How much does stress contribute to the onset of cancer?

2

Comments

  • manwithnoname
    manwithnoname Member Posts: 402

    I found this article (abstract only)...

    which suggests that stress causes physical damage to our DNA, actually making the telomeres (nucleotides that cap our chromosomes, and protect them from decay) shorter.

    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC534658/?rendertype=abstract

    title-

    Accelerated telomere shortening in response to life stress

    Not sure how to make that link clickable...

    Weird

    i posted a link a while back that shows increased stress is better for breast cancer survival, and increased telomere length means more agressive cancer doesn't it? too late here but will look into this...

  • lilacbrroller
    lilacbrroller Member Posts: 412 Member

    Weird

    i posted a link a while back that shows increased stress is better for breast cancer survival, and increased telomere length means more agressive cancer doesn't it? too late here but will look into this...

    stress

    I don't know. I have a real knee jerk "No" reaction to anything that says or implies that getting cancer is someone's own fault.  Citing stress as a cause kind of creeps over to that side.. I've read articles about "the cancer personality" which claims that being a nice accomodating, self correcting person makes one more likely to be afflicted (I don't think Steve Jobs or Hugo Chavez would fall into this category.)  I definitely believe genetics is a strong driver, and environmental factors to which we are genetically succeptble.  Stress?  I"m researching immunotherapy and want to know more about how our own immune system should be attacking the tumors and associated cancer cells. Maybe there is a connection, if stress reduces our immune response. 

    I was diagnosed in June and was actually pretty content. Had a lot of stress in my 20s, but at 46 am beyond that now. No stress near to what some of you have been going through - yikes!  I would say you all are pretty hardy folks, to deal with everything you mentioned and cancer. Wow!

     

    Still reading!  Let me know what you find out. I will too.

    Karin

  • pete43lost_at_sea
    pete43lost_at_sea Member Posts: 3,900 Member

    I found this article (abstract only)...

    which suggests that stress causes physical damage to our DNA, actually making the telomeres (nucleotides that cap our chromosomes, and protect them from decay) shorter.

    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC534658/?rendertype=abstract

    title-

    Accelerated telomere shortening in response to life stress

    Not sure how to make that link clickable...

    the science

    a one two punch, i made self directed change based on science like this everyday lmost in the journey.

    its scary how much contrl and responsibility we have over our health and environment. thats why holistic medicine is so unpopular, its not people don't believe it that in itse;f we are called to make big changes. ie loose weight, loose wives to save lives. alas survival in our society is hardwork, cancer show this so clearly.

    thanks for the study, evidence based life style is the only way to go, its like evidence based medicine. so ironic. just opinions. the last thing we want any friends here is feeling guilt or stress. relax and enjoy your days, 

    my tip

    next time something or someone gets you really upset, just think to your self about your life, your survival and smile and laugh. they cannot touch your heart and peace of mind if you let them.

    my father in law, told me i was a useless peice of shite, that the 120,000K on german treatments a waste, that i was no good at all, he is 84 and almost dead.

    its was the most disappointing things i had heard, this was in front of my mum and who was visiting. even in front of my kids. i was rattled, i did not argue back, i was respectful, said well your entitled to your opinion. we started to discussion about what would happen after he passed to his old and very ill ( mentally)) wife. he said the way i wasted money i would never be allowed to put a foot inside his house. it was hurtful. so the old mother in law is off to old peoples home at some point soon. we could not care for her, well my wife could not cope anyway.

    that the beauty of life, always bringing us chsallenges, when we least expect it.

    my reaction is all we control, my cortisol levels are so good, i will keeep them low. my success so far is now like a massive snowball, i know holistic works, i actually felt it while doing qigong. 

    Ann go bak to qigong dearest, it might save your butt, but really do the shite, do it properly with an intensity. i will do an hour in the bathroom, like i did in the black forest.

    dont just go to classes, like me, daily practice is the key,, do it at home everyday, thats my challenge, the net, csn or qigong. qigong wins each time, it shoukld but it does not.

    qigong is the ultimate anti stress tool, you got it already, maybe the meds will not be necessary. they screw your brain. ok lots of brain hormones upset with meds, ie dhea, cortisol. short term may help, longer term maybe harmful. as always ask your doctor and oncologistic. its good to get opinions.

