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SandiaBuddy
SandiaBuddy Member Posts: 1,381 Member
edited June 2018 in Colorectal Cancer #1

Have some red rasberries on your breakfast: https://academic.oup.com/jn/article/148/5/667/4979589

[Red rasberry] supplementation reduced DAI score and the risk of CRC development during recurring colitis in mice, suggesting that RB is a possible dietary supplement for patients with ulcerative colitis and related gut inflammatory diseases.

And watch that blood sugar: https://www.spandidos-publications.com/etm/16/1/222/download

hyperglycemia promotes EMT, proliferation, migration and invasion in CRC cells and may provide novel insights into the link between HG and CRC.

Nuts, again!  https://www.ncbi.nlm.nih.gov/pubmed/29904634

In summary, these data demonstrate that walnuts confer significant protection against intestinal tumorigenesis and growth and preserve ISC function in the context of a high-calorie diet and obesity. Thus, these data add to the accumulating evidence connecting walnuts as a potentially effective dietary strategy to break the obesity-colon cancer link.

Comments

  • Annabelle41415
    Annabelle41415 Member Posts: 6,742 Member
    edited June 2018 #2
    Yup

    Saw this in an article too.  The thing that bothers me about rasberries is the seeds - it just doesn't agree with me and they always get stuck in my teeth LOL.  Said this was excellent to keep you regular.  If they came out with seedless berries like they do grapes I'm all in Laughing.

    Kim

  • Mikenh
    Mikenh Member Posts: 777 Member
    edited June 2018 #3
    I thought that there was some

    I thought that there was some connection with Raspberries and overall health - my main downside with Raspberries is that they cost more than most other kinds of berries - usually substantially more. I try to pick them up on sale.

  • SandiaBuddy
    SandiaBuddy Member Posts: 1,381 Member
    #4
    More on red berries

    https://www.nature.com/articles/s41598-018-22388-5

    The most potent SIRT6 activator, cyanidin, belonged to anthocyanidins, and produced a 55-fold increase in SIRT6 activity compared to the 3–10 fold increase for the others. Cyanidin also significantly increased SIRT6 expression in Caco-2 cells. 

    * * *

    Interestingly, the most prominent activators for SIRT6 among the flavonoids were the anthocyanidins, the universal plant pigment, responsible for the red, purple, and blue color in many fruits, vegetables and flowers. The most potent compound in the class of anthocyanidins, cyanidin, significantly increased the deacetylation activity of SIRT6. It is most abundant in red berries including bilberry, raspberry and cranberry. Studies have suggested that anthocyanidins, including cyanidin, may play important roles in helping to reduce the risk of many age-related diseases. The effect has been linked to their protective effect against oxidative stress, which results in the decreased production of ROS and nitrogen species28,29,30. Cell culture and in vivo studies of anthocyanidins and their glycosylated counterparts (anthocyanins) revealed anticarcinogenic properties against colon, skin, and lung cancer. While laboratory studies have provided some insight into how anthocyanins may work, the exact mechanism for how these compounds prevent cancer is unclear.

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