How effective have Orgavyx been for your prostate cancer after radiation treatment

Gmenbiz

Good Day Im over 60 just starting to take orgavyx for my prostate cancer. Looking at long term effects of orgavyx and how effective it has been with your final prostate care treatment. Im also getting ready for radiation treatment

Old Salt

Please provide some more info about your prostate cancer.

Very much in general, ADT is often recommended (along with radiation) when higher grade prostate has been diagnosed. The length of ADT typically varies between 6 and 24 month, depending on the Gleason score of your prostate cancer.

Many years ago I had 18 months of Lupron therapy while undergoing radiation therapy (Gleason 9). So far, so good.

swl1956

Been on Orgovyx along with Zytiga/Prednisone for about a year so far for 4+3 metastatic PCa to the pelvic lymph nodes. My Fox Chase Cancer Center oncologists recommend a total of 2 years. Like you, I started it a bit prior to IMRT. This treatment regimen has worked very well for me, now having an undetectable PSA for 9 months down from a PSA of 9 prior to treatment. This drug regimen has been tolerable but has it's challenges. I feel fairly well, but suffer a bit from fatigue, hot flashes, and not sleeping well. My oncologist has agreed I should stay on Orgovyx but to stop taking Zytiga and replace it with Nubeqa (Darolutamide) which has reportedly less side effects than Zytiga and potentially higher efficacy. Nubeqa also doesn't require Prednisone which is a big plus and I believe was keeping me from sleeping well. Anyhow, that's just my experience so far. Everyone's experience can vary. At this point in time, I believe Orgovyx to be the superior choice for ADT due to it's a daily oral medication (no shots). It can be stopped easily if needed and has a much faster testosterone recovery when compared to the injectables.