Votrient side effects how lng do they last?

Been 2 years for me. White hair first diarrhea quite often. Taking Diphenoxylate for that. Also taking Pantoprazole for upset stomach issues. For the most part the worst is the diarrhea. Wiped my backside more in the past 2 years than my entire life to date I am 55 years old. Been on 800mg for the 2 years. First 8 months I stopped 4 times for 3-4 days each time. Appetite went down the tubes. The rest re set my system. For some reason beef seems to intensify the diarrhea. Liver functions are all good. Everything continues to shrink or remain stable. Good luck. I went through IL2 as well. First round was a breeze. Round 2 almost did me in. Thank god that is over. Wasn’t the home run that we wanted more like a solid double. Good luck.

Time2Luv You may not like the suggestion I am going to give but I would run it by your oncologist. Do not cancel your dream trip to Alaska. I am guessing that your vacation is no more than two weeks long. I would suggest that you either reduce your dosage or outright stop taking Votrient for the duration of your vacation - once your vacation is over resume your full dosage. Once again, this is only a suggestion - but believe me I have been there. I was on 800 mg Votrent for almost 2 ½ years. At times the diarrhea was really bad and nothing seemed to help. I lived in a very paranoid state of “Where the nearest bathroom” I carried TP in my car at all times and believe me I christened many a vacant lot and wooded space on the side of a highway. Sorry, if I am getting a little graphic here. For me, it got to point that for very special family events and vacations it was not worth it too constantly worry about this side effect. To do so would be to become a prisoner of the drug and to never leave my house. I caution you that I did this VERY sparingly no more than 3-5 times a year and for short periods of time. While I was on Votrient I had dental and hernia repair surgery and was ordered by my oncologist to stop taking Votrient 3 days prior to surgery. So you can see going off of it for a short period of time is no big deal. Going off of Votrient for more than 15 days could start affecting its potency.

Once again this is only a suggestion. I am sure many members of CSN are going to rime me out for making it but talk to your oncologist. Enjoy your vacation - BDS      

Ed Brabant said:

Votrient

Been 2 years for me. White hair first diarrhea quite often. Taking Diphenoxylate for that. Also taking Pantoprazole for upset stomach issues. For the most part the worst is the diarrhea. Wiped my backside more in the past 2 years than my entire life to date I am 55 years old. Been on 800mg for the 2 years. First 8 months I stopped 4 times for 3-4 days each time. Appetite went down the tubes. The rest re set my system. For some reason beef seems to intensify the diarrhea. Liver functions are all good. Everything continues to shrink or remain stable. Good luck. I went through IL2 as well. First round was a breeze. Round 2 almost did me in. Thank god that is over. Wasn’t the home run that we wanted more like a solid double. Good luck.

Please tell me how the Pantoprazole worked, My husband is so sick from the Votrient.  is it over the counter or prescription.  getting very scared. he is never sick and this is kicking his back side. If anyone has any advise for me, please let me know

Ed Brabant said:

Votrient

Been 2 years for me. White hair first diarrhea quite often. Taking Diphenoxylate for that. Also taking Pantoprazole for upset stomach issues. For the most part the worst is the diarrhea. Wiped my backside more in the past 2 years than my entire life to date I am 55 years old. Been on 800mg for the 2 years. First 8 months I stopped 4 times for 3-4 days each time. Appetite went down the tubes. The rest re set my system. For some reason beef seems to intensify the diarrhea. Liver functions are all good. Everything continues to shrink or remain stable. Good luck. I went through IL2 as well. First round was a breeze. Round 2 almost did me in. Thank god that is over. Wasn’t the home run that we wanted more like a solid double. Good luck.

I have been taking Votrient for RCC - clear cell for a year and a half.  Main side effects for me have been white hair, diarrhea, lethargy, and now I have geographic tongue.  I want to put memory loss on the list, but my wife is not so sure that Votrient is the cause.  I have gone on an elimination diet to see if there are any foods I can tolerate and have found that  Rice, Chicken, Pork, Fish, Apples, Bananas, milk, and cheese are about all I can really tolerate well.  I can eat occasional tapioca and home made ice cream.  I take Lomotil and Zofran to control the occasional bout of diarrhea and nausea or stomach pain.  My oncologist started me on 800 mg. of votrient, but now it has been reduced to 600 mg.  I am still getting good results and am able to tolerate the medication a little better.

Time2luv said:

update

Started Votrient on a Thursday, BP went high on 4th day. 5th day High BP and vomiting. They took me off it for 2 days, added another BP and nausea pill. BP down. Started again at 400mg instead of the 800mg. See oncologist in a week to discuss changes. Tired expecially in morning and evening. Doing pretty good.

Sorry to hear about the reaction to Votrient.  I was already on BP medication before I started and noticed no difference.  I have really narrowed down what foods I can eat without causing diahrea regularly.  I occasionally take Zofran for nausea and Lomotil for diahrea.  But I have found that the best thing for me is to avoid fruits and vegetables, except apples and bananas, and avoid gluten and most spices.  Tiredness goes with the territory and I take a nap almost every day after work.  Then go to bed early.  I'm at 600 mg.