Taxotere and Cytoxan sde effects

laurissa said:

Hi celinelvr
I had the same for 6 rounds. Had the same effects as you. No vomiting. I didn't have the mouth sores, just the metal taste. I also had bladder infections with burning and incontinance. I went through alot of underpants. Lost taste but not appetite. It was just a strange feeling, hard to describe. Out of body is a good description. Remember-it's temporary.

Balentine said:

side effects
Dear Mary S,
To do or not to do is a decision only we can make. I am not sure what I would do if I were 67 and they told me the chemo would only give me another 9% chance that the cancer would not return. I may not decide to do it then. Most of the people on my mother's side of my family died in their 60's or 70's and I do take after that side with my high blood pressure. It is a very difficult decision because you just don't know how your body will react to the chemo. I would hate to start the chemo and then have to stop because I just could not deal with the side effects or pain but as I get closer to the start date of my first treatment which will be 3/15 all I can do is close my eyes and ask God to be with me through this as He has through my life and carry me through it....giving me His strength when mine is gone. It pretty much feels like jumping off of a dock in the dead of winter into icy waters because the dock is about to give out. You just have to pray and trust God to catch you and carry you ashore.
Lorrie

mary s said:

side effects
As I said before on this post, I had my first treatment on feb. 25th and the Neulasta shot on feb. 28th. I was fine over the weekend between these two events but then side effects galloped up on me---new ones every day! First, the nasty muscle aches and joint pains---then TIRED, then mouth sores---these all added up and I felt nasty for 4-5 days. then, all of a sudden, everything left. I still have the metal taste in my mouth but I'm going out for a walk today---used to walk 2-3 miles a day but haven't in months since tagged with this diagnosis. It's time to get out and the weather is nice here in Missouri. I don't expect to get back to the former vigor yet but I'll try for a mile today. since I know the duration of these side effects, I will be ready for them next time. Next dose is mar. 17th---celebrate St. Pat's Day in a strange fashion. I still haven't lost my hair yet but my eyelashes are thinning...ugh!

Lynda53 said:

Side affects TAC and more
I have inflammatory BC, very rare (less5%)aggressive,invasive. FTR My rt breast was minor swollen, and 10 hours later it was 2x the sieze, red , hot and hard as a rock!)
Started chemo Oct1 20009
1-I could not have adrimycin due to discovery of a-fib, HR=130.
2-No troubles w/cytoxin.
3-Taxotere./taxol a whole other story, 1st was ok, 2nd infusion I stopped breathing, readmin ok, 3rd insfusion I stopped breathing, chemo stopped mastectomy moved up.
Well found desensitzation for allergies, I had to change chemos places, but they dilluted the tax, admin slowly, 1 on 1 nurse, ICU very expensive, BUT no reactions and my last treatment was yesterday!
At every infusion: I was given iv benadryll,nausea stuff,diarrhea stuff,steroids.
At home I also took stolll softener and post chemo pills for 4 days.
My issues, mostly being tired, minor joint pain, I take a non aspirin product for it, some stomach discomfort but I have a few hiatal hernias w/patch. Vision changes but advises to wait at least 2 months after chemo to get eyes checked esp to change scripts.
I followed all onco advice, rested, and yes I did work lots of hours, hydrate,proper food intake, lots of veggies.
I did go to Look Good Feel Good from ACS a few weeks ago,I'm not a make up girl, but for those that are GO! Nice $200 bag of makeup.
I did not shave my head, although I did cut it short, I did get a wig.
I di dgo to a social worker at my cancer center for all this crap. It was ok, got some anxiety issues to deal w/and sleeplessness, and who knows! This too shall pass!
I will go on lovinox the end of the month, have the mastectomy Apr 2 (if all the Dr's say GO) and follow up rads a6 weeks and w/aromasin for 5 years.
PEACE

dawnday said:

My first time coming up
Hi. I go to the doctor Thursday to discuss the chemo. He did tell me that I would be given Taxatere and Cytoxan 4 treatments every 3 weeks. I want to be prepared and find out beforehand what to expect. All your comments have been helpful and scary. I have OCD and need to know if any of you were given the option NOT to have a port. Do they deliver the chemo IV in the vein each time?

mstrouble16 said:

taxotere and cytoxan
I started my 4 dose treatment of taxotere and cytoxan on Monday 11/7/11, during the cytoxan the nausea hit me like a brick, but came in waves, Wednesday I received my neulasta. The nausea, cramping and metal taste have been really bad so far. Oh did I mention the mood swings!!!

sweeetheart said:

Taxotere and Cytoxin with Herceptin.....SIDE EFFECTS...HELP!!!!
Hi. I am new to this website and am looking for anyone that has been experiencing long term side effects from Taxotere and Cytoxin.....I had stage 1 cancer with no node involvement...However, I have the Her 2 Neu type of breast cancer which is extremely aggressive and chemo was highly recommended...I don't want to scare anyone but my chemo has been done for a year and my radiation finished last April.....During the treatments, my scalp felt tight.....That has gone away but there have been some visual changes that have remained....such as blackness over the head and appearing in the brain....sounds strange but it is true....Everything appears darker than it used to....Artificial light is not as bright and when it is extremely bright and sunny outside, I will see it as bright but extremely....It is particularly frustrating to have this....Also my eyesight changed from 20/10 to 20/50 and for the first time in my life I will have to wear glasses to correct the eyesight and blurriness....I also see some strange things on TV...in other words, the tv does not appear as it used to....I really don't know what is going on but all of these effects were never present in m;y life before chemo.....

