Interesting Article in Time Magazine: "Sabotage - Why Cancer Vaccines Don't Work"

Especially since I have read dozens and dozens of vaccine trials and never saw IFA used as an adjuvant, personally I would speculate the reason of poor success is the state of the patients going for clinical trials, usually heavilly pre-treated with no immune sysytem left and huge tumours. Also I haven't seen a single trial that used chemo to deplete T-reg and MDSC's first (the immune supressive cells)

Many reasons why a vaccine is so hard to develop, but mother nature will be beat, ask her about TB, Polio, Smallpox etc...

manwithnoname said:

interesting

Especially since I have read dozens and dozens of vaccine trials and never saw IFA used as an adjuvant, personally I would speculate the reason of poor success is the state of the patients going for clinical trials, usually heavilly pre-treated with no immune sysytem left and huge tumours. Also I haven't seen a single trial that used chemo to deplete T-reg and MDSC's first (the immune supressive cells)

Many reasons why a vaccine is so hard to develop, but mother nature will be beat, ask her about TB, Polio, Smallpox etc...

The above is likely correct.  Vaccines require a functional immune system to work, as they work indirectly through the body's immune system (unlike chemo which has a direct effect on the tumor cells).  You can't run vaccine trials on patients with non-functional immune systems, you need to run them as first-line treatments.  Problem is, that is not the way our clinical trials are set-up here in the US.  Normally (with a small molecule that works directly against the cancer), you test in terminal patients that have failed all other standard options, but that approach won't work with vaccines.  There are a myriad of other potential reasons some vaccines don't work, or don't work on a high enough percentage of people, but every vaccine trial should require a functioning immune system as a prerequisite for admittance to the trial. Also, we need to understand that even if a vaccine only works on a low percentage of people, it still has tremendous value to those it will help.  I read a report on a trial they did at Stanford with a leukemis vaccine, and 2/6 patients went into complete remission with just vaccine treatment, but 2/3rds had no response.  That would normally be a bad result for a drug, but IMHO that was a hell of a good result for those 2 people.  What we need to do is understand why it worked for 2/6 but not the other 4, instead of giving up on the comcept.

Tedd

tanstaafl said:

PSK, CIM

 PSK and cimetidine modulate dendritic cells, here and now, for about $10/month and $75/month, respectively.

only joking of course, love those mushrppms, just had some ahcc, might do a psk mouth wash before my enemas tonight.

sorry friends away from the net enjoying life. thats the things we have left after the cancer. this what everyones told me to do over the years. especially winter, and you see I do listen. mind you still doing all the supplements and alternatives but having lots and lots of fun. indulgence is healthy, I have got two massages booked for torrow.

Oh, I am up at duderstadt, they sucked out the blood for the 3rd vaccine this morning. 

I am glad my tumours appear to have been gone, shiit if they could read, they might mount a regard action and try and kill me again if they read that report.

I feel great, so with the greatest repsect, I think the article is a piece of dog poo. well worth discussing though, because it clearly explains how scientific arguments can confound the real clinical achievement issues.

Craig, thankyou sincerely, think abut the smoke screen friends, this article is the ultimate con. look it may make some valid points, but i have binned it.

I would not even waste doc N time on this, he is presenting his sucessful trial results at asco, you got to be invited, not everyones doc presents at asco. does yours ?.

I must be a sucker, I am hooked, hook line and sinker. I have faith in what I have researched and what I have experienced.

did you see the other post, I have cut all chemo out, even the micro scopic targetted stuff builds resistance. saving chemo for the very very very end, hopefully never needed.

gambling everything on the immune system. this makes my life exciting and survival a bit sweeter. if I loose, well we all going to die, but I am going to have some serious fun along the way. its an open invitation, join me, you might enjoy it also.

why build resistant tumours which makes the immune systems job harder.

did a blod test today which says I am HIV positive, go figure, I have nt had sex for way to long, and now possibly HIV. Its likely an artifact in the prevaccine blood tests.

they have these false positives before, they never result in a confirmed positive, bit it knocked me sox off for a while.

my focus is exercise, qigong, enemas, enjoying LIFE, my research and learning german and getting ready for these really interesting conferences I am attending.

I love everyone here, you know that, but the single best thing I can do for the immunotherapy revolution is stay alive.

whats more important 20 minutes on csn or 20 minutes on a treadmill getting your 15 mets ? as much as I love you all, its exercise. you can subsistitute sauna for exercise.

I had dinner tonight with lorraine, she might be my first survivor interview on the immunotherapy channel. all her GBM brain tumours have disappeared, her onc cannot explain it. We dinner with her grateful husband. we toasted doc N. I won't tell Lorraine about the article, she is so happy, she has outlived her prognosis. she is like an amazing grandmother. If we do an interview, I will invite you to the formal launch of the immunotherapy channel with the worlds my wonderful hopeful stories.

We all can believe and do what we want, thats whats beautiful about free will and freedom of the press. the tradegy is that people will read the article and be negative on immunotherapy. thats life the carnage continues, I cannot help that, or you my friends. We can each just run our own race and try to live it joyfully.

did you hear about big pharma trying to charge 6K for a small antigen used to make these vaccines ? so the price doubles from 6K to 12K.

the conspiracy theories are all trivial re health and big pharma, whats serious is the blantant profiteering and capitalistic process we are all complicit in supporting. 

Can you see it, so chemo's profits will dimish, they are positiining themselves to profit on the next medical innovation wave. And the other day I heard of 

successful cancer anitbodies like removab being purchased by big pharma and going nowhere. takeout the competitive products and keep profits maximised. I think we need to change the the system friends. I cannot do it on my own, but I think its time we put it on the agenda. if not us, than who ?

some trivia, the three courses of removab over the last 2 weeks cost 600USD each. so 1800USD was the drug cost associated with the main component of my successful treatment.

I am asking doc N if I can be the first to have gamma delta cells direct injected into the remmants of my peritoneal mets and liver. I will video it, should make real interesting video. to risk your life in the pursuit of saving it, now that has so much appeal to me. consider this, I now have no visible mets, I possibly have more to loose, but I am disposed to take the riskier, path least travelled.

hugs,

Pete

sdp said:

For Peter tray and his german Docs
This article is interesting and would be apt for Peter tray to ask his german Docs and see what their response is.

If he is going to take further vaccines and if the Docs try to assimilate the knowledge from this article it may just hasten the process and maybe we all can benefit from the result as it would cut quite a long waiting period.

More of us with the resilience And the resources that Peter has going for him could try the same and we can probably be nearer to some sort of treatment in a much lesser time frame.

Hope Peter reads this and gets going after the german Docs and it all turns out for the better for him and all of us.

If I get a response i will put it here.

hugs,

Pete