Re: tamoxifen

aussie59
aussie59 Member Posts: 48
edited March 2014 in Ovarian Cancer #1
Hi Everyone!

Iam new here.I found this site a few months ago and have been impressed with the knowledge and information I gained. I was diagnosed in 2/2002
with Stage 111c (serous Papillary).My ca125 was 1500. I underwent optimal debulking,retrograde hysterectomy,BSO and omentectomy along with debulking. In April 2002I had 6 treatments of paclitaxel/carbonplatin. In Sep 2003 I commenced 6 treatment of Carboplatin/Caelyx. In June 2005 I commenced 28 treatments of Radium(my ca125 continued to get higher very slowly)In May 2006 I commenced taxotere/gemzar (did not work)
I was then put on Topantecan (did now work) so I was then put on Paclitaxel/Carboplatin for 9 treatments but my ca125 is still 356. My new gyn/onc has now suggested tamoxifen and he said that the paclitaxol/carbo will be replaced with cyclophosphamide. Can anyone tell me what side effects I can expect from tamoxifen. Has anyone had any experience with cyclophosphamide.
Thanks. Irene

Comments

  • mopar
    mopar Member Posts: 1,972 Member
    #2
    Irene:
    I'm sorry I can't answer your questions, but I'm sure you will get some good responses from others here. I just wanted to let you know that I'll be praying for you and thinking of you as you begin another course of treatment. There are so many here that have experienced what you are going through, so you have come to the right place for lots of hug, support and information. Keep us informed and visit when you can!
    Monika
  • BonnieR
    BonnieR Member Posts: 1,526 Member
    #3
    Welcome Irene, I like yourself have tried many combos, some giving me a break others not. I haven't had cyclophosphamide but am sure you'll find someone here who has. If not you can contact someone through ACS and get more information. Prayers N Hugs BonnieRose
  • floridajo
    floridajo Member Posts: 480
    #4
    I know a few women on another site that said Tamoxifen was pretty easy to tolerate. Some minor fatique and minimal nausea. I'll be praying that it works for you as well. (((hugz))..Joanne
  • saundra
    saundra Member Posts: 1,370 Member
    #5
    No experience to offer but I will add you to my prayers and keep us newcomers posted. I was only dx in March 2007 and have chemo before surgery (taxol and carbo). Hugs to you for sharing.
  • tishthefish
    tishthefish Member Posts: 2
    #6
    Hi all!
    Iam new here. I just found this site and I like what I have seen. I hope to be able to confer with others with the same cancer I have. (I refuse to call it "my cancer") I was diagnosed after exploratory surgery 4/4/06, with Stage 3c Primary Peritoneal Cancer, which is very similar to Ovarian Cancer and is treated the same way. I was given a hysterctomy of all except cervix and a lot of debulking was done. My Ca125 was not very high, but at 71 it was not "normal" I went through 6 cycles of paciltaxel/carbonplatin. I am now in remission.

    However, I am experiencing similar symptoms as before surgery and the numbers are creeping up 6-9 points each time lab work is done. My last CT was 2 weeks ago and is inconclusive. Not much changed from one done 3 months ago.

    My dr said if my numbers keep going up, next appt. at end of August, we will discuss a clinical trial with Thalidomide vs Tamoxifen. Does anyone know about this trial? How are these drugs given? What are the side effects?

    Last but not least, I of course, lost ALL my hair during chemo and it all has grown back except my eyelashes. Well, they did grow back at first, and then I just started loosing them like crazy! I have stopped curling and using mascara. But, this is driving me crazy! My eyelashes were my prized possessions! hee. Anyone have any ideas?

    Anyway, Iam glad I found you all and I send you all my blessings and prayers along with bunches of hugs! Tish

Discussion Boards