    I did my brain hormone profile, it was worth the $170 euro.

    watch the video "the marketing of madness", its confronting , it maybe sensational , if 5% of it is true , it scary, more than 5% and its tragic.

  • pete43lost_at_sea
    pete43lost_at_sea Member Posts: 3,900 Member

    stress

    I don't know. I have a real knee jerk "No" reaction to anything that says or implies that getting cancer is someone's own fault.  Citing stress as a cause kind of creeps over to that side.. I've read articles about "the cancer personality" which claims that being a nice accomodating, self correcting person makes one more likely to be afflicted (I don't think Steve Jobs or Hugo Chavez would fall into this category.)  I definitely believe genetics is a strong driver, and environmental factors to which we are genetically succeptble.  Stress?  I"m researching immunotherapy and want to know more about how our own immune system should be attacking the tumors and associated cancer cells. Maybe there is a connection, if stress reduces our immune response. 

    I was diagnosed in June and was actually pretty content. Had a lot of stress in my 20s, but at 46 am beyond that now. No stress near to what some of you have been going through - yikes!  I would say you all are pretty hardy folks, to deal with everything you mentioned and cancer. Wow!

     

    Still reading!  Let me know what you find out. I will too.

    Karin

    the immunotherapy i am having cost $10,000 K

    for 17 million trained cells, get another hit in 3 weeks. this medicine is the future. see my blog.

    its here now, don't wait as it cannot handle large tumour burdens.

    the stress response was the first factor i asked about in my after vaccine therapy.

    doc N said its important, he could not say to what exent. but his statement helped me, keep peace of mind as my number one therapy goal.

    i accept i was responsible for my health before cancer, my life style contributed to it. now my life style contributes to my remission. just my opinion,  i respect your view, its different to mine and felt the same way earlier when i was 137kg. 

    hugs,

    Pete

     

    ps this is a great post

  • annalexandria
    annalexandria Member Posts: 2,571 Member

    stress

    I don't know. I have a real knee jerk "No" reaction to anything that says or implies that getting cancer is someone's own fault.  Citing stress as a cause kind of creeps over to that side.. I've read articles about "the cancer personality" which claims that being a nice accomodating, self correcting person makes one more likely to be afflicted (I don't think Steve Jobs or Hugo Chavez would fall into this category.)  I definitely believe genetics is a strong driver, and environmental factors to which we are genetically succeptble.  Stress?  I"m researching immunotherapy and want to know more about how our own immune system should be attacking the tumors and associated cancer cells. Maybe there is a connection, if stress reduces our immune response. 

    I was diagnosed in June and was actually pretty content. Had a lot of stress in my 20s, but at 46 am beyond that now. No stress near to what some of you have been going through - yikes!  I would say you all are pretty hardy folks, to deal with everything you mentioned and cancer. Wow!

     

    Still reading!  Let me know what you find out. I will too.

    Karin

    I definitely don't subscribe...

    to the whole "just have a positive attitude and you won't get cancer" kind of thinking.  Personally I'm a very optimistic, happy person...even when I was under tons of stress I never felt especially unhappy.  I was always able to see the positive side of things.  But what I'm getting at is more the physiological impact of stress, regardless of attitude.  That article I linked to mentions that caregivers of people with long-term illnesses lose something like 5 years of life to DNA damage, which they are assuming is caused by stress.  I think this isomething that happens to all of us, regardless of attitude.  But you're right that there are also many other factors involved in the onset of cancer...stress is just one many.  AA

  • coloCan
    coloCan Member Posts: 1,944 Member

    the science

    a one two punch, i made self directed change based on science like this everyday lmost in the journey.

    its scary how much contrl and responsibility we have over our health and environment. thats why holistic medicine is so unpopular, its not people don't believe it that in itse;f we are called to make big changes. ie loose weight, loose wives to save lives. alas survival in our society is hardwork, cancer show this so clearly.

    thanks for the study, evidence based life style is the only way to go, its like evidence based medicine. so ironic. just opinions. the last thing we want any friends here is feeling guilt or stress. relax and enjoy your days, 

    my tip

    next time something or someone gets you really upset, just think to your self about your life, your survival and smile and laugh. they cannot touch your heart and peace of mind if you let them.

