For those who are In Xeloda or those who are Sceptic about Xeloda.

pepebcn
pepebcn Member Posts: 6,331 Member
in Colorectal Cancer #1
I have finished just my first round of Xeloda +Avasin , not too strong drug, but just in one round CEA dropped From 64 to 30 this is a 60% in only one round. Don't miss Hope!
hugs to all.

Comments

  • johnnybegood
    johnnybegood Member Posts: 1,117 Member
    #2
    im still
    hanging onto hope pepe with the same chemo you are on.right now i am on a low dosage of xeloda and avastin and my latest scan shows all lesions in both lungs are holding steady(no growth)so i am glad for you and and yes please dont loose hope...Godbless...johnnybegood
  • janie1
    janie1 Member Posts: 753 Member
    #3
    johnnybegood said:

    im still
    hanging onto hope pepe with the same chemo you are on.right now i am on a low dosage of xeloda and avastin and my latest scan shows all lesions in both lungs are holding steady(no growth)so i am glad for you and and yes please dont loose hope...Godbless...johnnybegood

    Sounds Good!
    Thanks for sharing. That sounds very good. Best to both of you.
    Yes, keep the hope alive.
  • Lovekitties
    Lovekitties Member Posts: 3,364 Member
    #4
    Dear Pepe
    So very glad to hear your good news!

    Praying that it continues to work as well or even better in the weeks to come.

    Hugs,

    Marie who loves kitties
  • Doc_Hawk
    Doc_Hawk Member Posts: 685
    #5
    Xeloda
    Congrats Pepe,

    Glad to hear that it's working great for you. I don't know that I'll ever be able to go one Xeloda, and to be honest, not sure that I want to. I've heard the side effects are worse with blistering on the feet. I'd be very interested to see how you react to it as your treatment progresses.

    Doc
  • smokeyjoe
    smokeyjoe Member Posts: 1,425 Member
    #6
    Doc_Hawk said:

    Xeloda
    Congrats Pepe,

    Glad to hear that it's working great for you. I don't know that I'll ever be able to go one Xeloda, and to be honest, not sure that I want to. I've heard the side effects are worse with blistering on the feet. I'd be very interested to see how you react to it as your treatment progresses.

    Doc

    Good news Pepe. I think
    Good news Pepe. I think taking a pill would be better than infusion (I just hated infusions) Glad this is working for you. I would have liked to have been put on that. Keep us posted.
  • dmj101
    dmj101 Member Posts: 527 Member
    #7
    So Happy for you! 60 % is an
    So Happy for you! 60 % is an awesome accomplishment.. congratulations
    Xeloda is 5FU... in a pill form..
    I hope the hand foot condition and stomach issues don't come your way..
    When you say first round.. how long have you been on it..
    I don't really think pill is good for me.. but my CEA is non reactive so I can't tell from a blood test how I am doing.
    I had hand/foot from the IV form that I didn't know was it till I got the Xeloda paraphenalia- when my old onc put me on it.. but my new onc didn't think I should be on at at this time. so we stopped it..
    Best of luck to you!!!
  • pepebcn
    pepebcn Member Posts: 6,331 Member
    #8
    dmj101 said:

    So Happy for you! 60 % is an
    So Happy for you! 60 % is an awesome accomplishment.. congratulations
    Xeloda is 5FU... in a pill form..
    I hope the hand foot condition and stomach issues don't come your way..
    When you say first round.. how long have you been on it..
    I don't really think pill is good for me.. but my CEA is non reactive so I can't tell from a blood test how I am doing.
    I had hand/foot from the IV form that I didn't know was it till I got the Xeloda paraphenalia- when my old onc put me on it.. but my new onc didn't think I should be on at at this time. so we stopped it..
    Best of luck to you!!!

    dmj, for the moment just tired and some manageable diarrhea ,
    When I say 1 round means as you know two straight weeks and one off! Still 15 weeks ahead!
    Hugs!
  • Coppercent
    Coppercent Member Posts: 158
    #9
    Should not be skeptical!
    I would not be skeptical about Xeloda! I was on it for 6 weeks with my radiation and it did it's job! And I was on it for adjuvent chemo post surgery due to other medical conditions. I am now in remission and doing well. My CEA levels always remained in the normal levels while taking it. I did not have any side effects with the Xeloda. Although my highest dose was only 3500 so that may have been the reason. Although I thnk that number is based on weight. I was also pretty strict about doing the side effect preventative stuff. It worked well for me and I was able to maintain my normal lifestyle.
  • tommycat
    tommycat Member Posts: 790 Member
    #10
    Gooooooooooooooo Pepe!
    Tell your body to keep up the good work :)
    Thanks for sharing,
    Tommycat
  • Annabelle41415
    Annabelle41415 Member Posts: 6,742 Member
    #11
    Great
    That is wonderful news and it sounds like you are tolerating it too. Hope it continues to do well for you.

