Has anybody took Zejula Chemo pills for maintenance.

i have been on Zejula since Aug 2018. 200 mg. Aside from some sleep disturbance, I haven't had any bad side effects. Although for several months I have a stuffy head, sneezing, and constantly blowing my nose. I'm wondering it it's the Zejula. The package insert says some people experience this. Also have elevated blood pressure. 

My doctor in Florida where I had my Chemo and surgery wants me to take Zejua. Right now I am cancer free. She says it is now used on Patients who have responded to treatment to push back a reoccurance of the cancer.

I am back in Illinois now and my doctor says I should not take Zejua, I should just enjoy my life. THat I don't need a chemo drug a I have gone through so much.

I don't know what to do?

I started it last month. At first I felt fine except for a little trouble going to the bathroom but now I have mild joint pain and stiffnes and fatigue.  I have also developed bruises on my legs.  Honestly, I'd rather have all of that then get cancer again so I'll keep taking it as long as my doctor recommends.

I have been on Zejula for a week now. Side effects I noticed is Dry Mouth, ans not sleeping well, waking up and not going back to sleep.

My knee bother me, I have high Blood pressure so record that.

I have been on Zejula for three months.  I had an initial increase in blood pressure but that was temporary.  It is normal now.  I do have some joint pain but at 61 it is difficult to tell whether it is age related or medication related.  I have had hot flashes since I have been taking it.  I never had hot flashes like this when I went through menopause.  Initially I had a slight bit of nausea but that passed aftert a while.  This is much better than Lynparzza.  I had terribly elevated liver enzymes with that one.  Give the Zejula a chance.  The nurse at Biologics told me many of the side effects are temporary.

Hi, Ladies!

I normally "hang out" on the uterine board, but I read here. I'm was diagnosed with Fallopian tube originally and then "secondary peritoneal" after my second surgery for staging. I was Stage 2 with endometriod adenacarcinoma. 

Only recently has my GYN/ONC mentioned maintenance, specifically Zejula, and it kind of freaked me out. All along he has said, "You're fixable," and optimum debulking with surgery got it all, except maybe microscopic cells, and "Chemotherapy would get the rest. And you can go on and live your life!" I thought I was going to be "done" after my last round of chemo, and being on a serious maintenance drug isn't "done!"

I really appreciate y'all describing your experiences with this drug. Any input is very helpful. I'm going to have to make a decision in the next two months. 

Good Luck to All,

Alicia

Hi, Michellemoniq88,

You might notice I posted on this thread a month ago, and you are the first person to write anything. I have scoured several of the boards and can find very little info about Zejula. From what I can tell, it's very different for everyone. I'm sorry to hear you thought it was worse than chemo...and ironic that what my chemo nurse told me was that, "It's not chemo. You won't be sick like you have been." 

I don't know what kind of cancer you had, but mine was/is endometriod adenocarcinoma, Stage 2, Type 2, so I think my chance of recurrence is only about 30%. It's a terrible decision to make....whether to take this drug or not. What I've thought so far is that I would try it. Some people on these boards report that they are fine with it. I know that I can't continue to live as I have on chemo (I just finished round 6 two weeks ago). ...cuz that's NOT living. I just had my post-treatment CT last week and am waiting for results. The Zejula or not decision will come in about 8 weeks.

I wish the best for you. And I hope some other women will respond here.

Best, A

I'm supposed to start taking Zejula the first week of June. I'm not happy about it and very scared of side-effects. I asked my nurse..."So every thing I've read people who have actually taken the drug are 1) either really, really sick and descibe it as "worse than chemo" or 2) they're fine with it. It's black or white, no gray. Is that kinda true?" She said it was.

I asked.... so since my bloodwork held up so well with chemo was that also likely to be true with Zejula? She said it was.

I feel like I have to try it. Fingers crossed.

Ket us know if you take it and how you do. Good wishes & luck

Alicia

I started Zejula in Dec, had to come off several times for low platelets and then covid. I was on it 2 weeks straight out of 10 weeks. Now recurrence and off it. Doctor says I’m platinum resistant and we will talk next week! Ovarian 3 c! Anyone with this????

I was diagnosed with Stage 4 Fallopian Tube Cancer is 2022. I started Zejula in Jan., 2023, after infusion chemo. The standard dose is 200mg daily but I started to get severe body tremors so my oncologist decreased it to 1/2 the dose. I relocated from NJ to MN in early 2024 and started my oncology care at Mayo Clinic. My new oncologist wanted to to try and go back to the standard dose but my body just cannot tolerate it so I will remain on 1/2 of the dose. My most recent CT scan showed signs that there may be active cancer again so I am getting prepared for my 2nd round of chemical chemo.

I am just looking for support.