    my father in law, told me i was a useless peice of shite, that the 120,000K on german treatments a waste, that i was no good at all, he is 84 and almost dead.

    its was the most disappointing things i had heard, this was in front of my mum and who was visiting. even in front of my kids. i was rattled, i did not argue back, i was respectful, said well your entitled to your opinion. we started to discussion about what would happen after he passed to his old and very ill ( mentally)) wife. he said the way i wasted money i would never be allowed to put a foot inside his house. it was hurtful. so the old mother in law is off to old peoples home at some point soon. we could not care for her, well my wife could not cope anyway.

    that the beauty of life, always bringing us chsallenges, when we least expect it.

    my reaction is all we control, my cortisol levels are so good, i will keeep them low. my success so far is now like a massive snowball, i know holistic works, i actually felt it while doing qigong. 

    Ann go bak to qigong dearest, it might save your butt, but really do the shite, do it properly with an intensity. i will do an hour in the bathroom, like i did in the black forest.

    dont just go to classes, like me, daily practice is the key,, do it at home everyday, thats my challenge, the net, csn or qigong. qigong wins each time, it shoukld but it does not.

    qigong is the ultimate anti stress tool, you got it already, maybe the meds will not be necessary. they screw your brain. ok lots of brain hormones upset with meds, ie dhea, cortisol. short term may help, longer term maybe harmful. as always ask your doctor and oncologistic. its good to get opinions.

    I did my brain hormone profile, it was worth the $170 euro.

    watch the video "the marketing of madness", its confronting , it maybe sensational , if 5% of it is true , it scary, more than 5% and its tragic.

    Does the following count as an example?

    http:/medicalxpress.com/news/2013-01-loneliness-chronic-stress-taxes-immune.html

     

    if inflammation is considered as a form of stress, that can contribute to cancer as well

     

  • annalexandria
    annalexandria Member Posts: 2,571 Member
    coloCan said:

    Does the following count as an example?

    http:/medicalxpress.com/news/2013-01-loneliness-chronic-stress-taxes-immune.html

     

    if inflammation is considered as a form of stress, that can contribute to cancer as well

     

    Yes, I think that does count!

    It's kind of fascinating how many things can affect our health, not just the obvious things like exercise and diet.  Hopefully, this board helps to alleviate the loneliness of having cancer that no doubt many of us feel.

  • manwithnoname
    manwithnoname Member Posts: 402
    coloCan said:

    Does the following count as an example?

    http:/medicalxpress.com/news/2013-01-loneliness-chronic-stress-taxes-immune.html

     

    if inflammation is considered as a form of stress, that can contribute to cancer as well

     

    Facinating

    Very relavant for me, cytomegalovirus is found in 100% of Gioblastoma brain tumors, none is found in healthy brain tissue, there are even trials targeting this virus in anti-cancer. 

    No one is sure exactly what there part is in cancer but they do alter the tumor microenviroment, and most people have this virus.

    JC virus and SV40 are also found in tumor samples.

    Il-6, TNF alpha , IL-1 beta are all target pathways for cancer.

    I think Malcolm Gladwell wrote about a community/town in the US that has virtually no heart disease, they are very social.

     

  • annalexandria
    annalexandria Member Posts: 2,571 Member
    In his book "Outliers"...

    it was the town Roseta, PA.  He decided that it was the social and communal nature of life in that town that led to the low rates of heart disease (although basically the whole town was populated by people who descended from one family in Italy, so I'm not sure if there's any way to disentangle the role of genetics from that of enivronment in this particular case).

  • YoVita
    YoVita Member Posts: 590 Member
    Great thoughtful topic

    Although I haven't had the stress as others have described, several years before my diagnosis, I had four or five years of extreme stress due to financial conditions which I had no control over.  I think it was the lack of control which created the stress for me.  Did my family history of cancer and that stress affect my immune system and have an impact on my diagnosis?  Maybe.  I do wonder about that.  Although my financial difficulties have been resolved, I do now try to find ways to avoid or limit stress in my life.   

  • janie1
    janie1 Member Posts: 753 Member

    In his book "Outliers"...

    it was the town Roseta, PA.  He decided that it was the social and communal nature of life in that town that led to the low rates of heart disease (although basically the whole town was populated by people who descended from one family in Italy, so I'm not sure if there's any way to disentangle the role of genetics from that of enivronment in this particular case).

