increase in PSA post seeding

vmi59

Had seeding done 8 years ago here in Atlanta (no radiation-PSA 3.75) Cancer confirmed with biopsy. Post seeding PSA was.5. Has gradually risen until last test 3 weeks ago showed 1.47 (Oct 2024) (Mar of 2024 was 1.14). I will be 87 in Dec-should I be concerned?

Clevelandguy

Hi,

To me it sounds like your cancer has returned. If you are in good health and don’t have other severe medical problems check with your doctor team and see what they recommend. I would think a biopsy should help determine the aggressiveness of the cancer. Could be as easy as some form of radiation(Proton, Cyberknife, ect.) or you could choose to do nothing depending on the location and size of the cancer. Could take some years before the cancer grows enough to give you real quality of life issues.

Dave 3+4

Old Salt

I doubt that radiation is an option because vmi59 has undergone 'seeding' which I interpret to mean brachytherapy. More in general, a general rule' is that one waits with treatment after radiation until PSA is at least nadir (0.5 in this case) plus 2.

Perhaps a PSMA scan is warranted, but at age 87? Good to discuss this with a radiation oncologist.

Clevelandguy

https://csn.cancer.org/discussion/comment/1718569#Comment_1718569

Hi,

Proton radiation can be used if other forms of radiation have failed.

Dave 3+4