Clinical trial BMS936558 (MPDL3280A)(MDX1106)--you know, the anti-PDL1 drug!
For a short review, I was diagnosed with CCRCC in May 2011, had my kidney removed at Duke in July, and went back home to Atlanta in August. I took Sutent for 10 months for mets in my lungs. Had a great response for about 9 months. When remaining tumors showed growth in June, I took Inlyta for two months. Got NO response; in fact two nodules that had almost disappeared have begun to grow again.
So instead of going with another drug that cannot cure me and can only work for a matter of time, I opted to donate my body to science BEFORE I die (which I don't plan to do anytime soon, I might add). I feel especially lucky to be going for the cure. Not sure of all the details yet. I will know more on Friday and will report back and let you all know how it goes. Fox has explained in his threads how this drug works. And he also has been a real friend to me when the going got tough. These boards are such a safe and wonderful place to meet kindred souls.
I intend to FLY as my good friend would say!
Much love and prayers to all.
Paula
Comments
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Yeahalice124 said:YES!!!
Paula,
I am thrilled you're getting into one of the MDX-1106/BMS936558 trials! And with Fox as a coach--it doesn't get better! Get that suitcase packed. Congratulations!!!! I'm really happy for you.
I'm happy for you to get the chance to try a very promising drug. I am also on a trial sutent / mdx 1106. I get my first scans in a week and a half, be ready for some positive results from me!!0 -
Wonderful newstacyarts said:Yeah
I'm happy for you to get the chance to try a very promising drug. I am also on a trial sutent / mdx 1106. I get my first scans in a week and a half, be ready for some positive results from me!!
This is great to hear. I will be in that hospital getting my Interleukin!! Best wishes and many prayers coming your way!!!0 -
I would love to meet you but..NanaLou said:Wonderful news
This is great to hear. I will be in that hospital getting my Interleukin!! Best wishes and many prayers coming your way!!!
I am going to Sarah Cannon Research Institute, across the street from Vanderbilt. Besides, I'm guessing you won't be up to meeting online friends right about then!
Maybe on another visit we can connect. I wish you only the best!!! XO 0 -
Tacyarts...tacyarts said:Yeah
I'm happy for you to get the chance to try a very promising drug. I am also on a trial sutent / mdx 1106. I get my first scans in a week and a half, be ready for some positive results from me!!
I'm expecting great things for you. Sutent walloped my cancer for 10 months! That along with the mdx1106 will move you to the head of the class!0 -
Good luckpjune127 said:Tacyarts...
I'm expecting great things for you. Sutent walloped my cancer for 10 months! That along with the mdx1106 will move you to the head of the class!
Hope you get the best possible response0 -
Get ready to kick some cancer butt!!
Paula,
I am excited for you and I know you will be giving cancer the old heave ho very soon!! Keep that big smile and positive attitude going they are powerful weapons in this battle.
I hafta ask; Who's this science guy that you donated your body to and does he have a sister that would take mine?
You are in my thoughts and prayers.
Godspeed,
Gary0 -
The science guygarym said:Get ready to kick some cancer butt!!
Paula,
I am excited for you and I know you will be giving cancer the old heave ho very soon!! Keep that big smile and positive attitude going they are powerful weapons in this battle.
I hafta ask; Who's this science guy that you donated your body to and does he have a sister that would take mine?
You are in my thoughts and prayers.
Godspeed,
Gary
is really Sarah Cannon Research Institute in Nashville, Tennessee. It is a research institute designed only for clinical trials, so the work is fast, efficient, and clean. I had never heard of it, but people in the "business" say it is a gem of a place.
I'll bet they would take your body if you asked nicely and passed all the entrance exams. Would love to have a buddy there with me!
Love, Paula0 -
AWESOME NEWS!
Paula, What great news to wake up to this morning!
We'll be sending positive vibes from up here in Ottawa. Go kick it to the curb!
Kim0 -
Yahoo!!!
I'm THRILLED for you, Paula! Atta girl! Go get 'em! We'll all be here rooting for you and waiting to hear how it goes. (is that your son in your photo?
