posts: 3,625 Member
    great info
    Hi Polarprincess,

    I didn't even see your post when I posted my own thread about Dr. Cantrell and the Neoplas Innovations. Sorry- didn't mean to steal your topic- I should have scrolled further down first. Hopefully people will see your post and/or mine or the mention Buzzard made about it in another thread. It's got me excited about looking into it. Of course, I'm hoping I'll do well on what I'm on now (Folfiri), but I have my doubts and my CEA is creeping up again.

    It's always nice to know there are other options out there. It gives us hope and we all have to spread the word!

    Cheers,
    Lisa
  • lisa42
    lisa42 Member Posts: 3,625 Member

    Side effects of this treatment
    My friend's father has extensive melanoma that has spread into his bones. He's had this treatment but had awful side effects. You can read about them at www.wdorrell.blogspot.com at the start of the threads. Woody is doing another trial now.

    Diane- which treatment?
    Hi Diane,

    Which treatment are you referring to with your father's friend having "awful side effects"- the one polar princess mentioned with Dr. Cantrell or what was just mentioned above by someone else?

    Lisa
  • Buzzard
    Buzzard Member Posts: 3,043 Member
    lisa42 said:

    great info
    Hi Polarprincess,

    I didn't even see your post when I posted my own thread about Dr. Cantrell and the Neoplas Innovations. Sorry- didn't mean to steal your topic- I should have scrolled further down first. Hopefully people will see your post and/or mine or the mention Buzzard made about it in another thread. It's got me excited about looking into it. Of course, I'm hoping I'll do well on what I'm on now (Folfiri), but I have my doubts and my CEA is creeping up again.

    It's always nice to know there are other options out there. It gives us hope and we all have to spread the word!

    Cheers,
    Lisa

    Im sure PP won't mind......
    Good advancement news makes everyone giddy....Im sure she doesn't mind at all...Hopefully it is another step towards a cure........Good Luck to all of you, Clift
  • polarprincess
    polarprincess Member Posts: 202 Member
    Buzzard said:

    Im sure PP won't mind......
    Good advancement news makes everyone giddy....Im sure she doesn't mind at all...Hopefully it is another step towards a cure........Good Luck to all of you, Clift

    hi
    of course i don't mind..the more posts about it hopefully the better chance more people will see it.