Question about Clinical Trials

lizbiz
lizbiz Member Posts: 120
edited March 2014 in Colorectal Cancer #1
Hi everyone,

First, I'd like to thank everyone for the well-wishes before my scans. Unfortunately, after 10 rounds of FOLFIRI+Avastin, the tumors grew (albeit, marginally...but still). Anyway, I'm now erolled in a clinical trial for a MEK inhibitor drug called AZD6244.

My question is - have any of you been involved in a clinical trial? If so, how did it go?

Thanks again to everyone!

Hugs and prayers,
Elizabeth

Comments

  • SandyL
    SandyL Member Posts: 218
    #2
    Can't help
    with info about the clinical trial you are going to be in, but I want to say I'm sorry that you are having a re-occurance. I sure hope the clinical trial and treatment will work for you.
    Sandy
  • tootsie1
    tootsie1 Member Posts: 5,044 Member
    #3
    Sorry
    Elizabeth,

    I'm really sorry your news wasn't better, but I'm really glad you got in a clinical trial. I'll be praying for excellent results from that.

    *hugs*
    Gail
  • Buzzard
    Buzzard Member Posts: 3,043 Member
    #4
    tootsie1 said:

    Sorry
    Elizabeth,

    I'm really sorry your news wasn't better, but I'm really glad you got in a clinical trial. I'll be praying for excellent results from that.

    *hugs*
    Gail

    Cousins Clinical Trial...
    My cousin was diagnosed with breast Cancer 10 years ago with advanced stages and was told that she wouldn't last very long. She took complete control and got in a clinical trial and flew back and forth to I think Sloan Kettering for her treatments ( I could be wrong on the place), she is 10 years out and still going strong. She was her own advocate and she doesn't take no for an answer...She also was involved in some type of airfare arrangement that she could use the Drs plane if it wasn't being used. Im not sure but it was a very good outcome out of a distraught situation for her.

    Clinical trial saved her life........
  • tammy41
    tammy41 Member Posts: 48
    #5
    i was on cpt 11 and erbartux
    i was on cpt 11 and erbartux and then i started to have more spots show up so i went to mass general last week and started on a clinical trial. it is the panitumumab it is the erartux but it is 100 percent humanized. the treatment was for 1 hr no premeds. i feel great. the next treatment will be in 2 weeks but i have to go every week for blood work. i was getting alittle nervous because i was not getting any side effects but this morning i woke up with a red face and i was glad[im a sick women to want some kind of side effect]but that for some reason makes me feel like its working.i have been wondering how you made out last week and i didnt see you post all week. i wish you the best of luck and when i found out i was going to be in a trial i was really scared but the people on this site helped alot take care tammy
  • Wenchie
    Wenchie Member Posts: 88
    #6
    Clinical Trials
    Hi Liz:
    I'm in a clinical trial but it's a double-blind study so neither I nor my Oncologist know if I'm getting "the real thing". I'm on "hedgehog", a pill, once daily, no side effects.
  • Glv49
    Glv49 Member Posts: 206 Member
    #7
    I don't have any experience
    I don't have any experience with clinical trials.. but I wish you all the luck in the world.

    Gail
  • ADKer
    ADKer Member Posts: 147
    #8
    Glv49 said:

    I don't have any experience
    I don't have any experience with clinical trials.. but I wish you all the luck in the world.

    Gail

    Clinical trial
    I did a clinical trial but it was an older one that I believe they needed to finish up. I believe that they already knew the effectiveness of the chemo cocktail. I received irinotecan and oxaliplatin plus FUDR (a potent form of 5FU) through an HAI pump. None of these are novel therapies and even the combination is not novel. It is a very postent conbination as you might guess but I had quite advanced metastasis to my liver and going at it very aggressively was probably the only hope I had of getting to liver resection, which I did in about 6 months.

    Maybe someone with more knowledge can expand on this but I believe that clinical trials are classified as phase I, II or III. With a phase I trial, the effectiveness of the therapy may not be known. With a phase II trial, there is already some evidence of effectiveness and they are trying to determine optimal dosage. With a phase III trial, they are trying to compare the effectiveness of the new therapy with the current standard of treatment.

    Do you know the phase of the clinical trial that you are enrolled in?

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