    Kim
  • dmj101
    dmj101 Member Posts: 527 Member
    #12
    pepebcn said:

    dmj, for the moment just tired and some manageable diarrhea ,
    When I say 1 round means as you know two straight weeks and one off! Still 15 weeks ahead!
    Hugs!

    ok.. sounds good.. my onc
    ok.. sounds good.. my onc had me doing one week on one week off..
    so that is great results.
    I wish you much continued success..
  • smokeyjoe
    smokeyjoe Member Posts: 1,425 Member
    #13
    Annabelle41415 said:

    Great
    That is wonderful news and it sounds like you are tolerating it too. Hope it continues to do well for you.

    Kim

    Xeloda + Celebrex(R)
    Xeloda + Celebrex(R) (celecoxib)
    Data presented by Dr. E. Lin of M.D. Anderson Cancer Center and his team
    show that the combination of Xeloda and Celebrex (celecoxib) significantly
    increased the time to tumor progression to six months, versus 3 months without
    Celebrex, and the rate of disease stabilization to 62.5 percent, versus 22.8
    percent without Celebrex, for patients with metastatic colorectal cancer.
    In addition, the patients treated with the combination of Xeloda and Celebrex
    experienced less Grade 1 to 2 hand-foot syndrome and diarrhea. The study was
    a retrospective analysis of 67 patients with metastatic colorectal cancer who
    were either taking Xeloda in combination with Celebrex or Xeloda monotherapy.
    Celebrex is a COX-2 specific inhibitor approved for both osteoarthritis
    (OA) and adult rheumatoid arthritis (RA) and for the management of acute pain.
    Celebrex is also approved for the treatment of familial adomenal polyposis
    (FAP), a rare and devastating genetic disease of the colon.
  • dmj101
    dmj101 Member Posts: 527 Member
    #14
    smokeyjoe said:

    Xeloda + Celebrex(R)
    Xeloda + Celebrex(R) (celecoxib)
    Data presented by Dr. E. Lin of M.D. Anderson Cancer Center and his team
    show that the combination of Xeloda and Celebrex (celecoxib) significantly
    increased the time to tumor progression to six months, versus 3 months without
    Celebrex, and the rate of disease stabilization to 62.5 percent, versus 22.8
    percent without Celebrex, for patients with metastatic colorectal cancer.
    In addition, the patients treated with the combination of Xeloda and Celebrex
    experienced less Grade 1 to 2 hand-foot syndrome and diarrhea. The study was
    a retrospective analysis of 67 patients with metastatic colorectal cancer who
    were either taking Xeloda in combination with Celebrex or Xeloda monotherapy.
    Celebrex is a COX-2 specific inhibitor approved for both osteoarthritis
    (OA) and adult rheumatoid arthritis (RA) and for the management of acute pain.
    Celebrex is also approved for the treatment of familial adomenal polyposis
    (FAP), a rare and devastating genetic disease of the colon.

    Good info Smokey...

    Good info Smokey...
  • taraHK
    taraHK Member Posts: 1,952 Member
    #15
    Excellent!
    What a fantastic drop in CEA after one round! Congratulations! And glad you had minimal side effects. I was on that combination previously. I tolerated it very well. And I loved taking a pill rather than being on a drip (especially a 48 hr drip). Eventually I did end up with sore feet (blisters on the bottom of my feet). But that took a long time. I'd do it again, if I could.

    Tara
  • jjaj133
    jjaj133 Member Posts: 867 Member
    #16
    Woohoo Pepe! Wonderful
    Woohoo Pepe! Wonderful news. I was one Xeloda for 8 months before my feet started to get red and peel. i was lucky enough to be able to stop it. That was November and so far so good.
    Keep up the good work my friend.
    Judy

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