Uterine Cancer Stage 4

You’re in a very stressful position right now, but please keep in mind that there are a number of new therapies that weren’t available just a few years ago. I agree with Forherself about having some genomic/genetic testing done to determine which treatments might be most effective for you, if this hasn’t already been done.

And while we’re excited that new treatments are now available, I just want to remind you that conventional therapies can also work for some people. I’m still NED almost five years after treatment ended for an aggressive form of uterine cancer. And my mother struggled for several years with cervical cancer that spread to other parts of her body, despite different chemos and multiple surgeries. However, a new doctor wanted her to try a newly approved chemo (this was back in the 1980s) and she agreed. Notwithstanding the odds, that new chemo worked and when she died some years later from other causes, she was still cancer free.

Please keep us posted on what the doctors recommend as your steps and ask any questions you may have. We’re here for you.

Sorry to hear about the diagnosis. It is a very stressful. Your situation is very similar to my mother, who is currently undergoing treatment. However, she had to have a full open surgery (originally it was planned to do a complete robotic hysterectomy). Her cancer started in the uterus and there were evidence of the disease that gone spread to the tubes, ovaries, etc, which were removed. They removed 10 pelvic lymph nodes of which none had cancer and removed a bit of the omentum as well as there were evidence of cancer there. Pathology report staged her at diagnosis at 4, UPSC, which is the more aggressive and rare type of endometrial cancer. Surgery was a success and they claim the got everything. However, because of its stage, it was recommended she go through six cycles of chemo, the combo of carbo/taxol plus Herceptin. Six cycles done, and she was deemed "cancer free," if that's even a thing. 3 months later post chemo visit, she went to her doctor for an exam and her doctor found some vaginal tissue scaring, which was biopsied and determined to be a recurrence. Long story short, a CT scan was done and we later found there were some new lesions concerning for metastatic disease as well as omental disease/mesenteric lymphadenopathy. I don't know what to expect at this point. The next line of treatment that's recommended is an oral target therapy treatment as well as an immunotherapy (combo of pembrolizumab/lenvatinib). We're hoping these would control and stop the cell growth. Trying to remain hopeful and it hurts to see someone you love go through this. 😥

Keep us posted on the doctor's recommendation! We all have each other for moral support.

I'm new here and also have stage 4 endometrial cancer. I found a program by Chris Wark on ChrisBeatCancer.org. It is called Square One. It has been amazing for me and through them I found another organization called HealingStrong.org. You might want to check these out as they can help along with conventional treatments. Many people are healing their advanced cancers naturally! Hang in there. I know how you feel. Sending prayers.

Hi all, my 67 year old mother got diagnosed with high grade serous adenocarcinoma a few months ago. It is stage 4 because it metastasized to liver and lymphnodes (mostly abdominal and some paraaeortic) Her scans after 4th round of carbo/taxol showed great response so far and now surgeon will decide if surgery will happen after 6 or 8th chemo.

Im thinking if we can treat with chemo as much we can before surgery would be better?

Can they remove lymphnodes throughout the body?

Anyone with similar experience? I would greatly appreciate your learnings.

hugs and love,

ghernand

Sorry to hear about your mother and what she is going through. I know how hard it is on you both! Just remain positive and be strong! That's the plan...for the immunotherapy drugs to work alongside the immune system to help prevent the spreading and growing of existing cancer cells. We were hoping the surgery and chemotherapy would catch everything but given how aggressive (and rare) USPC is, it was likely that a recurrent would occur.

Hi Ottobar! My mom has stage 4 - just finished her 5th chemo and it’s not so bad. She hasn’t had surgery yet. That’s coming soon. Out of the 5, the first one was the toughest one and what I mean by that is that she had a few days that felt like the flu and then she was back to normal. Drinks lots of water before and after each treatment. The worst part for her was the constipation but after a few days she was fine. She did take something to help with that. There were 2 days where she didn’t eat much so we bought her electrolyte water to help keep her hydrated - this helped. She drank a lot of chicken soup too during those days to keep her protein intake.

you can do it!

hugs and love

gleidys

@ghernand We haven't considered any clinical trials yet. We are waiting to see how she responds to keytruda + lenvima. She's starting week 3 on keytruda/lenvima; so far, surprisingly no side effects. Tolerating really well, which is promising. We're hoping this treatment further shrinks, prevent from further growth, if not, eliminates the tumor(s) all together.