Bladder cancer MIBC T2, with prior diffuse large B cell lymphoma
Hello. My Dad had the above lymphoma last year went through 6 rounds of rchop and had a clear pet scan in Fall of 2024. Feb 2025 dad was diagnosed with bladder cancer, had two turbt procedures. He has elected bladder preservation treatment which means keeping his bladder and doing immmunotherapy through his existing port. He will also have ct scans and bladder scopes every 3 months. In addition, my dad has two concerning lymph nodes on the left side of his neck which are being biopsied by needle tomorrow and results will hopefully be in by the end of this week. So I am super concerned either the lymphoma has returned or the bladder cancer has spread to the lymph nodes. There was also a ct/pet scan combo done about a week ago which showed an acetabular concern with a fracture in the femur. My father has had no falls or current pain in hip/femur area, but I am also concerned of bone cancer as the above mentioned demure fracture makes no sense. Has anyone in this group had any of these things happen in a similar way?
Comments
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Sorry that he is having to deal with this. MIBC T2 bladder cancer in the past typically involved systemic neo-adjuvant chemo followed by cystectomy. New protocols have incorporated immunotherapies and other preservation techniques. The Uro folks will keep a good eye on him. In my homework, bladder cancer In the lower stages) tends to be confined to the bladder or urothelial cells from the renal pelvis all the way down through the urethra. As my onco told me when they found a progression to T2 in the biopsy of my cystectomy, Imaging technology (including PET) does not have the resolution to find very small clusters of tumor cells, so it is possible some were hiding and have made an appearance once the treatments ended.
As you may be aware, NCI hospitals are top notch places for cancer treatment, since they are on top of clinical research and state of the art treatments. You may wish to get a second opinion from one, if he is not already being seen at one. I followed up on a second opinion at an NCI hospital, and was glad that I did.
Also, bcan.org has the best curated medical info on bladder cancer out there for patients and caregivers. It also has all kinds of resources for them. If you have not visited it yet, be sure to.
Thank you for being a caregiver/concerned person, it is a critically needed role, yet one that gets little recognition. Hang in there.
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