1st Recurrence

3750lsd, I am sorry I cannot help you with an answer Carbo/Doxil, but I think if you "Search" for Doxil there is one if not more discussions on it.  I know I have seen it, and if you don't see it here you might want to "Search" in the Uterine board.  I can't remember where I saw it (must be that darn chemo-brain)

My story isn't exactly like yours...I have been in constant treatment for nearly 3 years.  I had the typical first-line treatment and debulking, followed by IV/IP chemo, then a year of monthly taxol.  Then gemzar, a dose or two of avastin, followed by doxil and now topetecan. 

My hair had a hard time growing with the taxol, but after that, the other drugs didin't seem to bother my hair. 

The only drug that gave me problems was doxil.  I had a horrible, horrible reaction after the second dose.  Extremely painful blisters over hands, feet, mouth and throat, any where skin touches skin (Yes, EVERYWHERE skin touches skin!)  I was in very bad shape and in a wheelchair for three weeks.  I don't mean to scare you because I know my reaction was extreme and not the typical at all.  I would suggest you take seriously all the warnings about avoiding heat and especially avoiding anything that causes friction on the skin.  Like holding the handles of a bicycle.  Or, carrying a suitcase.  Really, just be very, very careful...pamper yourself...don't do anything!  Really, just tell people, you know, I have to really not risk my hands or my skin.

I am so sorry you have the disappointment of a recurrence, but you smacked it down before and I am sure you will do it again!  Sending you all my best wishes.

I can't really comment on your particular cocktail; I was diagnosed stage IV ovar in Feb. 2006. Besides the surgery , debulking, etc. I had 6 mo. of carbo & cispl, then 6 mo. cispl. & gemzar. I didnt experience much problem with the gemzar. Recurrence, which was expected "at some time" wasn't until May of 2014.....I had weekly cocktails of cispl. & taxol for 5 months and am now NED  The taxol was pretty hard on me, had a couple of tranfusions and iron treatments, and neuropathy at the end. I am happy to say the neuropathy is S L O W L Y getting better.........I am just now FINALLY having some really good days.....guess I am just impatient since everyone was getting excited about the last chemo (0CTOBER 20!), so I thought I should feel better sooner. What has gotten me thru this, besides having a supportive hubby (except when he is overwhelmed, which is expected) is that I made my OWN schedule: if I knew it was going to be a really crappy day, I would announce I was spending the day on the couch being useless and probably sleeping. I didn't try to act like I was having a wonderful time. That was so much easier on me, as the patient, and also hubby, the caregiver, knew it was a day for him hang out with buddies or roam around Home Depot. Take care of yourself........I wish you the least problem free chemo possible...........