Confused by lab results
I decided to get a PSA test as my uncle passed away from PC at the age of 68 this year. I am only 44 but for the last 10 years I have noticed that in the mornings my urine stream is not as robust as it used to be.
My total PSA came back at 2.3 but my total free PSA percentage is 17%
My family doctor did not seem concerned.
I thought that if the free PSA % is low that is a cause for concern? And that I am at the high end of the scale for normal total PSA as well .
Does anyone have any insight on this?
THanks! Don
Comments
-
You do well in being vigilant
Don,
Welcome to the board. In my opinion you are right in doing the tests and being concerned with the results. Your uncle's PCa experience places you at higher risk (2x) to contract the disease. If your dad has it then the risk is higher at 4x.
It is not common to have urination issues/symptoms due to prostate cancer (PCa) unless this is in a very advanced status. Urination retention or urge is many times associated to hyperplasia or infection/inflammation. These conditions have nothing to do with cancer and can increase the PSA value. Other factors that can increase the PSA is sex or riding a bike (or tractor, etc) the day before drawing blood for the test. The free PSA at 17% is on the border line but the total PSA used in the calculations can be a faked value if hyperplasia or any other aspect was involved in the result.
In your shoes I would try checking the issue starting with a protocol of antibiotics/anti-inflammatory dugs taken during three weeks and follow with a PSA test one month later. A biopsy is the ultimate means to diagnose cancer. It is invasive so that you can try also testing other biomarkers proper to idetify PCa, such as;
PCa3 (genetic analysis of cells in the urine)
PAP (prostatic acid phosphatase)
CEA (Carcinoembryonic Antigen)
NSE (Neuron Specific Enolase)
CGA (Chromogranin A)
PHI (Prostate Health Index–pro-2PSA)I hope that cancer is not the issue but you need to be vigilant.
Best wishes.
VGama
0 -
Hey VGama ,VascodaGama said:You do well in being vigilant
Don,
Welcome to the board. In my opinion you are right in doing the tests and being concerned with the results. Your uncle's PCa experience places you at higher risk (2x) to contract the disease. If your dad has it then the risk is higher at 4x.
It is not common to have urination issues/symptoms due to prostate cancer (PCa) unless this is in a very advanced status. Urination retention or urge is many times associated to hyperplasia or infection/inflammation. These conditions have nothing to do with cancer and can increase the PSA value. Other factors that can increase the PSA is sex or riding a bike (or tractor, etc) the day before drawing blood for the test. The free PSA at 17% is on the border line but the total PSA used in the calculations can be a faked value if hyperplasia or any other aspect was involved in the result.
In your shoes I would try checking the issue starting with a protocol of antibiotics/anti-inflammatory dugs taken during three weeks and follow with a PSA test one month later. A biopsy is the ultimate means to diagnose cancer. It is invasive so that you can try also testing other biomarkers proper to idetify PCa, such as;
PCa3 (genetic analysis of cells in the urine)
PAP (prostatic acid phosphatase)
CEA (Carcinoembryonic Antigen)
NSE (Neuron Specific Enolase)
CGA (Chromogranin A)
PHI (Prostate Health Index–pro-2PSA)I hope that cancer is not the issue but you need to be vigilant.
Best wishes.
VGama
Hey VGama ,
Thanks so much for the reply.
So are you saying the free PSA % can be thrown off by an elevated total PSA for some benign reason? Thanks again. I will be vigilant!
0
Discussion Boards
- All Discussion Boards
- 6 CSN Information
- 6 Welcome to CSN
- 121.9K Cancer specific
- 2.8K Anal Cancer
- 446 Bladder Cancer
- 309 Bone Cancers
- 1.6K Brain Cancer
- 28.5K Breast Cancer
- 398 Childhood Cancers
- 27.9K Colorectal Cancer
- 4.6K Esophageal Cancer
- 1.2K Gynecological Cancers (other than ovarian and uterine)
- 13K Head and Neck Cancer
- 6.4K Kidney Cancer
- 671 Leukemia
- 794 Liver Cancer
- 4.1K Lung Cancer
- 5.1K Lymphoma (Hodgkin and Non-Hodgkin)
- 237 Multiple Myeloma
- 7.1K Ovarian Cancer
- 63 Pancreatic Cancer
- 487 Peritoneal Cancer
- 5.5K Prostate Cancer
- 1.2K Rare and Other Cancers
- 540 Sarcoma
- 734 Skin Cancer
- 653 Stomach Cancer
- 191 Testicular Cancer
- 1.5K Thyroid Cancer
- 5.9K Uterine/Endometrial Cancer
- 6.3K Lifestyle Discussion Boards