Clinical trial for TRC105 Phase 1b

mukamom
mukamom Member Posts: 402
in Colorectal Cancer #1
Robert is a candidate for a trial in Birmingham @ UAB. This new drug works like Avastin. We weren't too sure about doing this trial since we don't know if the increased tx with Erbitux and Camptosar is working, yet. But Robert's onc said he worked with this drug in a trial last year for prostate cancer and the results were pretty impressive. He was very excited about it and knows the doc that is heading the trial and recommended Robert do it.

So next week, it is another ballgame. New facility, new docs, more scans and tests.

Will keep updates posted.

Angela

Comments

  • steved
    steved Member Posts: 834 Member
    #2
    Interesting
    IS interesting to see another anitangiogenesis drug being trialled. It is early days if it is only phase 1b but the tolerability trials on this drug I could find look good. There is little in the literature that I can access on its efficacy in colorectal cancer (or others though your onc may know some unpublished data).

    Would like to hear more if you can get some more info. Am reading a bit on two other new chemos that are working on the angiogenesis pathways and seems to be the big area of development at present. I am sure the companies will be competing to see who can get their drug to market first.

    Is all good news for us though as has been a long period of little new for colorectal cancer.

    steve
  • mukamom
    mukamom Member Posts: 402
    #3
    steved said:

    Interesting
    IS interesting to see another anitangiogenesis drug being trialled. It is early days if it is only phase 1b but the tolerability trials on this drug I could find look good. There is little in the literature that I can access on its efficacy in colorectal cancer (or others though your onc may know some unpublished data).

    Would like to hear more if you can get some more info. Am reading a bit on two other new chemos that are working on the angiogenesis pathways and seems to be the big area of development at present. I am sure the companies will be competing to see who can get their drug to market first.

    Is all good news for us though as has been a long period of little new for colorectal cancer.

    steve

    This is being
    trialled for advanced solid tumors. Robert has multiple hepatic lesions, the largest being 6x4 cm that is unresectable due to the hepatic veins snaking through it.

    We remain hopeful.

    Best to you, Steve

    Angela
  • idlehunters
    idlehunters Member Posts: 1,787 Member
    #4
    mukamom said:

    This is being
    trialled for advanced solid tumors. Robert has multiple hepatic lesions, the largest being 6x4 cm that is unresectable due to the hepatic veins snaking through it.

    We remain hopeful.

    Best to you, Steve

    Angela

    Hey Angela
    Thanks for the update. Yes, please keep us informed on this information. I think this is a great opportunity for you guys and this just may be an awesome new tool. I am excited for you both! Take care

    Jennie
  • janie1
    janie1 Member Posts: 753 Member
    #5
    idlehunters said:

    Hey Angela
    Thanks for the update. Yes, please keep us informed on this information. I think this is a great opportunity for you guys and this just may be an awesome new tool. I am excited for you both! Take care

    Jennie

    Hoping for the best. Will
    Hoping for the best. Will keep you in my prayers. Good news that your new onc is upbeat on this and has the experience.

Discussion Boards