    "the whole town was populated

    "the whole town was populated by people who descended from one family"........

    Now's there's a topic a TV series could be written about. :)

  • annalexandria
    annalexandria Member Posts: 2,571 Member
    janie1 said:

    "the whole town was populated

    "the whole town was populated by people who descended from one family"........

    Now's there's a topic a TV series could be written about. :)

    Def sounds like a TV show....

    probably one of those reality ones that are so popular these days!

  • manwithnoname
    manwithnoname Member Posts: 402

    In his book "Outliers"...

    it was the town Roseta, PA.  He decided that it was the social and communal nature of life in that town that led to the low rates of heart disease (although basically the whole town was populated by people who descended from one family in Italy, so I'm not sure if there's any way to disentangle the role of genetics from that of enivronment in this particular case).

    That's right

    Don't have the book at hand, gave it away, but I thought genetics had been ruled out, that the town and surrounding towns all came from the same area but Roseta was the most social. 

    There is a Greek Island with a similar story http://www.bbc.co.uk/news/magazine-20898379 check out the guys cancer story.

  • bspangler47
    bspangler47 Member Posts: 145
    YoVita said:

    Great thoughtful topic

    Although I haven't had the stress as others have described, several years before my diagnosis, I had four or five years of extreme stress due to financial conditions which I had no control over.  I think it was the lack of control which created the stress for me.  Did my family history of cancer and that stress affect my immune system and have an impact on my diagnosis?  Maybe.  I do wonder about that.  Although my financial difficulties have been resolved, I do now try to find ways to avoid or limit stress in my life.   

    Stress

    Hi Everyone,

    Well everyone on 16 Jan 2012, I turned the big 50 and still in resmission from coloreactal CA.  So we celebrated alot on my birtthday.  I was reading some of the postings regarding stress.  I do believe it does cause alot of grief in our lives.  The type of cancer I had didnt run n my family both my Moms and Dads,  I was active duty Army, when I was about the cancer.  Yrs before that I was going thru a horrible divorce and custodu battle.  Which added more stress, had another child.  Communicated along distance betweeen work and home.  Not enough money to go around.  Then long trip rides to see family, which I was the only driver, drove from southern california to Northern Idaho.  Then PCS'd from Southern CA to El Paso Texas.  Then several trips to GA, to Northern Idaho thru New Mexcio etc.  Plus from Ft Bliss to Ft Hood several times.  That also added to my colorecation CA.  Plus being a single Mom.

     

    Now I am trying to learn how not to stress out so much.  I have started to take antidepressants to see if that helps out.  Keep a positive outook

     

  • jen2012
    jen2012 Member Posts: 1,607 Member
    Yeah not just cancer but all

    Yeah not just cancer but all illness.  I don't think it's a coincidence that our son was diagnosed with type 1 diabetes just a couple of months after my husband's cancer diagnosis.   They say it's auto-immune and it would have come out eventually anyhow - I just think the stress made it come out now.  

    And I know what you mean about the drama and being a hoax!  We have had so much happen from Sept 2011 to now that we don't even tell people any more, in fear that they think we are making things up!   It's ridiculous - I feel like we have a big ugly cloud hanging over our heads at times.  But like you Ann, one of those things being the greatest surprise of our lives....our little boy born last year when I was 43 - he's amazing and keeps us laughing! 

  • Momof2plusteentwins
    Momof2plusteentwins Member Posts: 509 Member
    Stress!
    My surgeon told me that my tumor has been growing for years, so maybe the stress that people had years ago contributed to immune system being down and the start of a tumor.
    My stress was from my first husband that I married at age 18 and met at age 15. He was 5 years older and was a cop. Our marriage was always rocky but still had 2 kids with him. He ended up having an affair for years and wanted both of us, family and mistress. I filed for divorce and he didnt like that, he stopped a women on I95 in Florida and rapping her and strangling her. I was left with a 6 year old and 3 year old and a husband with 25 years to life. Could be a book right? Well it is, Ann Rule wrote a book - "You belong to me". Enough about that, have been happily married for 19 years to a wonderful man and we have 15 year old twins.
    Sandy:)
  • annalexandria
    annalexandria Member Posts: 2,571 Member
    jen2012 said:

    Yeah not just cancer but all

    Yeah not just cancer but all illness.  I don't think it's a coincidence that our son was diagnosed with type 1 diabetes just a couple of months after my husband's cancer diagnosis.   They say it's auto-immune and it would have come out eventually anyhow - I just think the stress made it come out now.  

