My husband was diagnosed March 2011, stage 4 pc. Psa 1913, gleason 9, you get the picture. He is 59 now, and has been on ht since late March. Psa has remained less than 1 with monthly screenings thru Dec. Last week he tested at psa 2.2. Doc says not to worry, we wait till next test March 5, to see how fast it is rising. Zoladex and Xgeva are his only treatments to date. Casadex was dropped after initial 14 days. Says we may reintroduce the Casadex next month. My biggest worry, he started with Dr. Reid, who sold his practice and moved back to the east coast to head up two hospitals. Our new doc, all her experience has been as a hospitalist. Not many choices here in AR. Am I exagerating the worry factor here? Is 2.2 not bad as the nurse said.