Reduced chemo radiation clinical trial for early detected anal cancer

Maulie

I am wondering if anyone has been offered this option for treatment. This is a 2 arm study, randomized selection of standard treatment or trial group. Qualifications; T1 or T2, no lymph node or Mets detected.

The purpose of this study is to determine if reduction of treatment in early stage anal cancer provides similar efficacy as standard treatment with reduction of short and long term side effects. If selected for the trial, chemo and radiation is reduced to 20-23 days, with gy radiation reduction too.

Limited results with data right now. Early data is showing 90% clear after 6 mos. Would you go for it or is the risk too great?

Maulie

dssdesi

Possibly , I took the pills instead of the pump for Fu and skipped my last metomycin dose. All clear so far. I was T1 no mo and most of tumor was removed (2cm) only dysplasia left when started Chemo/rt

Jet1204

I had stage 1 and it did not go to lymph nodes. I did chemo/raidiation. I think it was 24 days radiation. I was diagnosed Jan 2024 and supposedly cancer free in June 2024. I have a pelvic ultrasound next week to make sure lymph nodes are still okay and a possible pet scan soon to double check everything. It was the only option I was given.