More articles

Vitamin D again (second to, or perhaps equal to exercise, in my opinion Vitamin D is the best non-chemo strategy to combat colon cancer): https://www.sciencedirect.com/science/article/pii/S0960076018302954?via=ihub

[C]alcitriol [Vitamin D] has an array of potential protective effects against CRC by acting on carcinoma cells, CAFs, immune cells and probably also the gut microbiota.

Vitamin D and African Americans: https://www.ncbi.nlm.nih.gov/pubmed/29964038

We found vitamin D to increase expression of UPP1, leading to reduce uridine-induced DNA damage, in colon cells and organoids. A polymorphism in UPP1 found more frequently in African Americans than European Americans reduced UPP1 expression upon cell exposure to 1α,25(OH)2D3. Differences in expression of UPP1 in response to vitamin D could contribute to the increased risk of CRC in African Americans.

Acai: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0200101

The results of this review suggest that açaí is safe and can be used as a chemoprotective agent against cancer development. Açaí therapy may be a novel strategy for treating cancer.

Less soda and red meat, more fish:  https://www.wjgnet.com/1007-9327/full/v24/i24/2617.htm

A better adherence to the [Mediterranian Diet], specifically low intake of sugar-sweetened beverages and red meat as well as high intake of fish, is related to lower odds for advanced polyps.

How necessary is follow up? http://kjim.org/journal/view.php?doi=10.3904/kjim.2018.204

[M]ore evidence is needed to prove that monitoring CRC patients intensively after curative resection improves overall survival. Overly intensive surveillance such as CT scans every 3 months should be avoided until evidence warrants otherwise. However, considering that the purpose of surveillance of CRC is to identify patients with metachronous disease who may be good candidates for curative resection, intensive surveillance can be justified in high-risk patients and stage IV resected patients.

Another side effect of chemo? https://www.ncbi.nlm.nih.gov/pubmed/29957058 (abstract only):

Chemotherapy reduces tumor burden by inducing cell death; however, the resulting dead tumor cells, or debris, may paradoxically stimulate angiogenesis, inflammation, and tumor growth.

Curcumin (Tumeric) again.  It seems to be the "hottest" supplement out there: https://www.ncbi.nlm.nih.gov/pubmed/29956726 (abstract only):

the present data demonstrated that curcumin attenuated resistance to chemotherapeutic drugs through induction of apoptosis of CSCs among colon cancer cells. These findings may provide novel evidence for the therapeutic application of curcumin in CRC intervention.

And again: https://www.ncbi.nlm.nih.gov/pubmed/30097113

Turmeric extract was demonstrated for the first time for its anti-tumor and anti-metastatic effects in both colorectal cancer cells and orthotopic mouse model through regulation of multiple targets. These findings strongly suggested the promising use of turmeric extract as chemopreventive or chemotherapeutic agent for colorectal cancer patients with metastasis.