The new miracle drug for cancer (no sarcasm!)

NayPaul said:

yeah!
My wife tested positive for the mutation last week after testing negative 5 months ago..... and yes.... this is a "miracle drug" that should not be withheld.

Good news
I am very pleased for everyone who needs it and hope you all can get it.

I am very worried over my
I am very worried over my friend. I feel the subject staying calm is very appropriate.
She has stage 4 non small cell carcinoma of the lungs. Tarceva worked for about 8 months.2 different chemos and now to try for a experimental drug (but which one) ?
At this time she is doing great and has only shortness of breath.Vital signs good, no fever, pneumonia one time.
I am very anxious to what others are using that gives more extension for life and quality.I wish for a miracle and there is always that hope as we need more miracles in our lifetime.If you have any advise to give or any thing that could help please email me. I wish you , yourself the best and hope to find on here inspiration.

NayPaul said:

yeah!
My wife tested positive for the mutation last week after testing negative 5 months ago..... and yes.... this is a "miracle drug" that should not be withheld.

started today
My wife started xalkori/crizotinib today. She was enrolled in the study last Thursday and pfizer closed it to new entrants after the fda approval. Her health has declined rapidly the last 6 weeks, new scans indicated growth and new growths in many places.... enough that there is no way she can walk her marathon.... but she is looking at another marathon in november assuming crizotinib works. I never doubt my wifes dedication.

lekkerone said:

NayPaul
My very best to your wife as she starts on this new drug. I don't doubt you two for a minute as you are an amazing pair. Diane

Best of luck
Wishing your wife the best of luck with the new drug and I'll be praying that she can walk the marathon in November. She is such an incredible woman!!!

NayPaul said:

started today
My wife started xalkori/crizotinib today. She was enrolled in the study last Thursday and pfizer closed it to new entrants after the fda approval. Her health has declined rapidly the last 6 weeks, new scans indicated growth and new growths in many places.... enough that there is no way she can walk her marathon.... but she is looking at another marathon in november assuming crizotinib works. I never doubt my wifes dedication.

Thoughts and prayers!!
NayPaul,
Lifting you both up in thought and prayers! Looking for positive outcomes with crizotinib so that you and your wife will have a lifetime marathon. Stay strong and know we are here. God bless.
Cheryl

grannylove said:

Thoughts and prayers!!
NayPaul,
Lifting you both up in thought and prayers! Looking for positive outcomes with crizotinib so that you and your wife will have a lifetime marathon. Stay strong and know we are here. God bless.
Cheryl

Thank you.
It's been an up and down week. She was pretty much out of commission the first few days of the drug. Then Monday, she did very well. We went to the zoo, she was up all day etc. But starting yesterday afternoon she has faultered. She is having trouble keeping things down, so I have to plan the meds at the right time. I'm going to try and take her in tommorrow to get some fluids. She is losing a lot of weight and seems dehydrated. I do believe Crizotinib is her best chance so I want to keep getting this into her.

Thanks again.

persion said:

I am very worried over my
I am very worried over my friend. I feel the subject staying calm is very appropriate.
She has stage 4 non small cell carcinoma of the lungs. Tarceva worked for about 8 months.2 different chemos and now to try for a experimental drug (but which one) ?
At this time she is doing great and has only shortness of breath.Vital signs good, no fever, pneumonia one time.
I am very anxious to what others are using that gives more extension for life and quality.I wish for a miracle and there is always that hope as we need more miracles in our lifetime.If you have any advise to give or any thing that could help please email me. I wish you , yourself the best and hope to find on here inspiration.

i am on tarceva now did it
i am on tarceva now did it work pretty good then? the side affects are kicking me.

NayPaul said:

Thank you.
It's been an up and down week. She was pretty much out of commission the first few days of the drug. Then Monday, she did very well. We went to the zoo, she was up all day etc. But starting yesterday afternoon she has faultered. She is having trouble keeping things down, so I have to plan the meds at the right time. I'm going to try and take her in tommorrow to get some fluids. She is losing a lot of weight and seems dehydrated. I do believe Crizotinib is her best chance so I want to keep getting this into her.

Thanks again.

some improvement
Over the last week, my wife as made slow but steady progress. We cut back on her morphine patch last Saturday, and will likely end its uuse altogother tomorrow. She is now taking no other pain meds. She as also cut back on her nausea meds. She still has trouble eating, bt is drinking ensure and water. She is also awake about half the day. She wants to try walking again by the end of the week. I think ending the morphine will give her much more energy.

stayingcalm said:

Catcon
I haven't yet talked to my doc about trying to get on Xalkori...but I'm still hopeful!
stayingcalm

Sending Positive Vibes
Sending positive vibes your way Deb. Let us know what the doc says.

NayPaul said:

some improvement
Over the last week, my wife as made slow but steady progress. We cut back on her morphine patch last Saturday, and will likely end its uuse altogother tomorrow. She is now taking no other pain meds. She as also cut back on her nausea meds. She still has trouble eating, bt is drinking ensure and water. She is also awake about half the day. She wants to try walking again by the end of the week. I think ending the morphine will give her much more energy.

Sounds Good
That sounds more encouraging Paul. It made my heart sing just reading your last post. God bless you both and know that we all have your back!!