I also have had some concern with my short term memory.....and i also feel that certain levels of cognition are not present any longer.....Very very frustrating....

I have sunk into depression over all of this.....

I am wondering if ANYONE has had any of these side effects and if so please comment as I would really like to speak with you....

Thanks.....
Sweeetheart

witolika said:

My long term side effects from Taxotere and Cytoxan
Hello everyone. As of July 13th, 2012 I will be breast cancer free for two years. My last chemo treatment was Dec. 2nd, 2011. There were six total of which I had them every three weeks. I got both Taxotere and Cytoxan at the same time and the following day I had to have neulasta shots. I am one of the 5% that have severe side effects. I had stage three grade three aggressive infiltrating ductal carcinoma. I was lucky that it hadn't metastisized yet. I had a double mastectomy with latissimus trap reconstruction (which means they used my back instead of my stomach). After my first chemo treatment my plateletes dropped to 0.2 and they were going to hospitalize me. Instead they gave me a shot of neuprogen of which I was allergic to and it damaged my heart causing me to have two emergency stents put in my heart to keep me alive. After each treatment, even with the prescriptions they gave me for nausea, I got sick to my stomach. It would take me two weeks to be able to get out of bed with little assistance. My reconstruction healing was slowed by the chemo and I had to have one breast redone as it split open. Each chemo treatment left me completely exhausted, moderate chemo brain, difficulty sleeping due to the steroids, constant headache and ringing in my ears. A week after my first chemo I lost my hair. By the second chemo I lost all hair on my body - which kind of was a plus because I didn't have to shave and being bald helped with the really bad hot flashes! It was tough seeing myself without eyebrows and eyelashes. The fifth chemo was tough and they almost didn't give me the last one as they were afraid I was not going to make it through it. I decided to go ahead anyway as I didn't want to regret later not finishing all of the treatment. The roof of my mouth would peel after each chemo treatment. My skin on my forearms feels leathery. The neulasta shots would give me severe deep bone pain as it was forcing my bone marrow to make new blood cells. I would get these electric shocks in my spine that made me want to scream. I still get these to this day, but thankfully it is occassional and only lasts a few hours. This would last a week. Just when I was finally feeling better, almost three weeks after a treatment, I would have to go in for the next treatment. My last treatment was the worst.

So almost one and one half years after my last chemo treatment and this is what I am still going through as far as side effects. I have a constant mild headache which ramps up into a migraine three to four times a week. There are some weeks I can't get out of bed because my migraines last for days. Chronic severe fatigue causing me to have to rest, lay down, multiple times a day. I have lost more than 50% of my grip strength in my right hand and just less than that in my left with neuropathy in both. I also have a moderate tremor in both which is constant. I have transient mild amnesia which only lasts a few seconds and that happens minimum once a day. Due to the steroids and the inability to move I gained 60 pounds! I am slowly loosing it. My heart damage gives me constant chest pain and difficulty breathing. My upper body aches all the time also, that is to say the areas that I still have feeling in. I don't have feeling in the areas around my surgeries. I have constant ringing in my ears, the right much worse than the left and I am told I am slowly loosing my hearing. Short term memory, cognitive thinking and severe forgetfulness are part of my chemo brain. I went through four months of intense physical therapy which helped very little. Oh, and I was told that some time during my chemo treatments that I would lose my nails. Well it was about one and one half months after my last chemo treatment that I lost my nails and toe nails. They came back but they are thinner. My hair on my head grew back in, same color but it is curly.....yeah! My eyebrows are much thinner and so are my eyelashes but at least they came back in. The rest of the hair on my body also didn't come back in as thick. Pain, well I have constant pain in my arm pits, the right much worse than the left as that is where they took out the lymph nodes. Many times during the day the pain runs down into my hands (neuropathy). My legs, ankles and feet swell if I sit for more than half an hour. There are more minor things.

Reading this has probably scared you very much. Remember I am one of those 5% that have these severe reactions. Others that I know whom have went through chemo are doing great. Myself, I am happy to be alive and enjoy every minute that I have to live no matter what physically or mentally I have to put up with! To me it tells me I am alive! You can get through anything with a positive attitude.

A long of problems with first dose of taxotere. 2ND DOSE...ALLERGIC REACTION.A FTER 2 1/2 YEARS I STILL FEEL THE EFFECTS. UNBELIABLE FATIGUE, RUNNY NOSE AND SORE EYES. ACHE. MOOD SWINGS.NUMBNESS IN HANDS AND FEET .LEG CRAMPS. OCCASIONALLY I HAVE A GOD DAY OR TWO WHICH I TRY TO ENJOY.

JUDY