Pete- or Tans or anyone's feedback

pete43lost_at_sea said:

you had to ask this, GREAT question janie
thanks for asking, i will share my cimetidine story so far, it may change tomorrow.

i have been off on off on off

i am off it now because i have had recurring dysbiosis.

yes it reduces stomach acid, and you can boost tanstafl has explained mentioned many bits and pieces about cimetidine and i will let him comment.

just google ppi and warning, my functional gp told me about this and was not convinced
by all the studies i had proving how good cimetidine was, even the lef advisory about colorectal protocols, documented here recently has it in. when i quizzed the lef onc about it, he said it was a disputed point. i emailed lef about this and never got a response.

LEF EMAIL AND BLOG
i hope you are well and lef is making progress.

i have been on the most amazing toxicology conference in the states and am sorting out my toxicants heavy metals and pcbs eta.

http://petertrayhurn.blogspot.com.au/2012/03/going-to-see-philip-day-friday-18th.html#!http://petertrayhurn.blogspot.com/2012/03/lef-needs-to-review-cimetidine-for.html

I would sincerely appreciate an answer, as i suspect todds advice is correct from the conference.

the entire conference mp3 is on my blog, take a copy and the cimetidine advice is in the second last recording. its a great listen for most cancer patients.

by the way, most colorectals have had folfox, see my blog for the discussion on platinum poisoning after folfox.

you could put this up as a good story as what your onc does not tell you, and what you can find when you start taking responsibility for your own health.

thanks again to all the guys andgals at lef, my health at the moment is improvioing, largely due to your support and advice.


So here is the PPI warning
http://www.medicalnewstoday.com/articles/233272.php

I could not confirm my lewis status.
I had some significant decrease in my sex life. Given that i have given up drugs, grog and all the food i used to eat for this healthy cancer battle. i was dammed if i would given up sex. for some guys cimetidine is pretty devastating in that area. I think the sex issue is only a guy problem. even my onc was giggling about my sex problems in the last consult with my wife when we talked about me going off cimetidine. she said its common knowledge.

see the recent posts somewhere here about probiotics and an acid environment screwing the good bugs, their goes your immune system and a background load of toxins on your liver. so getting the acid balance correct is something i want to leave to mother nature and god. but i will be interested in tanstafl comments.

so i have digestive enzymes , a few types and will get back onto them,
i also have some hcl pepsin. when i was trying to play god.
i have off these as i have been doing advanced stool tests to get to the bottom of the recurring dysbiosis and they want your gut the way it is naturally without supplements.

in theory these all help, but as you said acid is key to nutrient absorption. if you just eat western crap food, then it makes little difference.

if you care about your body, you want to give it essential minerals, vitamins etc etc etc.
if you eat well, organic, vegan, juice, some supplements well its a waste of money if you poo them down the loo and the goodness does not get into the plasma, and then to the cells that needs the goodies.

so i am off cimetidine temporarily. expecting it to be a long break.

so read read read, get lots of advice most of it conflicting.

welcome to colorectal survivorship in the twenty first century.

hugs,
pete

ps so i have drop aspirin and cimetidine, but today i have picked up iodine and b12
its not a good day if i don't pop a few hundred pills. we got to keep the supplement makers in business or else a big part of the us economy would grind to a halt. only joking!

pps this link is real good at explaining phase detox
http://www.health-diets.net/database/detoxification/

ppps goto my blog and search cimetidine, i was really surprised how much it came up.
the lef link is below
http://www.blogger.com/blogger.g?blogID=2969302819198622741#editor/target=post;postID=7717452709949402681

tanstaafl said:

prior discussions
Previous cimetidine discussions, including some on digestion and vitamin
Cimetidine use
cimetidine and digestion 101

My wife was surely vitamin D deficient before diagnosis (like siblings), and has required substantial amounts of vitamin D3 supplements while on chemo and cimetidine to even get minimum acceptable vitamin D blood levels.

We opted to get a prescription for very high dose vitamin D3, as an alternative treatment addition to the chemotherapy to additionally stress the cancer cells. We check her blood calcium levels monthly.

tanstaafl said:

blood calcium
Blood calcium is considered a cheaper, more direct measure of potential vitamin D and calcium supplement problems. The background concern is that high levels of vitamin D and a high supplement intake of calcium might lead to hypercalcemia. Calcium blood levels somewhat above the normal range for calcium cause concern, and then at too high levels, form solid calcium salts in the kidney - "calcium toxicity".

The solubility is figured simplistically as a product of [calcium] x [phosporus], and this product is what the "pros" use in tracking hypercalcemia on close calls. From a bone formation point of view magnesium and vitamin K2 are important ingredients and both help balance calcium and vitamin D3 levels in the body.

Chemo makes it hard to keep vitamin D3 and calcium adequate for my wife by normal diet alone. Supplemental vitamin D3 and calcium tradeoffs need to be done by knowledgeable persons and monitored. We use a lot of vitamin D3, balanced with magnesium and vitamin K2, and avoid calcium supplements - my wife sometimes gets a fair amount of calcium in other supplements. Erratic use of the supplements with calcium stabilizers (e.g. pancreatin and betaine HCl) causes swings in her calcium blood levels above/below the mid point, but always within range.

smokeyjoe said:

Okay...I was just looking at
Okay...I was just looking at my bloodwork that I have...I just noticed in July my CEA was .5, I never realized it had gotten that low!! Wow. Now, I'm wondering what it is now, that result wasn't ready when I left my appt. this week. With the calcium last July it was 2.45 it's now at 2.29....so it's basically dropped ...wonder if the cimitidine I'm on recently is causing this drop.... who knows.

pete43lost_at_sea said:

i think cimetidine is more like preventitive and cytotoxic
its strong point for us cancer was avoiding local immune suppression.
now i guess if you take it,
and it suppresses a tumours local immuine suppression than in principle it should
that tumour to be gobbled by the immune system and indeed you could see decreasing cea's and or a flare as we have discussed here. it depends on where the tumour is in rerlation to the blood supply and the liver.

hugs,
pete

tanstaafl said:

steady as she goes
The fundamentals of cimetidine (for more continuous protection against met cells) suggest to us that more constant level is better. We lean that way on vitamin D3 also.