Massive PSA increase!

Baby_Jay

Hi guys,

I'm new to this group. I have been on TRT for the past year, my baseline PSA was .51. I just had my follow up test and today my PSA is 12.93. That is a 2,431% increase in one year. From what I'm reading, that is highly suggestive of cancer! I have seen the results through patient portal and I haven't even talked with my doctor yet. Tech suggested repeat sequential tests. My heart dropped when I saw those results. Some things I read suggested this could be a highly agressive cancer. I guess I will just take it one day at a time.

Baby_Jay

I forgot to mention I am 50 years old and my paternal grandfather had Prostate cancer, that's my only family history that I know of.

centralPA

Hey, sorry you fund yourself here.

I would definitely get another test done, just to confirm it wasn't some strange lab test error. After that, see what the doctor says. Lots of possible causes that aren't cancer, along with possibly being caused by cancer. Don't get ahead of the horse.

If cancer is truly suspected (no obvious infection causing it) then expect him to request an MRI and then perhaps a biopsy. Make sure they come in that order. The MRI steers the biopsy.

Like you said, one day at a time!

VascodaGama

I agree with above central centralPA's comments. Get another PSA in one month and check if the laboratory reports in (ng/ml) units.

Typically, aggressive prostatic cancerous cells produce low volume of PSA. Inflammation (BPH) are common in sudden increases and decreases of PSA.

Be vigilant. Get informed by professionals.

Best

VG

VascodaGama

Clevelandguy

Hi,

Why were you on TRT therapy? Is this your 1st PSA test since being on TRT? Like the other folks have suggested do more tests looking for trends up or down. Something sounds off……

Dave 3+4

Baby_Jay

https://csn.cancer.org/discussion/comment/1724281#Comment_1724281

https://csn.cancer.org/discussion/comment/1724290#Comment_1724290

Thank you, right now I'm in panic mode. That just seems like an astronomical jump in one year.

https://csn.cancer.org/discussion/comment/1724290#Comment_1724290

I'm on TRT due to severe fatigue and very low T. TRT has helped me so much to feel better. This is my second PSA test since I started.

Baby_Jay

https://csn.cancer.org/discussion/comment/1724287#Comment_1724287

Josephg

I will just re-confirm what the other folks above have stated. Panic mode is expected, and we've all been through it. It is up to you to settle and control your panic mode to the extent possible, and stay in touch with your medical professionals to get the appropriate follow-up moving forward.

Please keep us apprised with updates.

Baby_Jay

https://csn.cancer.org/discussion/comment/1724294#Comment_1724294

Thank you so much, I will.

Baby_Jay

My Doc is referring me to an oncology Urologist, so I will go from there.

Old Salt

Good advice!