Sky high CEA

yes
People can have that high of cea, not uncommon. It will come down with chemo and surgeries. Takes time. Fluctuations are normal.
I saw that you said you were in the "middle of the country". I tried researching how many centers use the HAI therapy. Sloan, for sure.
And looks like University of Pittsburgh. Maybe University of Wisconsin (at Madison).....i thought i read an old post on another site, where someone had that treatment in Wisconsin. I'm also looking into .... if this is done in San Diego, however, that isn't so close to you. As you can see, very few oncologists use HAI therapy. I don't know if that is because of how closely it needs to be monitored. Many doctors probably just don't want to deal with it. Don't know much about SIRT. Was wondering if she could have liver sections taken out. Doesn't seem like 4 lesions would necessarily make her inoperable. Some people start with having chemo first. (This is just a quick answer, others will chime in, too)

Varmint5 said:

Thanks, Janie...
She has "many" liver spots, two larger ones which were approx 6-7cm in the beginning, now less than half that. Some of the smaller liver spots appear to be gone. All have shrunk to less than half and the radiation oncologist said, from CT scan, "appear to be dying." She started immediately on Folfox, then 28 rad treatments after two doses of Folfox. Are fluctuations of 300 points normal?

Scans are better to go by
Scans are better to go by anyway, especially this early, and with having radiation....cea probably doesn't mean much, but it's good to have it. Good... tumors are shrinking a lot. No doubt about it, it's a long, slow, one-day-at-a-time process. Wish we could speed it up, but just have to settle-in. In the meantime, everyone enjoy the times when you are not at appointments.