gambling on immune system said no more chemo embolisations

ccfighter said:

Pete,
Have you considered HPV

Pete,

Have you considered HPV vaccine therapies since you tumor has an HPV link?  Im jumping over from the gyn boards and was diagnosed with cervical cancer in 2011 stage 2A though am now recurrent and metastatic.  I have spent a lot of time researching vaccine and immune therapy for my particular cancer which is 99.7% of the time HPV positive.  All HPV associated malignancies express E6 and E7 protein which provides a target for vaccines.  So far some decent success in the ADXS11-001 vaccine and INOVIO has one that is reversing high grade precancerous lesions.  Both still in clinical trials, but have heard that preliminary data from the phase II trial of ADXS11-001 is great enough to move to phase III probably in 2014.  Considering you HPV status, this may be of use to you.

Dear Friends,

 

Kim, thanks, thats sweet.

Tedd, You can stay with me for free in the apartment 300 meters from the clinic, that will save a few thousand.

 

So now each day, the therapy plan changes, and yes different perspectives between treating specialisists. The reply to the email i sent this morning was, you better come and have those mirco mets chemo and embolised.

 

Some clear benefits in the strategy, controlling existing micro mets in areas of residual disease, leaving the immune system to handle any of mets popping up anywhere else. Also remember the claimed benefits of localised avaistin and the immune system, still experimental and an documented benefit.

 

Leaving money out of the decisions, and I have always just said whats clinically prudent, irrelevant of the funds, I get a feeling that getting the localised, embolised, targetted chemo the safest most conservative route.

 

So one moment, one direction, next moment next direction. I will discuss Vogel preference with Kopic, I will discuss it with Nesselhut.

 

I have no choice but to love the clinical difference of opinion between these wonderful doctors. Its my choice, its likely will be the most conservative but i will take in all the opinions.

 

hugs,

Pete

 

PS My emails to these doctors are concise and to the point, they won't read through all my BS like you guys,

 

 

Dear Prof,

 

I just wanted to make sure that todays appointment was postponed.

I am down at hallwang and have just gotten over my second removab treatment.

 

I am heading up to duderstadt to do my next vaccine shot with doctor nesselhut.

 

Is it possible to just get an mri, so you can confirm the cancer is not active. 

 

As i have no manifest disease at present, I was considering deferring the embolisation. I will leave you to discuss this with Dr Asir Kopic.

 

I am very grateful for your care, but hope i am well enough not to see you professionally. That said is having the liver and the peritoneum treated periodically in a preventitive way ever been considered ?

 

Your adice about reducing the likelihood of recurrence sincerely appreciated. 

 

cheers

ccfighter said:

Pete,
Have you considered HPV

Pete,

Have you considered HPV vaccine therapies since you tumor has an HPV link?  Im jumping over from the gyn boards and was diagnosed with cervical cancer in 2011 stage 2A though am now recurrent and metastatic.  I have spent a lot of time researching vaccine and immune therapy for my particular cancer which is 99.7% of the time HPV positive.  All HPV associated malignancies express E6 and E7 protein which provides a target for vaccines.  So far some decent success in the ADXS11-001 vaccine and INOVIO has one that is reversing high grade precancerous lesions.  Both still in clinical trials, but have heard that preliminary data from the phase II trial of ADXS11-001 is great enough to move to phase III probably in 2014.  Considering you HPV status, this may be of use to you.

i will ask doc nesselhut, vaccine guru what he believes re e6 and e7 for my clinical manage.

your comments awesome and informative, the likely of hpv 18 /16 and colorectal almost as certain as cervical. a big piece of the cancer jigsaw got a whole lot clearer. if you cervical gals can have a vaccine, maybe our colorectal kids can also. maybe even a vaccine for us adults.

clinically i can see vaccines being developed to knockout tumour cells and virus cells simultaneously. 

dual purpose vaccines, using ranges of immune cells.

hugs,

pete

Borac said:

Pete, I am new to this board
Pete, I am new to this board but can you please explain where and what kind of treatment you are getting? Did you have regular chemo and surgery? Is this alternative type of treatment? Did you have mets? Where? Thank you so much and good luck

just google pete media release hallwang

its crazy how easy it is to find my mess blog. just search for the media release around mid jan this year. the german medical report has a complete summary of therapies.

re  Is this alternative type of treatment? not in my books, it was the only therapy i knew that suggested curative potential, so as i love life, do not want to die, i jumped on the plane with high hopes and no expectations and a few bucks on the mastercard. alas its all in blog and here.

hugs,

pete

smokeyjoe said:

Pete, I'm not quite

Pete, I'm not quite understanding repeatedly getting shots of chemo. and/or avastin into tumors.  Could something in your lung or liver  have been dealt with by radiofrequency ablation (I'm not sure of spelling)  in a shorter course of time??  I figure you can't have radiofrequency to the peritoneum,  and these shots probably work on those well.     Just asking, as I think it's Phil who gets radiofrequency ablation for his lung mets, and it seems to be successful for him. 

the regular local embolisations and the other therapies were just the prefered approach recommended by the hallwang doctors.

my sydney hipec surgeon, offered rfa for the lung met. but as i avoided the hipec and I hope the lung thingy is sorted. argument if its cancerous or not. the pet said it was treated disease.

i know about phils treatment success, what's helped him, was not offered to me. the peritoneal spread the key difference and the immunotherapy route offering the only curative option. rfa to the peritoneum not possible to my understanding.

as i love scuba diving, i also was nervous about burning a 1 centimeter spot in my lung. hopefully my immune system can just eat the tumour and i can go diving again with really healthy lungs. of course if these therapies fail, i still have phils types of therapies available. but phil is on chemo, i am seeking to avoid chemo, have maximum quality and quantity of life. trying to turn this stage 4 illness into a managable chronic illness, i don't know if its possible to get the ctc's down to zero and the stem cell risk reduced. 

so many potentially useful therapies to help me stay NED, these types of vaccines mentioned by ccfighter just fantastic.

seeing the possible root cause being hpv 16/18 and now effectively a possible curative option coming from the cervical board. how nice to have friends in the CC space. this is a clear advantage of csn having such a board spectrum of cancers, with a few pioneering souls sharing the lastest therapies.

i want to get off avastin and chemo asap. i am testing the strength of my immune system day by day now. going to fortnightly cea's and praying.

hugs,

pete