He's ADORABLE.) Sending hugs & good thoughts.0 -
Omigosh...you made my dayI am alive said:Yahoo!!!
I'm THRILLED for you, Paula! Atta girl! Go get 'em! We'll all be here rooting for you and waiting to hear how it goes. (is that your son in your photo?
He's ADORABLE.) Sending hugs & good thoughts.
That is my grandson! My son is 36 years old. That was a HUGE compliment! I love you!0 -
OMG. IN that photo you lookpjune127 said:Omigosh...you made my day
That is my grandson! My son is 36 years old. That was a HUGE compliment! I love you!
OMG. IN that photo you look like you're 34 yrs. old!0 -
WOW!pjune127 said:Omigosh...you made my day
That is my grandson! My son is 36 years old. That was a HUGE compliment! I love you!
Paula, glad to hear you are going for the MDX. I hope soon it is standard treatment as it seems to do well, and very importantly, the side affects are tolerable! You serious that is your grandson? I have to agree, you look VERY young! Good for you, that means you have the strength to pull this off! Go get em! xxoo0 -
WOWangec said:WOW!
Paula, glad to hear you are going for the MDX. I hope soon it is standard treatment as it seems to do well, and very importantly, the side affects are tolerable! You serious that is your grandson? I have to agree, you look VERY young! Good for you, that means you have the strength to pull this off! Go get em! xxoo
See. Don't always need jokes to make people smile and feel good. Pretty face, great attitude, and loving family. Thats our Paula!
Reminds me of a music video a few years back. Rachael Hunter pays some teenagers mom. His friends are awestruck with her as she struts around the swimming pool in her bikini. She couldn't POSSIBLY be THAT old!
I'm smiling. Bet you are too!0 -
Yes I am smiling!foxhd said:WOW
See. Don't always need jokes to make people smile and feel good. Pretty face, great attitude, and loving family. Thats our Paula!
Reminds me of a music video a few years back. Rachael Hunter pays some teenagers mom. His friends are awestruck with her as she struts around the swimming pool in her bikini. She couldn't POSSIBLY be THAT old!
I'm smiling. Bet you are too!
I am proud of my 61 years! And seriously want at least 20 or 30 more. I want to watch that little guy grow up and I want to be at his sister's wedding. (They are 4 and 6.) Funny though, sometimes I am with my son and people think we are brother and sister. While that makes me feel great, Scott is not quite sure how to handle it. I just smile.
Love to you all. Off to Tennessee this afternoon for tomorrow's early appointment. You guys will be the first to know! XXOO0 -
Smiling!pjune127 said:Yes I am smiling!
I am proud of my 61 years! And seriously want at least 20 or 30 more. I want to watch that little guy grow up and I want to be at his sister's wedding. (They are 4 and 6.) Funny though, sometimes I am with my son and people think we are brother and sister. While that makes me feel great, Scott is not quite sure how to handle it. I just smile.
Love to you all. Off to Tennessee this afternoon for tomorrow's early appointment. You guys will be the first to know! XXOO
It's a crafty dodge to pretend that that picture of your young Daughter-in-Law is really you but nobody's buying it Paula
Looking forward to sunshine from Tennessee and to you joining Fox on the rostrum (but he might not welcome it because you're gonna make him look so very, very old!!)0 -
Paula and the fox...Texas_wedge said:Smiling!
It's a crafty dodge to pretend that that picture of your young Daughter-in-Law is really you but nobody's buying it Paula
Looking forward to sunshine from Tennessee and to you joining Fox on the rostrum (but he might not welcome it because you're gonna make him look so very, very old!!)
May they both grow very old together!!!0 -
Paula and Foxygarym said:Paula and the fox...
May they both grow very old together!!!
Fox could be forgiven for being tempted by that idea but I bet his Wife would have something to say about it!0 -
Tex, Tex, Tex...Texas_wedge said:Paula and Foxy
Fox could be forgiven for being tempted by that idea but I bet his Wife would have something to say about it!
You really are a dirty (not so old) man...LOL0
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