Blood clot in heart after chemo

I will be 6 weeks out of R EPOCH this sunday, I had an Eco Cardio Gram on August 21 due to heart pain after my picc line was removed and they found a mass they think is a blood clot. They started me on Lovenox shots right away. I met with the cardiologist and he is sending me for an MRI. 

I met with my Oncologist yesterday and she said this happens to 10% of folks after chemo. Has this happened to anyone before? I'd be lying if I said I wasnt nervous especially after what I just went through the past 5 months. 



  • Max Former Hodgkins Stage 3
    Max Former Hodgkins Stage 3 Member Posts: 3,797 Member

    Never heard of chemo causing a blood clot, Jacqui, ever.  No one here is a medical authority, but never heard of it. Also, it is not listed as a common or an uncommon side effect on any of the drugs in R-ABVD or R-Chop. I will check EPOCH when I finish here. Some chemos do occasionally cause heart damage, like Adriamycin (nicknamed "Red Devil"), but that usually shows long after treatment ends, and mimics congestive heart failure, not blood clots.  Regardless, of course, we wish you wellness and a quick resolution of this odd occurrence.


    I checked all listed side effects of all of the meds in EPOCH at , and none of them mention blood clots at all. Rituxan can very rarely cause irregular heartbeat, but of course irregular heartbeat is unrelated to blood clots anyway. is  a very highly regarded source for chemotherapy information.  I would ask your doctor for clarification regarding her "10%" comment.

    Here is the link to R-EPOCH:

    You can go to the article on each individual drug and review known side-effects by clicking the blue LEARN MORE box



  • yesyes2
    yesyes2 Member Posts: 591
    Blood Clot in heart

    Hi Jacquil,

    I was wondering if the blood clot could have been a side effect/result of your PICC line?  I have had a port in my chest since I did RCHOP in 2009/10.  I know with ports, especially ones that go over the clavical, that blood clots are a concern.  Why not a PICC line. Worth asking your Oncologist about this and the 10%.

    Good luck to you.  Please let us know what you find out.

    Best to you,