Synchronous Signet Ring Cell Carcinoma

AKRICH

Hello all, I see there doesn't appear to be any current post regarding SRCC so I thought I would start a new thread. I was diagnosed with Synchronous Signet Ring Cell Carcinoma in January '25 stage III. At that time the MDC at University of Colorado settled on chemo and radiation. FOL FOX and radiation for the rectal tumor. The thought at time was to shrink the tumors and the operate. I had a rectal tumor (Left side descending) and a cecal tumor (Right side ascending).

Well, the tumors shrugged off the Chemo as SRCC is known to do and in late September my right side cecal tumor had closed off my large intestine. The doctor went to remove the tumor and found it had spread to my abdomen. Now I have peritoneal carcinomatosis in addition.

I am no longer a candidate for surgery as the cancer has spread; and I am now considered incurable as well. I am doing palliative chemo (FOLFIRI + bevacizumab) and living my best life possible.

Current condition, 2 Nephrostomy bags (One for each kidney), 1 ileostomy bag (for colon)

My understanding is SRCC is 1% of colorectal cancers and Synchronous SRCC is 4% of the 1%.

So, the chances of having what I have is 4 out of 1000 if my math is correct.

Also, I am not a candidate for clinical trials as I am prone to kidney infections. That takes you out of the running. I am not a candidate for immunotherapy because that requires a specific genetic make up and I don't have the correct genes.

With this luck, I need to stay out of Vegas for sure :-).

The reason for this post is not to whine, as I am comfortable with my future however it plays out. I am blessed in so many was except cancer and have learned so much in the past year about people. Suddenly someone views: political, religious, social, or otherwise makes no difference. When a nurse comes to help me, I am appreciative, and when I find out someone else is fighting cancer, I am empathetic.

I would like people to know; I am here to help or listen if they need someone. I am curious if anyone else is fighting a similar diagnosis. If so, please share your experience.

Best Regards,

Rich