Taking a break from Lupron

RedOrb6

just finished a 3 month Lupron shot and now PSA and testerone are virtually 0. This after prostrate removal, radiation and ADT over the past couple of years. When PSA started to rise Lupron was prescribed. It seems to have worked for now. My oncologist recommend continuing Lupron along with something additional. Is it recommendable to break for 3 months and see if PSA stays undetectable? Thx

Josephg

In my non-medical non-professional opinion, you are best to follow your Oncologist's recommendations. At this stage in your PCa journey, they are most qualified to lead the fight on your PCa journey. It seems that you are looking for layperson thoughts regarding your Oncologist's recommendations, and you now have my layperson recommendation.

Also, keep in mind that there are drugs available to minimize the adverse hot flashes effect of Lupron, and your Medical Oncologist would be the best person to discuss with and potentially prescribe to you.

RedOrb6

https://csn.cancer.org/discussion/comment/1721168#Comment_1721168

thx Joseph for your response. I consider all the chats being from laypersons so that’s true. I was hoping someone had some anecdotal advice from others experience. My oncologist laid out multiple options and lets me choose. I know what I prefer but was wondering if someone else did intermittent testosterone deprivation. Thx again

Old Salt

Yes, you should follow your medical oncologist's recommendation. How long to do ADT after 'failed surgery' and follow-up radiation is a hot topic and I certainly don't know the latest recommendations.

I do recall though that it's not uncommon to go for two years of ADT after salvage radiation.