Need help for my mother's Cholangiocarcinoma

ISRanderia

I am posting on behalf of my mother. She is 63 years old and was diagnosed with Cholangiocarcinoma (Bile Duct Cancer) 20 months back. When we detected it, the cancer had already spread a lot. She underwent whipples surgery, followed by 6 cycles of Gemcitabine + Capecitabine. Then another 15 rounds of radiation. We thought that would be it but the cancer spread. So we did 6 cycles of Gemcitabine + Cisplatin + Durvalumab (immunotherapy) at first the results were good but the last scan showed the cancer has spread again, affecting portal veins and more of the liver.

I am running out of options for her treatment, I am going to do the Dendritic Cell Vaccine for here, the first vial comes next week. I know it's results are mixed but at least it's some treatment with minimal side effects. Also since I live in India, we are planning to do some Tibetan herbal medicine, again not sure if it works.

I am writing this post since, I am at a dead end, is there any other for of treatment i could pursue, maybe something i missed, since it's not available in India. Read about Ivermectin and Fenbendazole but that I am unsure off, since there doesn't seem to be a proper regime for it, or at least i haven't come across any.

I am reaching out to whoever sees this or can guide me further as to what i can do in her case, though I know the possibility of her survival beyond the next 8 months is bleak, but if there is a medication or treatment I am missing I don't mind pursuing it. Thanks in advance .

P.S. there is TP53 gene mutation and HER2 negative