    And I know what you mean about the drama and being a hoax!  We have had so much happen from Sept 2011 to now that we don't even tell people any more, in fear that they think we are making things up!   It's ridiculous - I feel like we have a big ugly cloud hanging over our heads at times.  But like you Ann, one of those things being the greatest surprise of our lives....our little boy born last year when I was 43 - he's amazing and keeps us laughing! 

    Congrats on your little guy...

    ours is now 8, and he's just the light of my life.  Never would have planned to get pregnant at 38, nine years after my last child, but it's really worked out for us.

  • annalexandria
    annalexandria Member Posts: 2,571 Member

    Stress

    Hi Everyone,

    Well everyone on 16 Jan 2012, I turned the big 50 and still in resmission from coloreactal CA.  So we celebrated alot on my birtthday.  I was reading some of the postings regarding stress.  I do believe it does cause alot of grief in our lives.  The type of cancer I had didnt run n my family both my Moms and Dads,  I was active duty Army, when I was about the cancer.  Yrs before that I was going thru a horrible divorce and custodu battle.  Which added more stress, had another child.  Communicated along distance betweeen work and home.  Not enough money to go around.  Then long trip rides to see family, which I was the only driver, drove from southern california to Northern Idaho.  Then PCS'd from Southern CA to El Paso Texas.  Then several trips to GA, to Northern Idaho thru New Mexcio etc.  Plus from Ft Bliss to Ft Hood several times.  That also added to my colorecation CA.  Plus being a single Mom.

     

    Now I am trying to learn how not to stress out so much.  I have started to take antidepressants to see if that helps out.  Keep a positive outook

     

    That is a lot going on...

    and I really admire you for going through all of this as a single mom.  My niece is raising her baby solo right now, and it's just so hard.  I have way more respect now for my own mom (parents split up when I was four), doing it all on her own.  It takes a special kind of strength to be a single parent.

  • annalexandria
    annalexandria Member Posts: 2,571 Member

    Stress!
    My surgeon told me that my tumor has been growing for years, so maybe the stress that people had years ago contributed to immune system being down and the start of a tumor.
    My stress was from my first husband that I married at age 18 and met at age 15. He was 5 years older and was a cop. Our marriage was always rocky but still had 2 kids with him. He ended up having an affair for years and wanted both of us, family and mistress. I filed for divorce and he didnt like that, he stopped a women on I95 in Florida and rapping her and strangling her. I was left with a 6 year old and 3 year old and a husband with 25 years to life. Could be a book right? Well it is, Ann Rule wrote a book - "You belong to me". Enough about that, have been happily married for 19 years to a wonderful man and we have 15 year old twins.
    Sandy:)

    Oh. My. God.

    That is just horrible, Sandy!  What a terrible, traumatic thing for your family to have to go through.  How old are your kids from that marriage now?  Are they doing ok?  I thought my life sounded crazy, but this is a good reminder for all of us that things can be worse.  I'm just so sorry you had to expereince something like this (but am very glad it wasn't you that he murdered...as it so often is with this kind of situation).  Many hugs.

  • wawaju04976
    wawaju04976 Member Posts: 316 Member

    Stress!
    My surgeon told me that my tumor has been growing for years, so maybe the stress that people had years ago contributed to immune system being down and the start of a tumor.
    My stress was from my first husband that I married at age 18 and met at age 15. He was 5 years older and was a cop. Our marriage was always rocky but still had 2 kids with him. He ended up having an affair for years and wanted both of us, family and mistress. I filed for divorce and he didnt like that, he stopped a women on I95 in Florida and rapping her and strangling her. I was left with a 6 year old and 3 year old and a husband with 25 years to life. Could be a book right? Well it is, Ann Rule wrote a book - "You belong to me". Enough about that, have been happily married for 19 years to a wonderful man and we have 15 year old twins.
    Sandy:)

    Wow. I have read that book. I

    Wow. I have read that book. I really like Ann Rule (sorry you had to be a subject in one of her books). I hope your older kids are doing ok.

    Judy