Stage 3 Rectal cancer Recurrence

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hasanghp
hasanghp Member Posts: 4
edited October 2024 in Colorectal Cancer #1

Hi

I am male with 37 years old

I was diagnosed with stage 3 rectum cancer Aug 2023 about 6 cm tumor in my rectum and 8 cm distance to anal verge .I did first CT for checking metastas and it was clear.

My oncologist decided 6 rounds of chemotherapy with folfox. After it was ended, I did my second CT and shows that tumor size has been reduced about 50%, at least 4 lymph are in abnormal size, also a sub centimeter lesion in Lt. lobe 4 of my liver that should be follow up.

after that I started 28 radiotherapy plus oral xeloda. At Feb 2024 I did LAR surgery. Pathology answer shows 4/5 lymph invasions and margins are free and IHC results showed wild kras and no mutation . Apr 2024 reversed colestomy. After that I did 6 Adjuvant chemo with Folfox + Cetuximab+Bevacizumab. All process was completed at Jun 2024.
1 week ago I did first follow up PET/CT after 3 months from last chemo ending and unfortunately it shows 1 tumor in lobe 6 of my liver about 1cm dimension. after I have seen this result I’m so feared and scared. My oncologist suggested interventional radiology to destroy tumor. I didn’t expect recurrence to occur in this short time

Comments

  • SnapDragon2
    SnapDragon2 CSN Member Posts: 721 Member
    #2

    Research Histotripsy for liver mets.

  • Trubrit
    Trubrit CSN Member Posts: 5,805 Member
    #3

    Hello, and welcome to the forum.

    I was diagnosed 12 years ago, had surgery, then chemo and radiation. My first scan post treatment showed a lesion in the liver. Like you, I was devastated and shocked. I was only 3 months out from treatment. I had that lesion ablated, and that was 10 years ago. I have had no other problems since then. Ablation isn't for everyone, there are restrictions, but it is worth talking to your Oncologist and Surgeon.

    I wish you the best. TRU

  • hasanghp
    hasanghp Member Posts: 4
    #4

    my liver ablation was postponed due to some nodule in my lungs, 4 nodules, bigger one is 8mm with 1.25 SUV max. some of nodules are inactive. I hadn’t nodule in CT at first 6 round of chemo. Is it possible that nodules has been inactive because of second round of chemo that I did after surgery?

    my first oncologist ignored nodules and refer me for liver ablation with RF. But another oncologist suggested chemo before surgery.

    So I decided to do chemo Irrinotecan+xeloda+avastin every 3week

    Now I’m in 4th round and I will check in coming days

  • hasanghp
    hasanghp Member Posts: 4
    #5

    Hi everyone

    After above regimen, CT shows more lung nodule’s and sizes got biger. Also liver lesion got bigger, so my oncologist decided to change regimen and chooses

    +cetuximab

    After 8 sessions of Folfirinox+cetuximab, almost 90% of Lung nudule have gone and just 2 of 2mm and 1 of 3mm has remain. Liver lesion has decreased from 25x22mm to 10x6mm. My oncologist decided to continue this regimen for 4 more sessions and then decide to surgery remaining lesions

    One question:

    Is anyway to surgery under 5mm nodule in lung? My lung nodule’s are very small and base of my research there is no approved surgical operation to remove these so little tumors, am I right?

  • hasanghp
    hasanghp Member Posts: 4
    #6
  • bibliophile
    bibliophile CSN Member Posts: 39 Member
    #7
    https://csn.cancer.org/discussion/comment/1723433#Comment_1723433

    How well are you tolerating the FOLFIRINOX? I just started yesterday and it was brutal! Way worse than the CAPEOX I did the first time around. I had a really bad reaction to the Irinotecan. Starting to feel a little better today. As to the lung nodules, I had one removed in March at 7mm and my surgeon said that was the very low end of size that he felt he could even find to remove. It is great that your nodules have shrunk so much! Maybe now they can just concentrate on the liver lesions. Wishing you the best!

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